Recombinase-mediated cassette exchange (RMCE) for monoclonal antibody expression in the commercially relevant CHOK1SV cell line

Fast identification of reliable hosts for targeted cell line development from a limited-genome screening using combined φC31 integrase and CRE-Lox technologies

(2013) Yongping Crawford et al.   BIOTECHNOLOGY PROGRESS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Repeated integration of antibody genes into a pre-selected chromosomal locus of CHO cells using an accumulative site-specific gene integration system

(2011) Yoshinori Kawabe et al.   CYTOTECHNOLOGY

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

(2011) Xun Xu et al.   NATURE BIOTECHNOLOGY

High-level transgene expression by homologous recombination-mediated gene transfer

(2011) Mélanie Grandjean et al.   NUCLEIC ACIDS RESEARCH

Strategies for selecting Recombinant CHO cell lines for cGMP manufacturing: Realizing the potential in bioreactors

(2010) Alison J. Porter et al.   BIOTECHNOLOGY PROGRESS

Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system

(2010) Hong Zhou et al.   JOURNAL OF BIOTECHNOLOGY

Multiplexing RMCE: Versatile Extensions of the Flp-Recombinase-Mediated Cassette-Exchange Technology

(2010) Soeren Turan et al.   JOURNAL OF MOLECULAR BIOLOGY

Utilization of Site-Specific Recombination for Generating Therapeutic Protein Producing Cell Lines

(2010) Margie Campbell et al.   MOLECULAR BIOTECHNOLOGY

Using microarray technology to select housekeeping genes in Chinese hamster ovary cells

(2009) Scott M. Bahr et al.   BIOTECHNOLOGY AND BIOENGINEERING

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

Intraclonal Protein Expression Heterogeneity in Recombinant CHO Cells

(2009) Warren Pilbrough et al.   PLoS One

The molecular basis for stability of heterochromatin-mediated silencing in mammals

(2009) Kyoko Hiragami-Hamada et al.   Epigenetics & Chromatin