Nicardipine Inhibits Priming of the NLRP3 Inflammasome via Suppressing LPS-Induced TLR4 Expression

Rosmarinic Acid Mitigates Lipopolysaccharide-Induced Neuroinflammatory Responses through the Inhibition of TLR4 and CD14 Expression and NF-κB and NLRP3 Inflammasome Activation

(2018) Yicong Wei et al.   INFLAMMATION

Inhibition of myocardial hypertrophy by magnesium isoglycyrrhizinate through the TLR4/NF-κB signaling pathway in mice

(2018) Donglai Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting the NLRP3 inflammasome in inflammatory diseases

(2018) Matthew S. J. Mangan et al.   NATURE REVIEWS DRUG DISCOVERY

The phorbol 12-myristate-13-acetate differentiation protocol is critical to the interaction of THP-1 macrophages with Salmonella Typhimurium

(2018) Tregei Starr et al.   PLoS One

TLR4 absence reduces neuroinflammation and inflammasome activation in Parkinson’s diseases in vivo model

(2018) Michela Campolo et al.   BRAIN BEHAVIOR AND IMMUNITY

Verapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways

(2018) Feng Zhou et al.   Frontiers in Endocrinology

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness

(2017) Adeline M. Hajjar et al.   PLoS One

Effects of porcine MyD88 knockdown on the expression of TLR4 pathway-related genes and proinflammatory cytokines

(2016) C. Dai et al.   BIOSCIENCE REPORTS

Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice

(2016) Wenhan Wang et al.   INFLAMMATION

Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells

(2016) LU ZHAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation

(2016) Monica Molteni et al.   MEDIATORS OF INFLAMMATION

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis

(2015) Sean P. Cullen et al.   Cell Reports

Scropolioside B Inhibits IL-1βand Cytokines Expression through NF-κB and Inflammasome NLRP3 Pathways

(2014) Tiantian Zhu et al.   MEDIATORS OF INFLAMMATION

Anti-Neuroinflammatory Effects of the Calcium Channel Blocker Nicardipine on Microglial Cells: Implications for Neuroprotection

(2014) Bor-Ren Huang et al.   PLoS One

L-type calcium channel targeting and local signalling in cardiac myocytes

(2013) Robin M. Shaw et al.   CARDIOVASCULAR RESEARCH

Toll-Like Receptor 4–Mediated Nuclear Factor Kappa B Activation Is Essential for Sensing Exogenous Oxidants to Propagate and Maintain Oxidative/Nitrosative Cellular Stress

(2013) Rajendra Karki et al.   PLoS One

Antiinflammation Effect of Human Placental Multipotent Mesenchymal Stromal Cells Is Mediated by Prostaglandin E2 via a Myeloid Differentiation Primary Response Gene 88-dependent Pathway

(2012) Chie-Pein Chen et al.   ANESTHESIOLOGY

Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB

(2012) Sarada S.K.S. et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Calcium channel blockers and modulation of innate immunity

(2011) Wenling Liu et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

IL-27 Enhances LPS-Induced Proinflammatory Cytokine Production via Upregulation of TLR4 Expression and Signaling in Human Monocytes

(2011) C. Guzzo et al.   JOURNAL OF IMMUNOLOGY

Calcium Channel Blockers Differentially Modulate Cytokine Production by Peripheral Blood Mononuclear Cells

(2010) Akira Matsumori et al.   CIRCULATION JOURNAL

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

Differential Effects of Calcium-Channel Blockers on Vascular Endothelial Function in Patients With Coronary Spastic Angina

(2009) Yoichi Miwa et al.   CIRCULATION JOURNAL

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

(2009) N. B. Bryan et al.   JOURNAL OF IMMUNOLOGY