Intratumoral heterogeneity and genetic characteristics of prostate cancer

Comprehensive Characterization of Cancer Driver Genes and Mutations

(2018) Matthew H. Bailey et al.   CELL

Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer

(2018) Yi-Mi Wu et al.   CELL

Targeting DNA Repair in Prostate Cancer

(2018) Wassim Abida et al.   JOURNAL OF CLINICAL ONCOLOGY

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

(2018) David C. Wedge et al.   NATURE GENETICS

Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity

(2018) Emelie Berglund et al.   Nature Communications

Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity

(2018) Marthe Løvf et al.   EUROPEAN UROLOGY

Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

(2018) Haley Hieronymus et al.   eLife

Intratumoral and Intertumoral Genomic Heterogeneity of Multifocal Localized Prostate Cancer Impacts Molecular Classifications and Genomic Prognosticators

(2017) Lei Wei et al.   EUROPEAN UROLOGY

Frequency of DNA repair gene mutations in localized and metastatic prostate cancer.

(2017) Marc Dall'Era et al.   JOURNAL OF CLINICAL ONCOLOGY

EPG5-related Vici syndrome: a paradigm of neurodevelopmental disorders with defective autophagy

(2016) Susan Byrne et al.   BRAIN

The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis

(2016) Megan L. Goodall et al.   DEVELOPMENTAL CELL

Atg7cooperates withPtenloss to drive prostate cancer tumor growth

(2016) Urmila Santanam et al.   GENES & DEVELOPMENT

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

(2016) Colin C. Pritchard et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer

(2015) P. M. Scarbrough et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Integrative Clinical Genomics of Advanced Prostate Cancer

(2015) Dan Robinson et al.   CELL

The Molecular Taxonomy of Primary Prostate Cancer

(2015) Adam Abeshouse et al.   CELL

Spatial genomic heterogeneity within localized, multifocal prostate cancer

(2015) Paul C Boutros et al.   NATURE GENETICS

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

(2015) Colin S Cooper et al.   NATURE GENETICS

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

(2015) Joaquin Mateo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+Breast Cancer

(2014) David Endesfelder et al.   CANCER RESEARCH

Copy number alteration burden predicts prostate cancer relapse

(2014) H. Hieronymus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intratumor DNA Methylation Heterogeneity Reflects Clonal Evolution in Aggressive Prostate Cancer

(2014) David Brocks et al.   Cell Reports

Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins

(2012) Johan Lindberg et al.   EUROPEAN UROLOGY

Validating the Interval to Biochemical Failure for the Identification of Potentially Lethal Prostate Cancer

(2012) Mark K. Buyyounouski et al.   JOURNAL OF CLINICAL ONCOLOGY

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

(2011) Fernando Calvo et al.   NATURE CELL BIOLOGY

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms

(2010) Ye Tian et al.   CELL