Quantitative estimation of drug permeation through nasal mucosa using in vitro membrane permeability across Calu-3 cell layers for predicting in vivo bioavailability after intranasal administration to rats

Title
Quantitative estimation of drug permeation through nasal mucosa using in vitro membrane permeability across Calu-3 cell layers for predicting in vivo bioavailability after intranasal administration to rats
Authors
Keywords
Nasal absorption, Calu-3 cell line, Bioavailability, Mucosal absorption, Intranasal administration, Nasal formulation, Pharmacokinetics, In vitro, -, in vivo, correlation, PK modeling
Journal
Publisher
Elsevier BV
Online
2020-02-12
DOI
10.1016/j.ejpb.2020.02.004

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