Gene Ontology Curation of Neuroinflammation Biology Improves the Interpretation of Alzheimer’s Disease Gene Expression Data

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0)

(2019) Huaiyu Mi et al.   Nature Protocols

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Systematic Review of miRNA as Biomarkers in Alzheimer’s Disease

(2019) S. Swarbrick et al.   MOLECULAR NEUROBIOLOGY

Emerging Role of microRNAs in Dementia

(2019) Sarayu Ramakrishna et al.   JOURNAL OF MOLECULAR BIOLOGY

The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques

(2019) Carlo Sala Frigerio et al.   Cell Reports

Current and emerging avenues for Alzheimer's disease drug targets

(2019) R. Loera‐Valencia et al.   JOURNAL OF INTERNAL MEDICINE

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

(2019) Frank Koopmans et al.   NEURON

Informing disease modelling with brain-relevant functional genomic annotations

(2019) Regina H Reynolds et al.   BRAIN

Exploring autophagy with Gene Ontology

(2018) Paul Denny et al.   Autophagy

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

The Evolving Dialogue of Microglia and Neurons in Alzheimer’s Disease: Microglia as Necessary Transducers of Pathology

(2018) E. Simon et al.   NEUROSCIENCE

Expanding the horizons of microRNA bioinformatics

(2018) Rachael P. Huntley et al.   RNA

Early Life Stress and Epigenetics in Late-onset Alzheimer’s Dementia: A Systematic Review

(2018) Erwin Lemche   CURRENT GENOMICS

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

(2018) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

RNAcentral: a hub of information for non-coding RNA sequences

(2018) et al.   NUCLEIC ACIDS RESEARCH

ECO, the Evidence & Conclusion Ontology: community standard for evidence information

(2018) Michelle Giglio et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Improving the Gene Ontology Resource to Facilitate More Informative Analysis and Interpretation of Alzheimer’s Disease Data

(2018) Barbara Kramarz et al.   Genes

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Regeneration of the entire human epidermis using transgenic stem cells

(2017) Tobias Hirsch et al.   NATURE

Ensembl 2018

(2017) Daniel R Zerbino et al.   NUCLEIC ACIDS RESEARCH

miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions

(2017) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

WebGestalt 2017: a more comprehensive, powerful, flexible and interactive gene set enrichment analysis toolkit

(2017) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease

(2016) Claudio Villegas-Llerena et al.   CURRENT OPINION IN NEUROBIOLOGY

Inflammasomes link vascular disease with neuroinflammation and brain disorders

(2016) Nikolett Lénárt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

(2016) Celeste Sassi et al.   NEUROBIOLOGY OF AGING

Using the Gene Ontology to Annotate Key Players in Parkinson’s Disease

(2016) R. E. Foulger et al.   NEUROINFORMATICS

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

(2016) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

Guidelines for the functional annotation of microRNAs using the Gene Ontology

(2016) Rachael P. Huntley et al.   RNA

The Protective Role of microRNA-200c in Alzheimer's Disease Pathologies Is Induced by Beta Amyloid-Triggered Endoplasmic Reticulum Stress

(2016) Qi Wu et al.   Frontiers in Molecular Neuroscience

Gene Prioritization for Imaging Genetics Studies Using Gene Ontology and a Stratified False Discovery Rate Approach

(2016) Sejal Patel et al.   Frontiers in Neuroinformatics

Proteogenomics of the human hippocampus: The road ahead

(2015) Myoung-Goo Kang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Using Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autism

(2015) Sejal Patel et al.   BMC BIOINFORMATICS

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Visual annotation display (VLAD): a tool for finding functional themes in lists of genes

(2015) Joel E. Richardson et al.   MAMMALIAN GENOME

A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia

(2015) Raffaele Ferrari et al.   NEUROBIOLOGY OF AGING

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The Reactome pathway Knowledgebase

(2015) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

A method for increasing expressivity of Gene Ontology annotations using a compositional approach

(2014) Rachael P Huntley et al.   BMC BIOINFORMATICS

Reuse of termino-ontological resources and text corpora for building a multilingual domain ontology: An application to Alzheimer’s disease

(2014) Khadim Dramé et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128

(2014) Yogita K Adlakha et al.   Molecular Cancer

Tracking the earliest pathologic changes in Alzheimer disease

(2014) S. M. Landau et al.   NEUROLOGY

miR26a Modulates Th17/Treg Balance in the EAE Model of Multiple Sclerosis by Targeting IL6

(2014) Rongwei Zhang et al.   NEUROMOLECULAR MEDICINE

Genenames.org: the HGNC resources in 2015

(2014) Kristian A. Gray et al.   NUCLEIC ACIDS RESEARCH

The complex portal - an encyclopaedia of macromolecular complexes

(2014) Birgit H.M. Meldal et al.   NUCLEIC ACIDS RESEARCH

Gene: a gene-centered information resource at NCBI

(2014) Garth R. Brown et al.   NUCLEIC ACIDS RESEARCH

miR-29b suppresses tumor growth and metastasis in colorectal cancer via downregulating Tiam1 expression and inhibiting epithelial–mesenchymal transition

(2014) B Wang et al.   Cell Death & Disease

ADO: A disease ontology representing the domain knowledge specific to Alzheimer's disease

(2013) Ashutosh Malhotra et al.   Alzheimers & Dementia

A new reference implementation of the PSICQUIC web service

(2013) Noemi del-Toro et al.   NUCLEIC ACIDS RESEARCH

The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

(2013) Sandra Orchard et al.   NUCLEIC ACIDS RESEARCH

A guide to best practices for Gene Ontology (GO) manual annotation

(2013) R. Balakrishnan et al.   Database-The Journal of Biological Databases and Curation

Common Alzheimer’s Disease Research Ontology: National Institute on Aging and Alzheimer’s Association Collaborative Project

(2012) Lorenzo M. Refolo et al.   Alzheimers & Dementia

The MicroRNA-17-92 Family of MicroRNA Clusters in Development and Disease

(2012) Carla P. Concepcion et al.   CANCER JOURNAL

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

(2012) Peter Holmans et al.   HUMAN MOLECULAR GENETICS

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium

(2012) Sandra Orchard et al.   NATURE METHODS

Gene expression profiling in human neurodegenerative disease

(2012) Johnathan Cooper-Knock et al.   Nature Reviews Neurology

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detection of MicroRNAs in Microglia by Real-time PCR in Normal CNS and During Neuroinflammation

(2012) Tatiana Veremeyko et al.   Jove-Journal of Visualized Experiments

miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened

(2011) Xiao-Hui Huang et al.   JOURNAL OF PATHOLOGY

The projected effect of risk factor reduction on Alzheimer's disease prevalence

(2011) Deborah E Barnes et al.   LANCET NEUROLOGY

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Gene expression reveals overlap between normal aging and Alzheimer's disease genes

(2010) Dimitrios Avramopoulos et al.   NEUROBIOLOGY OF AGING

Network-Like Impact of MicroRNAs on Neuronal Lineage Differentiation of Unrestricted Somatic Stem Cells from Human Cord Blood

(2010) Katharina M. Iwaniuk et al.   STEM CELLS AND DEVELOPMENT

Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder

(2009) Peter Holmans et al.   AMERICAN JOURNAL OF HUMAN GENETICS

QuickGO: a web-based tool for Gene Ontology searching

(2009) D. Binns et al.   BIOINFORMATICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

QuickGO: a user tutorial for the web-based Gene Ontology browser

(2009) Rachael P. Huntley et al.   Database-The Journal of Biological Databases and Curation

Improvements to cardiovascular Gene Ontology

(2008) Ruth C. Lovering et al.   ATHEROSCLEROSIS

AmiGO: online access to ontology and annotation data

(2008) Seth Carbon et al.   BIOINFORMATICS

Emerging and potential therapies for Alzheimer's disease

(2008) Heledd H Griffiths et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY