Article
Surgery
Amisha N. Parikh, Taylor C. Merritt, Horacio G. Carvajal, Mark S. Shepard, Matthew W. Canter, Aaron M. Abarbanell, Pirooz Eghtesady, Dilip S. Nath
Summary: Objective data on adult lung transplantation suggest perioperative benefits of intraoperative ECMO compared to CPB. This study compares outcomes of intraoperative ECMO versus CPB in pediatric lung transplantation, showing that ECMO support may decrease intraoperative transfusion requirements compared to CPB. Additional data from other institutions may strengthen these observations.
CLINICAL TRANSPLANTATION
(2021)
Article
Cardiac & Cardiovascular Systems
Jawad Salman, Beeke-Alina Bernhard, Fabio Ius, Reza Poyanmehr, Wiebke Sommer, Khalil Aburahma, Hani Alhadidi, Thierry Siemeni, Christian Kuehn, Murat Avsar, Axel Haverich, Gregor Warnecke, Igor Tudorache
Summary: This study aimed to identify risk factors for the need of intra-operative ECMO use in lung transplant patients with pulmonary fibrosis. Factors such as preoperative proof of pulmonary hypertension, mean pulmonary arterial pressure, and pulmonary vascular resistance were identified as risk factors, while increased recipient body surface area and higher cardiac output were protective factors. The post-operative course was found to be more complicated in the ECMO+ group, although long-term survival did not differ significantly among groups.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Yan Zhang, Bo Wang, Xiu-Juan Zhou, Li-Juan Guo, Rong-Hua Zhou
Summary: The study found that the lowest suitable DO(2)i threshold during pediatric CPB in infants undergoing cardiac surgery was 353 mL/min/m², below which there was a high probability of inducing CS-AKI and increasing postoperative morbidity.
ANNALS OF THORACIC SURGERY
(2022)
Article
Pediatrics
Alejandro Garcia, Eric W. Etchill, Melania M. Bembea, Brian W. Gray, Daniel S. Rhee
Summary: Retrospective review of the ELSO database showed that larger arterial cannulas are not necessary to achieve similar pump flows for hemodynamic support compared to 15-16Fr cannulas, but larger cannula sizes may increase the risk of ischemic complications.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Review
Cardiac & Cardiovascular Systems
Akihiro Ohsumi, Hiroshi Date
Summary: ECMO has shown benefits in reducing postoperative complications and improving short-term outcomes in lung transplantation. Both intraoperative and preoperative use of ECMO have demonstrated favorable results, but further data from large multicenter randomized controlled trials are needed.
GENERAL THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Review
Critical Care Medicine
Ricardo Teijeiro-Paradis, Tsega Cherkos Dawit, Laveena Munshi, Niall D. Ferguson, Eddy Fan
Summary: The methods and criteria for liberating patients from ECMO vary and are influenced by individual clinician preferences. Further research on liberation thresholds is needed to define optimal liberation strategies and address knowledge gaps in essential topics related to liberation from venovenous ECMO.
Article
Pediatrics
Ze-Wei Lin, Ying-Ying Liu, Xiu-Hua Chen, Yi-Rong Zheng, Hua Cao, Qiang Chen
Summary: This study aimed to investigate the feasibility and clinical outcomes of early enteral nutrition (EN) in critically ill neonates supported by extracorporeal membrane oxygenation (ECMO). The clinical data of 16 critically ill neonates who received ECMO support were retrospectively analyzed. The patients were divided into two groups: the early EN group (< 24 h) and the late EN group (> 24 h). The results showed that early EN was safe and practical for critically ill neonates receiving ECMO treatment, but close monitoring of clinical and nutritional indicators is essential.
Article
Cardiac & Cardiovascular Systems
Ernest G. Chan, Eric J. Hyzny, Masashi Furukawa, John P. Ryan, Kathirvel Subramaniam, Matthew R. Morrell, Joseph Pilewski, James D. Luketich, Pablo G. Sanchez
Summary: This study compared the outcomes of intraoperative venoarterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) during lung transplantation. The results showed that compared to the CPB group, the VA-ECMO group required fewer blood transfusions, had a shorter duration of mechanical ventilation, and had a lower incidence of grade 3 primary graft dysfunction at 72 hours. However, there were no differences in survival between the two groups.
ANNALS OF THORACIC SURGERY
(2023)
Article
Critical Care Medicine
Lindsay N. Shepard, Ron W. Reeder, Amanda O'Halloran, Martha Kienzle, Jameson Dowling, Kathryn Graham, Garrett P. Keim, Alexis A. Topjian, Nadir Yehya, Robert M. Sutton, Ryan W. Morgan
Summary: The aim of this study was to characterize respiratory failure prior to pediatric in-hospital cardiac arrest (IHCA) and to associate pre-arrest respiratory failure characteristics with survival outcomes. The study found substantial heterogeneity in respiratory failure characteristics and ventilatory requirements pre-arrest, and higher pre-arrest oxygen requirement and greater degree of oxygenation failure were associated with worse survival outcomes.
Article
Cardiac & Cardiovascular Systems
Dustin Hang, Kiran Chandrashekarappa, Kyle Schilling, Adam Ubert, Nilto de Oliveira, Paul S. Pagel
Summary: Venovenous extracorporeal membrane oxygenation (VV-ECMO) is increasingly used as a bridging strategy in decompensating patients awaiting lung transplantation. Various approaches for continuing support intraoperatively have been previously described. A two-circuit strategy that uses the in situ VV-ECMO circuit supplemented with peripheral cardiopulmonary bypass allows for diversion of native cardiac output away from the transplanted lung as well as seamless continuation of VV-ECMO postoperatively.
Article
Education & Educational Research
Jesus Lopez-Herce, Angel Carrillo, Javier Urbano, Gema Manrique, Santiago Mencia
Summary: Pediatric and neonatal CPR instructor courses are essential for training quality and homogeneity. Most participants passed the tests and evaluated the course positively.
BMC MEDICAL EDUCATION
(2021)
Article
Critical Care Medicine
Anoopindar K. Bhalla, Margaret J. Klein, Guillaume Emeriaud, Yolanda M. Lopez-Fernandez, Natalie Napolitano, Analia Fernandez, Awni M. Al-Subu, Rainer Gedeit, Steven L. Shein, Ryan Nofziger, Deyin Doreen Hsing, George Briassoulis, Stavroula Ilia, Florent Baudin, Byron Enrique Pineres-Olave, Ledys Maria Izquierdo, John C. Lin, Ira M. Cheifetz, Martin C. J. Kneyber, Lincoln Smith, Robinder G. Khemani, Christopher J. L. Newth
Summary: The study described mechanical ventilation management in pediatric acute respiratory distress syndrome and found that nonadherence to lung-protective ventilation principles is common, potentially impacting outcomes. Modifiable factors exist that may improve adherence.
CRITICAL CARE MEDICINE
(2021)
Review
Respiratory System
Pedro Reck dos Santos, Jonathan D'Cunha
Summary: Intraoperative mechanical support plays a crucial role during lung transplantation to maintain stable hemodynamic and ventilatory status, reducing the risk of suboptimal outcomes. Protective intraoperative management, along with thorough assessment of the donor, contributes to better surgical results.
JOURNAL OF THORACIC DISEASE
(2021)
Article
Cardiac & Cardiovascular Systems
Matthew Hartwig, Victor van Berkel, Ankit Bharat, Marcelo Cypel, Hiroshi Date, Michiel Erasmus, Konrad Hoetzenecker, Walter Klepetko, Zachary Kon, Jasleen Kukreja, Tiago Machuca, Kenneth McCurry, Olaf Mercier, Isabelle Opitz, Varun Puri, Dirk Van Raemdonck
Summary: The use of mechanical circulatory support (MCS) in lung transplantation has been steadily increasing, but there is significant practice variability. The AATS CPSC expert panel reviewed the existing literature and established 36 recommendations for the use of MCS in lung transplantation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Joshua B. Goldberg, Jay Giri, Taisei Kobayashi, Marc Ruel, Alexander J. C. Mittnacht, Belinda Rivera-Lebron, Abe DeAnda, John M. Moriarty, Thomas E. MacGillivray
Summary: Acute pulmonary embolism is a major cause of cardiovascular death, especially when it leads to acute right ventricular failure. Current guideline-directed therapy for hemodynamically compromised patients with pulmonary embolism has limited effectiveness in reducing mortality. Surgical embolectomy, once considered a last resort, has shown promising outcomes in treating acute pulmonary embolism, particularly in patients with hemodynamic instability. This document aims to describe modern surgical techniques, strategies, and outcomes, as well as suggest ways to further explore the role of surgery in the management of pulmonary embolisms.
Article
Endocrinology & Metabolism
S. Trivedi, A. Al-Nofal, S. Kumar, S. Tripathi, R. J. Kahoud, P. J. Tebben
OSTEOPOROSIS INTERNATIONAL
(2016)
Article
Anesthesiology
Manasi Hulyalkar, Stephen J. Gleich, Rahul Kashyap, Amelia Barwise, Harsheen Kaur, Yue Dong, Lei Fan, Srinivas Murthy, Grace M. Arteaga, Sandeep Tripathi
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2017)
Article
Critical Care Medicine
Harsheen Kaur, James M. Naessens, Andrew C. Hanson, Karen Fryer, Michael E. Nemergut, Sandeep Tripathi
JOURNAL OF INTENSIVE CARE MEDICINE
(2018)
Meeting Abstract
Critical Care Medicine
Marco Ayulo, Keri Phillips, Sandeep Tripathi
CRITICAL CARE MEDICINE
(2018)
Article
Critical Care Medicine
Marco Antonio Ayulo, Keri Ellen Phillips, Sandeep Tripathi
PEDIATRIC CRITICAL CARE MEDICINE
(2018)
Article
Critical Care Medicine
Gina M. Rohlik, Karen R. Fryer, Sandeep Tripathi, Julie M. Duncan, Heather L. Coon, Dipti R. Padhya, Robert J. Kahoud
CRITICAL CARE NURSE
(2018)
Article
Critical Care Medicine
Girish G. Deshpande, John E. Sanford, Sandeep Tripathi
Article
Acoustics
Sandeep Tripathi, Hammad Ganatra, Edmundo Martinez, Mohannad Mannaa, Joe Peters
JOURNAL OF CLINICAL ULTRASOUND
(2019)
Letter
Acoustics
Hammad Ganatra, Yanzhi Wang, Sandeep Tripathi
JOURNAL OF CLINICAL ULTRASOUND
(2019)
Article
Peripheral Vascular Disease
Sandeep Tripathi, Taylor Gladfelter
Summary: This study evaluated peripheral intravenous catheter insertion practices, finding that children had greater variation in catheter dwell time, lower failure rates compared to adults, but required more insertions during hospitalization. Factors influencing dwell time included discharge department, body part, and catheter size.
JOURNAL OF VASCULAR ACCESS
(2022)
Article
Pediatrics
Sandeep Tripathi, Jeremy S. Mcgarvey, Nadia Shaikh, Logan J. Meixsell
Summary: This study aims to describe and validate the flow index as a valid measure for assessing the degree of respiratory support in children on high flow nasal cannula (HFNC). The study found that the flow index had a significant correlation with length of stay in hospitals and escalation to the intensive care unit (ICU), and this correlation remained significant even after controlling for other factors. The categorization of flow index can predict the odds of hospital stay and escalation to the ICU in children.
JOURNAL OF PEDIATRIC INTENSIVE CARE
(2023)
Article
Pediatrics
Sandeep Tripathi, Tara Osman, Mina Hafzalah, Kejin Lee, Drew A. Whalen
Summary: This article assesses the correlation between respiratory variation in the inferior vena cava and central venous pressure in children, as well as its relation to clinical hydration status. The study found that the subcostal collapsibility index is the most reliable measure to assess the hydration status of spontaneously breathing children, while the inferior vena cava/aortic ratio performs well for patients under positive pressure.
JOURNAL OF PEDIATRIC INTENSIVE CARE
(2022)
Article
Critical Care Medicine
Sandeep Tripathi, Logan J. Meixsell, Michele Astle, Minchul Kim, Yamini Kapileshwar, Nabil Hassan
Summary: Patients who require escalation of care within 24 hours of hospital admission have longer ICU and hospital stays, and potentially increased cost of care.
JOURNAL OF INTENSIVE CARE MEDICINE
(2022)
Article
Pediatrics
Sandeep Tripathi, Venkedesh Raju, Kimberly A. Horack, Donna L. Bronson, Girish G. Deshpande
JOURNAL OF PEDIATRIC INTENSIVE CARE
(2018)