Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice

Title
Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice
Authors
Keywords
Tivozanib, ABCB1, ABCG2, Oatp1a/1b, CYP3A enzymes, Brain penetration
Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 581, Issue -, Pages 119277
Publisher
Elsevier BV
Online
2020-03-28
DOI
10.1016/j.ijpharm.2020.119277

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