Article
Chemistry, Analytical
Dominic A. M. J. Theuns, Sumant P. Radhoe, Jasper J. Brugts
Summary: Management of heart failure remains challenging despite advances in medical and pharmacological treatments. Strategies to reduce hospitalizations and readmission rates are urgently needed. Remote monitoring of high-risk patients, including those with cardiac implantable electronic devices, has shown promise in clinical practice for early identification of worsening heart failure.
Review
Medicine, General & Internal
Giuseppe Boriani, Jacopo F. Imberti, Niccolo Bonini, Cosimo Carriere, Davide A. Mei, Massimo Zecchin, Francesca Piccinin, Marco Vitolo, Gianfranco Sinagra
Summary: This review focuses on heart failure (HF) and its association with hospitalizations and adverse cardiovascular outcomes. The development of systems to monitor cardiac function aims to detect subclinical changes in order to prevent worsening HF. Patient-specific parameters can be remotely monitored through cardiac implantable electronic devices (CIED) and used to predict patients' risk of worsening HF. The review discusses the best diagnostic pathway for HF patients after a CIED alert and the role of healthcare professionals involved in HF patient management.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Antonio D'Onofrio, Francesco Solimene, Leonardo Calo, Valeria Calvi, Miguel Viscusi, Donato Melissano, Vitantonio Russo, Antonio Rapacciuolo, Andrea Campana, Fabrizio Caravati, Paolo Bonfanti, Gabriele Zanotto, Edoardo Gronda, Antonello Vado, Vittorio Calzolari, Giovanni Luca Botto, Massimo Zecchin, Luca Bontempi, Daniele Giacopelli, Alessio Gargaro, Luigi Padeletti
Summary: An algorithm was developed and validated to predict heart failure hospitalizations using remote monitoring data from implanted defibrillators. The study found that two-thirds of first post-implant heart failure hospitalizations could be predicted timely with a low false alert rate.
Article
Cardiac & Cardiovascular Systems
Ewa Jedrzejczyk-Patej, Michal Mazurek, Agnieszka Kotalczyk, Wiktoria Kowalska, Aleksandra Konieczny-Kozielska, Jonasz Kozielski, Tomasz Podolecki, Mariola Szulik, Adam Sokal, Oskar Kowalski, Zbigniew Kalarus, Beata Sredniawa, Radoslaw Lenarczyk
Summary: The study compared long-term mortality and predictors in patients with de novo cardiac resynchronization therapy defibrillators (CRT-D) versus those who upgraded from an implantable cardioverter-defibrillator (ICD) to CRT-D. It found that mortality was significantly higher in patients who upgraded from ICD to CRT-D compared to those who had de novo CRT-D implantations, with nearly 45% mortality within 4.5 years. A new CRT scale (Creatinine; Remodelling; Threshold for NYHA) was proposed to aid in predicting survival following CRT upgrade.
Article
Cardiac & Cardiovascular Systems
Camilla Sammut-Powell, Joanne K. Taylor, Manish Motwani, Catherine M. Leonard, Glen P. Martin, Fozia Zahir Ahmed
Summary: This study examined the association between Triage-HFRS algorithm in patients with cardiac implantable electronic devices and the risk of all-cause, cardiovascular, or heart failure hospitalization. The results showed that a high HFRS conferred a significantly higher relative risk of all-cause hospitalization, cardiovascular hospitalization, and heart failure hospitalization compared to a low Triage-HFRS.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Cheyenne S. L. Chiu, Ivy Timmermans, Henneke Versteeg, Edgar Zitron, Philippe Mabo, Susanne S. Pedersen, Mathias Meine
Summary: Remote patient monitoring (RPM) can be a viable alternative to conventional In-Clinic check-ups for implantable cardioverter-defibrillator (ICD) patients. This study found that RPM is non-inferior to In-Clinic visits in terms of clinical outcomes. RPM can reduce unnecessary clinic visits without compromising safety and efficiency.
Article
Cardiac & Cardiovascular Systems
Henrike A. K. Hillmann, Claudius Hansen, Oliver Przibille, David Duncker
Summary: This study aims to analyze the patient perspectives on the remote monitoring of cardiac devices in Germany. The survey found that most patients felt well informed and remote monitoring helped them cope with their disease. Some patients experienced technical problems with remote monitoring, and younger patients are more interested in using smartphones for data transfer.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Giuseppe Boriani, Haran Burri, Emma Svennberg, Jacopo Francesco Imberti, Jose Luis Merino, Christophe Leclercq
Summary: Remote monitoring is recommended as a standard care for the follow-up of CIEDs, as it can detect issues and changes in cardio-respiratory functions. However, the heterogeneity in reimbursement policies across Europe is a significant barrier to widespread implementation.
Article
Cardiac & Cardiovascular Systems
Maarten Z. H. Kolk, Sanjiv M. Narayan, Paul Clopton, Arthur A. M. Wilde, Reinoud E. Knops, Fleur V. Y. Tjong
Summary: Remote monitoring for ICDs can detect disease progression and device dysfunction early. This study found that in a real-world population, remote monitoring was associated with a reduction in all-cause and cardiac mortality compared to traditional office visits.
Article
Health Care Sciences & Services
Gimon de Graaf, Ivy Timmermans, Mathias Meine, Marco Alings, Susanne S. Pedersen, Philippe Mabo, Edgar Zitron, Ken Redekop, Henneke Versteeg
Summary: Remote patient monitoring of heart failure patients with an implantable cardioverter defibrillator can reduce medical resource use and travel time. In the Netherlands and Germany, remote monitoring led to lower direct medical costs, with varying effectiveness for patients.
JOURNAL OF TELEMEDICINE AND TELECARE
(2022)
Article
Cardiac & Cardiovascular Systems
Jeroen Dauw, Pieter Martens, Petra Nijst, Evelyne Meekers, Sebastien Deferm, Henri Gruwez, Maximo Rivero-Ayerza, Hugo Van Herendael, Laurent Pison, Dieter Nuyens, Matthias Dupont, Wilfried Mullens
Summary: The aim of this study was to evaluate the predictive ability of the MADIT-ICD benefit score in identifying heart failure patients who would benefit most from CRT-D and compare it with a multidisciplinary expert centre approach. The results showed that the MADIT-ICD benefit score can identify patients who would benefit most from CRT-D and its predictive power is comparable to multidisciplinary judgement.
Article
Cardiac & Cardiovascular Systems
Derek S. Chew, Mahmood Zarrabi, Isabelle You, James Morton, Aaron Low, Lucy Reyes, Brian Yuen, Glen L. Sumner, Satish R. Raj, Derek Exner, Stephen B. Wilton
Summary: This study demonstrates that remote monitoring (RM) of cardiac implantable electronic devices is associated with lower risk of death and cardiovascular hospitalization, and can lead to cost savings. Therefore, the wider implementation of this technology can improve patient outcomes and enhance health system efficiency.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Boglarka Veres, Walter Richard Schwertner, Marton Tokodi, Adam Szijarto, Attila Kovacs, Eperke Dora Merkel, Anett Behon, Luca Kuthi, Richard Masszi, Laszlo Geller, Endre Zima, Levente Molnar, Istvan Osztheimer, David Becker, Annamaria Kosztin, Bela Merkely
Summary: Topological data analysis (TDA) can identify phenogroups of CRT patients in whom CRT-D is associated with better survival than CRT-P.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Meor Azraai, Daisuke Miura, Yuan-Hong Lin, Thalys Sampaio Rodrigues, Voltaire Nadurata
Summary: This study investigated the incidence and predictors of cardiac implantable electronic device (CIED) malfunction with radiotherapy (RT). The study found that photon beam energy ≥10 MV, anatomical location of RT above the diaphragm, and having a CIED from the ICD group were predictors of CIED malfunction.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Xu Gao, Mohamad Abdi, Daniel A. Auger, Changyu Sun, Christopher A. Hanson, Austin A. Robinson, Christopher Schumann, Pim J. Oomen, Sarah Ratcliffe, Rohit Malhotra, Andrew Darby, Oliver J. Monfredi, J. Michael Mangrum, Pamela Mason, Sula Mazimba, Jeffrey W. Holmes, Christopher M. Kramer, Frederick H. Epstein, Michael Salerno, Kenneth C. Bilchick
Summary: This study aimed to investigate the feasibility and effectiveness of CMR cine and strain imaging before and after CRT for assessing patient response and determining the optimal resynchronization pacing strategy. The results showed that CMR evaluation with assessment of multiple pacing modes after CRT is feasible and provides valuable information for patient care.
JACC-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Justyna Jankowska-Sanetra, Krzysztof Sanetra, Marta Konopko, Monika Kutowicz, Magdalena Synak, Krzysztof Milewski, Pawel Kazmierczak, Lukasz Koltowski, Piotr Pawel Buszman
Summary: This study investigated the baseline characteristics, treatment, and outcomes of stable coronary disease patients after the first wave of the COVID-19 pandemic. A comparison was made with patients from the same period in 2019. The results showed that the number of hospitalized stable patients decreased after the lockdown, they were younger and had more comorbidities, and there were changes in treatment, but no significant differences in hospitalization outcomes. The higher prevalence of comorbidities raises concerns for the future.
CARDIOLOGY JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Zbigniew Kalarus, Georges H. Mairesse, Adam Sokal, Giuseppe Boriani, Beata Sredniawa, Ruben Casado Arroyo, Rolf Wachter, Gerrit Frommeyer, Vassil Traykov, Nikolaos Dagres, Gregory Y. H. Lip, Lucas Boersma, Petr Peichl, Dobromir Dobrev, Alan Bulava, Carina Blomstrom-Lundqvist, Natasja M. S. de Groot, Renate Schnabel, Frank Heinzel, Isabelle C. Van Gelder, Corrado Carbuccichio, Dipen Shah, Lars Eckardt
Article
Medicine, Research & Experimental
Emilia Bleszynska-Marunowska, Lukasz Wierucki, Kacper Jagiello, Krzysztof Rewiuk, Katarzyna Mitrega, Zbigniew Kalarus
Summary: This study identified a high prevalence of potential drug interactions in the Polish geriatric population. Automated analysis systems deliver useful information on pharmacological interactions and should be promoted in the Polish healthcare community as tools to support pharmacotherapy.
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Andrzej Kutarski, Maria Miszczak-Knecht, Monika Brzezinska, Mariusz Birbach, Wojciech Lipinski, Aneta Maria Polewczyk, Wojciech Jachec, Anna Polewczyk, Lukasz Tulecki, Konrad Tomkow, Pawel Stefanczyk, Dorota Nowosielecka, Katarzyna Bieganowska
Summary: This study compared the differences in trans-venous lead extraction (TLE) between children and adults with cardiac implantable electronic devices (CIED). The results showed that TLE in children had longer operation time, more technical difficulties, and lower success rate. This is due to the formation of strong fibrous tissue surrounding the leads in pediatric patients.
CIRCULATION JOURNAL
(2023)
Article
Environmental Sciences
Pawel Stefanczyk, Dorota Nowosielecka, Anna Polewczyk, Wojciech Jachec, Andrzej Glowniak, Jaroslaw Kosior, Andrzej Kutarski
Summary: This study aimed to assess the complexity, risk, and outcome of transvenous lead extraction (TLE) among patients undergoing pacemaker upgrade to ICDs and CRTs. The results showed that TLE was the leading indication for upgrade in only 36-66% of patients, and the success rate of the upgrade procedure was 42.0-57.6%. Overall, the long-term survival rate was lower in the CRT-upgrade group compared to the non-upgrade group.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Monika Budnik, Monika Gawalko, Piotr Lodzinski, Agata Tyminska, Krzysztof Ozieranski, Marcin Grabowski, Michal Peller, Anna Wancerz, Marek Kiliszek, Grzegorz Opolski, Radoslaw Lenarczyk, Zbigniew Kalarus, Gregory Y. H. Lip, Pawel Balsam
Summary: Heart failure has a significant impact on clinical outcomes in atrial fibrillation patients, leading to higher mortality rates and more frequent cardiovascular interventions and events. There is no statistically significant difference in long-term outcomes among different types of heart failure.
Editorial Material
Cardiac & Cardiovascular Systems
Mateusz Tajstra, Krzysztof Wilczek, Lukasz Pyka, Mariusz Gasior
KARDIOLOGIA POLSKA
(2023)
Review
Medicine, Research & Experimental
Karolina Ewa Chodor-Rozwadowska, Magdalena Sawicka, Stanislaw Morawski, Radoslaw Lenarczyk, Zbigniew Kalarus, Tomasz Kukulski
Summary: The implantation of cardiac implantable electronic devices (CIEDs) may lead to or worsen tricuspid regurgitation (TR). The prevalence of lead-related tricuspid regurgitation (LRTR) in patients with CIEDs ranges from 7.2% to 44.7% when the worsening degree of TR is not reported, or from 9.8% to 38% when it is diagnosed as worsening of TR severity by at least 2 grades after a CIED has been implanted. It has been suggested that the positioning of a CIED lead over or pinning a leaflet may be the main cause of TR in these patients.
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
(2023)
Article
Medicine, General & Internal
Andrzej Kutarski, Wojciech Jachec, Dorota Nowosielecka, Anna Polewczyk
Summary: In 18.43% of the 3721 TLE procedures, unexpected difficulties including lead venous blockage, lead dislodgement, and broken lead fragment occurred. These difficulties were mostly associated with long lead dwell time, younger patient age, lead burden, and poor procedure effectiveness. However, some problems seemed to be related to cardiac implantable electronic device (CIED) implantation and subsequent lead management strategy.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Andrzej Kutarski, Wojciech Jachec, Anna Polewczyk, Dorota Nowosielecka
Summary: This retrospective analysis of 3741 patients who underwent transvenous lead extraction (TLE) found that 4.17% had non-removable lead remnants (LR). Younger age, multiple CIED procedures, and higher procedure complexity were identified as independent risk factors for LR retention, while CIED infection did not influence LR presence. Although patients with LR showed better survival outcomes following TLE, multivariable Cox regression analysis did not confirm the prognostic significance of LR.
JOURNAL OF CLINICAL MEDICINE
(2023)
Letter
Cardiac & Cardiovascular Systems
Maciej Dyrbus, Mariusz Gasior, Mateusz Tajstra
Article
Biochemistry & Molecular Biology
Jolanta Malinowska-Borowska, Marta Buczkowska, Sylwia Duda, Apolonia Stefaniak, Jacek Niedziela, Jolanta Urszula Nowak, Jadwiga Nessler, Karol Adam Kaminski, Mariusz Gasior, Piotr Rozentryt
Summary: Heart failure is a highly heterogeneous syndrome, and the heterogeneity of skeletal muscle quantity and function may have an impact on patient's phenotype. In this study, clinical characteristics of different phenotypes defined by a combination of skeletal muscle mass and urinary creatinine levels were compared. The phenotype with low skeletal muscle mass and low urinary creatinine levels was associated with the highest mortality, and this risk was not captured by the MAGGIC score. Measurement of urinary creatinine can serve as a potentially useful biomarker to phenotype heart failure patients independently of their skeletal muscle status.
Article
Medicine, General & Internal
Marta Bujak, Aneta Desperak, Marek Gierlotka, Krzysztof Milewski, Krystian Wita, Zbigniew Kalarus, Joanna Fluder-Wlodarczyk, Pawel Pawlus, Pawel E. Buszman, Jacek Piegza, Wojciech Wojakowski, Pawel Gasior
Summary: This study analyzed data from 82,235 STEMI patients treated with primary PCI and found that smoking was associated with better clinical outcomes. However, after adjustment for baseline characteristics, smoking was found to be one of the independent risk factors for 36-month mortality.
POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ
(2023)
Article
Cardiac & Cardiovascular Systems
Justyna Jankowska-Sanetra, Krzysztof Sanetra, Marta Konopko, Monika Kutowicz, Magdalena Synak, Pawel Kazmierczak, Krzysztof Milewski, Lukasz Koltowski, Piotr Pawel Buszman
Summary: The COVID-19 pandemic has had a significant impact on cardiovascular disease patients, particularly those with acute coronary syndrome (ACS). Lockdown measures have led to treatment-related concerns and reluctance to seek medical help, resulting in delayed treatment. Analysis of ACS incidence and course after the first wave of COVID-19 showed an increase in cardiovascular risk factors among patients, as well as changes in treatment modalities and an increased risk of mortality.
KARDIOLOGIA POLSKA
(2023)
Article
Medicine, Research & Experimental
Emilia Bleszynska-Marunowska, Lukasz Wierucki, Kacper Jagiello, Krzysztof Rewiuk, Katarzyna Mitrega, Zbigniew Kalarus
Summary: Due to advanced age, multimorbidity, and polypharmacotherapy, older patients in the Polish geriatric population are predisposed to drug interactions. This study found a high prevalence of potential drug interactions, with multimorbidity being the most important predisposing factor. Automated analysis systems prove to be useful tools in providing pharmacological interaction information to support pharmacotherapy.
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
(2023)