Article
Biochemistry & Molecular Biology
Mingzhe Wang, Wanyi Zhou, Ying Yang, Jianrong Xing, Xiaodan Xu, Yuqing Lin
Summary: The EPS derived from Lactobacillus pentosus strain YY-112 has beneficial effects on the intestinal microbiota and short-chain fatty acid production, making it a potential probiotic strain.
Article
Biochemistry & Molecular Biology
Mingkun Gu, Pia Werlinger, Joo-Hyung Cho, Nari Jang, Shin Sik Choi, Joo-Won Suh, Jinhua Cheng
Summary: This study established an obesity model of C. elegans by feeding them Enterobacter cloacae combined with a high glucose diet. Lactobacillus pentosus MJM60383 showed good antagonistic activity against E. cloacae and significantly reduced lipid accumulation in C. elegans, making it a promising candidate for anti-obesity probiotics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Microbiology
Odysseas Sotirios Stergiou, Konstantinos Tegopoulos, Despoina Eugenia Kiousi, Margaritis Tsifintaris, Aristotelis C. Papageorgiou, Chrysoula C. Tassou, Nikos Chorianopoulos, Petros Kolovos, Alex Galanis
Summary: The study analyzed the genome of the potential probiotic strain L. pentosus L33 isolated from fermented sausages, revealing its potential probiotic properties such as sensitivity to antibiotics and biosynthesis of exopolysaccharides. The strain also displayed adhesion properties and the absence of transferable antibiotic resistance genes, indicating its potential for medical and industrial applications.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Food Science & Technology
Jiali Wang, Chengshun Lu, Qiang Xu, Zhongyuan Li, Yajian Song, Sa Zhou, Le Guo, Tongcun Zhang, Xuegang Luo
Summary: The genome sequencing analysis of strain LTJ12 revealed it to be a potentially safe probiotic with high ethanol tolerance and alcohol metabolism. It belongs to the L. pentosus species. This study provides valuable insights into the accurate identification and rational application of Lactiplantibacillus species.
Article
Biochemistry & Molecular Biology
Fuli Zheng, Zhi Wang, Catherine Stanton, R. Paul Ross, Jianxin Zhao, Hao Zhang, Bo Yang, Wei Chen
Summary: In this study, it was found that strains of L. reuteri and L. rhamnosus significantly slowed weight gain in mice, alleviated blood glucose and lipid disorders, tissue damage, and gut microbiota disorders, produced SCFAs to induce satiety hormones, inhibit food intake, and increase satiety, ultimately improving metabolic syndrome.
Article
Microbiology
Mingkun Gu, Joo-Hyung Cho, Joo-Won Suh, Jinhua Cheng
Summary: In this study, Lactobacillus pentosus MJM60383 was identified as a potential oral probiotic that exhibits strong antagonistic activity against Streptococcus mutans. It possesses various probiotic properties and inhibits biofilm formation by S. mutans through the inhibition of glucan synthesis by glycosyltransferases.
JOURNAL OF ORAL MICROBIOLOGY
(2023)
Article
Food Science & Technology
Suwapat Kittibunchakul, Nantana Yuthaworawit, Kanyawee Whanmek, Uthaiwan Suttisansanee, Chalat Santivarangkna
Summary: This study developed a GABA drink by probiotic fermentation of brown rice milk, which contained high levels of GABA and probiotic cells, exhibited antioxidant activities, inhibited key enzymes related to obesity and diabetes, had good sensory acceptance with moderate calorie content, and could be refrigerated for up to 30 days. It has the potential to be commercialized as a plant-based functional drink with health benefits that may prevent chronic diseases.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Agriculture, Dairy & Animal Science
Giulia Bisson, Marilena Marino, Denise Poletti, Nadia Innocente, Michela Maifreni
Summary: This study examined the growth response and morphological changes of four probiotics under different environmental conditions, revealing variations in their stress tolerance. L. acidophilus was found to be the most sensitive strain, while L. plantarum showed better tolerance to a wide range of stressful conditions.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Food Science & Technology
Xuefei Shao, Miaomiao Zhu, Ziye Zhang, Pan Huang, Baocai Xu, Conggui Chen, Peijun Li
Summary: The study demonstrated that Lactobacillus pentosus R3 effectively reduces N-nitrosodimethylamine (NDMA) content in fermented sausages through various mechanisms, including direct degradation, indirect reduction of precursors, weakened oxidation, and decrease in non-haem iron content. This is achieved by inoculating the sausages with L. pentosus, which also improves microbial quality and inhibits NDMA formation.
Article
Microbiology
Qiqi Pan, Xudan Shen, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai
Summary: The study explored common functional genes for bile salt resistance in 90 Lactobacillus salivarius strains, identifying genes related to peptidoglycan synthesis, phosphotransferase system, and stress response as key factors. A significant association was found between GATase1-encoding gene and bile salt tolerance. Additionally, global regulatory genes for bile salt tolerance were identified, offering a potential method for rapid screening of bile salt-tolerant L. salivarius strains based on PCR amplification of functional genes.
Article
Biotechnology & Applied Microbiology
Ilenys M. Perez-Diaz, Suzanne D. Johanningsmeier, Kartheek Anekella, Christian G. Pagan-Medina, Lesley Mendez-Sandoval, Consuelo Arellano, Robert Price, Katheryne Daughtry, Michelle Borges, Chloe Bream, Lauren Connelly, Susan E. Dieck, Meredith T. Levi, Erin K. McMurtrie, Rickey E. Smith, Jeannette C. Theora, Paige Wendland, Francisco Gomez-Rodriguez, Francisco Noe Arroyo-Lopez
Summary: This study defined the genotypes of Lactobacillus plantarum and Lactobacillus pentosus in industrial-scale cucumber fermentations using rep-PCR-(GTG)5, and evaluated their ability to ferment cucumbers under various conditions. It was found that L. pentosus strains were more efficient in cucumber juice fermentation compared to most L. plantarum strains. This research identified genetically diverse L. pentosus strains and one L. plantarum strain as candidates for starter cultures in commercial cucumber fermentations.
Article
Biotechnology & Applied Microbiology
Xudong Liu, Zhinan Wu, Tongyuan Hu, Xiaoqian Lin, Hewei Liang, Wenxi Li, Xin Jin, Liang Xiao, Xiaodong Fang, Yuanqiang Zou
Summary: This study provides new insights into the genomic diversity analysis of L. acidophilus and uncovers the ecological adaptation of specific strains.
JOURNAL OF APPLIED MICROBIOLOGY
(2023)
Article
Food Science & Technology
Wanjing Lai, Rui Cai, Kang Yang, Tianli Yue, Zhenpeng Gao, Yahong Yuan, Zhouli Wang
Summary: This study aimed to screen probiotic strains for effective patulin control during juice fermentation. Among the six LAB strains tested, Lactobacillus pentosus (DSM 20314) showed the highest efficiency in removing patulin in apple juice, detoxifying 53.14% of the mycotoxin within 24 hours. The results indicate the potential of these probiotic strains in controlling patulin during apple juice fermentation and digestion.
Article
Biotechnology & Applied Microbiology
Esther Alonso Garcia, Nabil Benomar, Leyre Lavilla Lerma, Juan Jose de la Fuente Ordonez, Charles W. Knapp, Hikmate Abriouel
Summary: A study found that pre-adapting Lactiplantibacillus pentosus strains to vegetable-based edible oils significantly changed their susceptibility to antibiotics and induced gene expressions in some stress responses. This may provide a new approach for manufacturing probiotic products with improved stability, functionality, and robustness.
Article
Horticulture
Huaying Liu, Ruili Zhang, Qiuqin Zhang, Mengtian Tian, Xiaopu Ren, Libin Wang, Xiaohong Wang
Summary: This study aimed to evaluate the antimicrobial activity of cell-free supernatants (CFS) produced by Lactobacillus pentosus 86 against A. gaisen. Results showed that CFS displayed excellent thermos and enzymatic stabilities with an antifungal activity over 85%. CFS inhibited the mycelial growth of A. gaisen by destroying the hyphae membrane, leading to leakage of nucleic acids and proteins, collapse and shrinkage of hyphae, and changes in spore morphology.
Article
Biotechnology & Applied Microbiology
Zutan Li, Bingbing Jin, Jingya Fang
Summary: In this study, we propose MetaAc4C, an advanced deep learning model for accurate identification of N4-acetylcytidine (ac4C) sites using pre-trained BERT and various optimization techniques. By adapting generative adversarial networks to address data imbalance and augmenting training RNA samples, our model outperforms existing methods in terms of ACC, MCC, and AUROC.