FGF21 induces autophagy‐mediated cholesterol efflux to inhibit atherogenesis via RACK1 up‐regulation

The roles of FGF21 in atherosclerosis pathogenesis

(2019) Farzane Shanebandpour Tabari et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Fibroblast growth factor 21 in lipid metabolism and non-alcoholic fatty liver disease

(2019) Xin Su et al.   CLINICA CHIMICA ACTA

Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis

(2018) Xinxin Yan et al.   Lipids in Health and Disease

Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease

(2018) Eithne M. Maguire et al.   VASCULAR PHARMACOLOGY

Fibroblast growth factor 21 regulates foam cells formation and inflammatory response in Ox-LDL-induced THP-1 macrophages

(2018) Nan Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

AMPK: Regulation of Metabolic Dynamics in the Context of Autophagy

(2018) Isaac Tamargo-Gómez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fibroblast growth factor 21 for non-alcoholic steatohepatitis

(2018) Vincent W S Wong et al.   LANCET

Allicin induces the upregulation of ABCA1 expression via PPARγ/LXRα signaling in THP-1 macrophage-derived foam cells

(2017) Xiao-Long Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The roles of macrophage autophagy in atherosclerosis

(2016) Bo-zong Shao et al.   ACTA PHARMACOLOGICA SINICA

Macrophage Phenotype and Function in Different Stages of Atherosclerosis

(2016) Ira Tabas et al.   CIRCULATION RESEARCH

Fibroblast growth factor 21 (FGF21) inhibits macrophage-mediated inflammation by activating Nrf2 and suppressing the NF-κB signaling pathway

(2016) Yinhang Yu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

AMPK activates LXRα and ABCA1 expression in human macrophages

(2016) Marina Kemmerer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy

(2016) Secil Erbil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficit of RACK1 contributes to the spatial memory impairment via upregulating BECLIN1 to induce autophagy

(2016) Jiejun Zhu et al.   LIFE SCIENCES

Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas

(2016) Garima Singhal et al.   PLoS One

Apelin-13 impedes foam cell formation by activating Class III PI3K/Beclin-1-mediated autophagic pathway

(2015) Feng Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Mechanisms of Autophagy in the Cardiovascular System

(2015) D. Gatica et al.   CIRCULATION RESEARCH

Curcumin Enhanced Cholesterol Efflux by Upregulating ABCA1 Expression Through AMPK-SIRT1-LXRα Signaling in THP-1 Macrophage-Derived Foam Cells

(2015) Xiao-long Lin et al.   DNA AND CELL BIOLOGY

PKCs in thrombus formation

(2015) Y. Zaid et al.   PATHOLOGIE BIOLOGIE

IRE1–RACK1 axis orchestrates ER stress preconditioning-elicited cytoprotection from ischemia/reperfusion injury in liver

(2015) Dong Liu et al.   Journal of Molecular Cell Biology

RACK1 Promotes Autophagy by Enhancing the Atg14L-Beclin 1-Vps34-Vps15 Complex Formation upon Phosphorylation by AMPK

(2015) Yawei Zhao et al.   Cell Reports

FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway

(2014) S. Zhu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Effects of fibroblast growth factor 21 on cell damage in vitro and atherosclerosis in vivo

(2014) Wenhe Zhu et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

mTOR Enhances Foam Cell Formation by Suppressing the Autophagy Pathway

(2014) Xiaochuang Wang et al.   DNA AND CELL BIOLOGY

FGF21 Increases Cholesterol Efflux by Upregulating ABCA1 Through the ERK1/2–PPARγ–LXRα Pathway in THP1 Macrophage-Derived Foam Cells

(2014) Xiao-Long Lin et al.   DNA AND CELL BIOLOGY

Possible role of fibroblast growth factor 21 on atherosclerosis via amelioration of endoplasmic reticulum stress-mediated apoptosis in apoE−/− mice

(2014) Xi Wu et al.   HEART AND VESSELS

Foam cells in atherosclerosis

(2013) Xiao-Hua Yu et al.   CLINICA CHIMICA ACTA

Cholesterol Efflux and Atheroprotection

(2012) Robert S. Rosenson et al.   CIRCULATION

Regulation of Lipid Droplet Cholesterol Efflux From Macrophage Foam Cells

(2011) Mireille Ouimet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE