Hematological Diseases and Osteoporosis

Pathogenesis of Thalassemia Major-associated Osteoporosis: A Review with Insights from Clinical Experience

(2019) Agostino Gaudio et al.   Journal of Clinical Research in Pediatric Endocrinology

Sickle cell disease: a review for the internist

(2019) Valeria Maria Pinto et al.   Internal and Emergency Medicine

Bone health in symptomatic carriers of haemophilia A: a protocol for a multicentre prospective matched-cohort study

(2019) Grace H Tang et al.   BMJ Open

Increased bone resorption in hemophilia

(2018) E. Carlos Rodriguez-Merchan et al.   BLOOD REVIEWS

High bone mineral density in sickle cell disease: Prevalence and characteristics

(2018) Gonzalo De Luna et al.   BONE

Bone and blood interactions in human health and disease

(2018) Rodrigo J. Valderrábano et al.   BONE

The role of biphosphonates in the management of thalassemia-induced osteoporosis: a systematic review and meta-analysis

(2018) Athanasios N. Tsartsalis et al.   Hormones-International Journal of Endocrinology and Metabolism

Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential

(2018) Ingrid Spaan et al.   Journal of Hematology & Oncology

Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: an international, double-blind, double-dummy, randomised, controlled, phase 3 study

(2018) Noopur Raje et al.   LANCET ONCOLOGY

Myeloma Bone Disease: Update on Pathogenesis and Novel Treatment Strategies

(2018) Sonia Vallet et al.   Pharmaceutics

Hypercalcemia remains an adverse prognostic factor for newly diagnosed multiple myeloma patients in the era of novel antimyeloma therapies

(2017) Flora Zagouri et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Monoclonal gammopathy of undetermined significance and bone health outcomes: a systematic review and exploratory meta-analysis

(2017) Nicola Veronese et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Vitamin D Deficiency in Adult Sickle Cell Patients

(2017) Peter C. Boettger et al.   JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION

Genetic deletion of Sost or pharmacological inhibition of sclerostin prevent multiple myeloma-induced bone disease without affecting tumor growth

(2017) J Delgado-Calle et al.   LEUKEMIA

Sclerostin is a possible candidate marker of arterial stiffness: Results from a cohort study in Catania

(2017) Agostino Gaudio et al.   Molecular Medicine Reports

Evaluation of bone mineral density in children with sickle-cell anemia and its associated factors in the south of Iran: a case-control study

(2017) Mohammad Reza Bordbar et al.   Archives of Osteoporosis

Longitudinal changes of endocrine and bone disease in adults with β-thalassemia major receiving different iron chelators over 5 years

(2016) Maurizio Poggi et al.   ANNALS OF HEMATOLOGY

Management of beta-thalassemia-associated osteoporosis

(2016) Andrea Giusti et al.   Annals of the New York Academy of Sciences

Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts

(2016) Peter Valent et al.   BLOOD

β-Thalassemia

(2016) Raffaella Origa   GENETICS IN MEDICINE

Multiple Myeloma: Diagnosis and Treatment

(2016) S. Vincent Rajkumar et al.   MAYO CLINIC PROCEEDINGS

Thalassemia-associated osteoporosis: a systematic review on treatment and brief overview of the disease

(2016) A. D. Dede et al.   OSTEOPOROSIS INTERNATIONAL

Endocrine manifestations of systemic mastocytosis in bone

(2016) Loren Wissner Greene et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Dickkopf-1 and Sclerostin Serum Levels in Patients with Systemic Mastocytosis

(2015) Maurizio Rossini et al.   CALCIFIED TISSUE INTERNATIONAL

Iron Chelation in Thalassemia Major

(2015) Caterina Borgna-Pignatti et al.   CLINICAL THERAPEUTICS

MANAGEMENT OF ENDOCRINE DISEASE: Secondary osteoporosis: pathophysiology and management

(2015) Faryal Mirza et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Erythropoietin directly stimulates osteoclast precursors and induces bone loss

(2015) Sahar Hiram-Bab et al.   FASEB JOURNAL

Bone health in persons with haemophilia

(2015) C. L. Kempton et al.   HAEMOPHILIA

Effects of strontium ranelate on bone mass and bone turnover in women with thalassemia major-related osteoporosis

(2015) Nunziata Morabito et al.   JOURNAL OF BONE AND MINERAL METABOLISM

The Proteasome Inhibitor Bortezomib Maintains Osteocyte Viability in Multiple Myeloma Patients by Reducing Both Apoptosis and Autophagy: A New Function for Proteasome Inhibitors

(2015) Denise Toscani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A Rapid Skeletal Turnover in Radiographic Mimic of Osteopetrosis Might Be Secondary to Systemic Mastocytosis

(2015) Maurizio Rossini et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoporosis: the evolution of a diagnosis

(2015) M. Lorentzon et al.   JOURNAL OF INTERNAL MEDICINE

Effects of teriparatide retreatment in a patient with β-thalassemia major

(2015) Symeon Tournis et al.   TRANSFUSION

Factors associated with an increased risk of vertebral fracture in monoclonal gammopathies of undetermined significance

(2015) J M Piot et al.   Blood Cancer Journal

Chronic Iron Deficiency as an Emerging Risk Factor for Osteoporosis: A Hypothesis

(2015) Laura Toxqui et al.   Nutrients

Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells

(2015) Rinaldo Florencio-Silva et al.   Biomed Research International

Zoledronic Acid in Osteoporosis Secondary to Mastocytosis

(2014) Maurizio Rossini et al.   AMERICAN JOURNAL OF MEDICINE

A Phase IB multicentre dose-determination study of BHQ880 in combination with anti-myeloma therapy and zoledronic acid in patients with relapsed or refractory multiple myeloma and prior skeletal-related events

(2014) Swaminathan P. Iyer et al.   BRITISH JOURNAL OF HAEMATOLOGY

The clinical relevance and management of monoclonal gammopathy of undetermined significance and related disorders: recommendations from the European Myeloma Network

(2014) N. W. C. J. van de Donk et al.   HAEMATOLOGICA

Bone Involvement and Osteoporosis in Mastocytosis

(2014) Maurizio Rossini et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Bisphosphonates in the treatment of thalassemia-associated osteoporosis

(2014) A. Gaudio et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Bone mineral density in men and children with haemophilia A and B: a systematic review and meta-analysis

(2014) S. A. Paschou et al.   OSTEOPOROSIS INTERNATIONAL

Altered cortical microarchitecture in patients with monoclonal gammopathy of undetermined significance

(2013) J. N. Farr et al.   BLOOD

Serum levels of bone cytokines are increased in indolent systemic mastocytosis associated with osteopenia or osteoporosis

(2013) Anja Rabenhorst et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Unrecognized Vertebral Fractures in Adolescents and Young Adults With Thalassemia Syndromes

(2013) Pontipa Engkakul et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Increased osteoblast and osteoclast indices in individuals with systemic mastocytosis

(2013) S. Seitz et al.   OSTEOPOROSIS INTERNATIONAL

The effect of monthly ibandronate on bone mineral density and bone turnover markers in patients with haemophilia A and B and increased risk for fracture

(2013) Timoleon-Achilleas Vyzantiadis et al.   THROMBOSIS AND HAEMOSTASIS

High prevalence of fractures and osteoporosis in patients with indolent systemic mastocytosis

(2012) E. Veer et al.   ALLERGY

Bone Complications of Mastocytosis: A Link between Clinical and Biological Characteristics

(2012) Nicolas Guillaume et al.   AMERICAN JOURNAL OF MEDICINE

Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy

(2012) E. Terpos et al.   ANNALS OF ONCOLOGY

Bone health in persons with haemophilia: a review

(2012) Kanjaksha Ghosh et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

High Circulating Sclerostin is Present in Patients with Thalassemia-associated Osteoporosis and Correlates with Bone Mineral Density

(2012) E. Voskaridou et al.   HORMONE AND METABOLIC RESEARCH

Reduced bone mineral density in patients with haemophilia A and B in Northern Greece

(2012) Sofia Vakalopoulou et al.   THROMBOSIS AND HAEMOSTASIS

Osteocytes: central conductors of bone biology in normal and pathological conditions

(2011) A. Neve et al.   Acta Physiologica

Interferon Alpha and Pamidronate in Osteoporosis with Fracture Secondary to Mastocytosis

(2011) Michel Laroche et al.   AMERICAN JOURNAL OF MEDICINE

Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1  levels in patients with MGUS

(2011) A. C. Ng et al.   BLOOD

Bone mineral density, bone turnover markers and fractures in patients with indolent systemic mastocytosis

(2011) Maurizio Rossini et al.   BONE

Role of exercise and physical activity on haemophilic arthropathy, fall prevention and osteoporosis

(2011) A. L. FORSYTH et al.   HAEMOPHILIA

Systemic mastocytosis and bone involvement in a cohort of 75 patients

(2010) S. Barete et al.   ANNALS OF THE RHEUMATIC DISEASES

Monoclonal gammopathy of undetermined significance and risk of skeletal fractures: a population-based study

(2010) S. Y. Kristinsson et al.   BLOOD

Role of genetic pattern on bone mineral density in thalassemic patients

(2010) Agostino Gaudio et al.   CLINICAL BIOCHEMISTRY

Increased Sclerostin Serum Levels Associated with Bone Formation and Resorption Markers in Patients with Immobilization-Induced Bone Loss

(2010) Agostino Gaudio et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management

(2010) R A Kyle et al.   LEUKEMIA

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

(2010) S. Vallet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bone mineral density in haemophilia patients

(2010) Gianluigi Fabbriciani et al.   THROMBOSIS AND HAEMOSTASIS

Histamine Promotes Osteoclastogenesis through the Differential Expression of Histamine Receptors on Osteoclasts and Osteoblasts

(2009) Martin Biosse-Duplan et al.   AMERICAN JOURNAL OF PATHOLOGY

The use of bisphosphonates in multiple myeloma: recommendations of an expert panel on behalf of the European Myeloma Network

(2009) E. Terpos et al.   ANNALS OF ONCOLOGY

Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors

(2009) K.-H. Lim et al.   BLOOD

Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

(2009) M. Fulciniti et al.   BLOOD

Prevalence and risk factors associated with decreased bone mineral density in patients with haemophilia

(2009) G. GERSTNER et al.   HAEMOPHILIA

Disease Associations With Monoclonal Gammopathy of Undetermined Significance: A Population-Based Study of 17,398 Patients

(2009) John P. Bida et al.   MAYO CLINIC PROCEEDINGS

Pediatric-onset mastocytosis: A long term clinical follow-up and correlation with bone marrow histopathology

(2009) Ashraf Uzzaman et al.   PEDIATRIC BLOOD & CANCER

Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia

(2008) Ellen B. Fung et al.   BONE

The Effects of Alendronate Treatment in Osteoporotic Patients Affected by Monoclonal Gammopathy of Undetermined Significance

(2008) Jessica Pepe et al.   CALCIFIED TISSUE INTERNATIONAL

CC-Chemokine Ligand 20/Macrophage Inflammatory Protein-3  and CC-Chemokine Receptor 6 Are Overexpressed in Myeloma Microenvironment Related to Osteolytic Bone Lesions

(2008) N. Giuliani et al.   CANCER RESEARCH

Zoledronic Acid Markedly Improves Bone Mineral Density for Patients with Monoclonal Gammopathy of Undetermined Significance and Bone Loss

(2008) J. R. Berenson et al.   CLINICAL CANCER RESEARCH

Bone demineralization in adult thalassaemic patients: contribution of GH and IGF-I at different skeletal sites

(2008) Massimo Scacchi et al.   CLINICAL ENDOCRINOLOGY

Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma

(2008) Deborah J Heath et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone Disease in Thalassemia: A Frequent and Still Unresolved Problem

(2008) Maria G Vogiatzi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Denosumab, a Fully Human Monoclonal Antibody to RANKL, Inhibits Bone Resorption and Increases BMD in Knock-In Mice That Express Chimeric (Murine/Human) RANKL*

(2008) Paul J Kostenuik et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone marrow microenvironment and the identification of new targets for myeloma therapy

(2008) K Podar et al.   LEUKEMIA