Active and adaptiveLegionellaCRISPR-Cas reveals a recurrent challenge to the pathogen

Legionella pneumophila, armed to the hilt: justifying the largest arsenal of effectors in the bacterial world

(2016) Alexander W Ensminger   CURRENT OPINION IN MICROBIOLOGY

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System

(2015) Sy Redding et al.   CELL

I can see CRISPR now, even when phage are gone

(2015) Hannah K. Ratner et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Subtyping of the Legionella pneumophila “Ulm” outbreak strain using the CRISPR–Cas system

(2015) Christian Lück et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Prevalence of Protozoa Species in Drinking and Environmental Water Sources in Sudan

(2015) Salah Shanan et al.   Biomed Research International

Prokka: rapid prokaryotic genome annotation

(2014) T. Seemann   BIOINFORMATICS

Nuclease Activity of Legionella pneumophila Cas2 Promotes Intracellular Infection of Amoebal Host Cells

(2014) Felizza F. Gunderson et al.   INFECTION AND IMMUNITY

Soil as a source of Legionella pneumophila sequence type 47

(2014) Johanna A.C. Schalk et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

ViableLegionella pneumophilabacteria in natural soil and rainwater puddles

(2014) E. van Heijnsbergen et al.   JOURNAL OF APPLIED MICROBIOLOGY

Adapting to new threats: the generation of memory by CRISPR-Cas immune systems

(2014) Robert Heler et al.   MOLECULAR MICROBIOLOGY

Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates

(2014) Leonor Sánchez-Busó et al.   NATURE GENETICS

Unravelling the structural and mechanistic basis of CRISPR–Cas systems

(2014) John van der Oost et al.   NATURE REVIEWS MICROBIOLOGY

Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer

(2014) Corinna Richter et al.   NUCLEIC ACIDS RESEARCH

Degenerate target sites mediate rapid primed CRISPR adaptation

(2014) P. C. Fineran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa

(2014) A. Pawluk et al.   mBio

Integrative Conjugative Element ICE- ox Confers Oxidative Stress Resistance to Legionella pneumophila In Vitro and in Macrophages

(2014) K. J. Flynn et al.   mBio

Mining and assessment of catabolic pathways in the metagenome of a common effluent treatment plant to induce the degradative capacity of biomass

(2013) Ravi P. More et al.   BIORESOURCE TECHNOLOGY

Efficient and accurate whole genome assembly and methylome profiling of E. coli

(2013) Jason G Powers et al.   BMC GENOMICS

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

A CRISPR/Cas system mediates bacterial innate immune evasion and virulence

(2013) Timothy R. Sampson et al.   NATURE

Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data

(2013) Chen-Shan Chin et al.   NATURE METHODS

Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process

(2013) Ming Li et al.   NUCLEIC ACIDS RESEARCH

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

(2013) Ines Fonfara et al.   NUCLEIC ACIDS RESEARCH

Phylogenetic Reconstruction of the Legionella pneumophila Philadelphia-1 Laboratory Strains through Comparative Genomics

(2013) Chitong Rao et al.   PLoS One

A Distinct and Divergent Lineage of Genomic Island-Associated Type IV Secretion Systems in Legionella

(2013) Bryan A. Wee et al.   PLoS One

Surface display of a massively variable lipoprotein by a Legionella diversity-generating retroelement

(2013) D. Arambula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRISPRTarget

(2013) Ambarish Biswas et al.   RNA Biology

The CRISPR-Associated Gene cas2 of Legionella pneumophila Is Required for Intracellular Infection of Amoebae

(2013) F. F. Gunderson et al.   mBio

The CRISPR/Cas Adaptive Immune System of Pseudomonas aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages

(2012) K. C. Cady et al.   JOURNAL OF BACTERIOLOGY

CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

(2012) Edze R. Westra et al.   MOLECULAR CELL

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system

(2012) Joe Bondy-Denomy et al.   NATURE

RNA-guided genetic silencing systems in bacteria and archaea

(2012) Blake Wiedenheft et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli

(2012) Ido Yosef et al.   NUCLEIC ACIDS RESEARCH

Aggravating Genetic Interactions Allow a Solution to Redundancy in a Bacterial Pathogen

(2012) T. J. O'Connor et al.   SCIENCE

Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system

(2012) Kirill A. Datsenko et al.   Nature Communications

Experimental Evolution of Legionella pneumophila in Mouse Macrophages Leads to Strains with Altered Determinants of Environmental Survival

(2012) Alexander W. Ensminger et al.   PLoS Pathogens

PGAP: pan-genomes analysis pipeline

(2011) Yongbing Zhao et al.   BIOINFORMATICS

Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes

(2011) Laura Gomez-Valero et al.   BMC GENOMICS

BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons

(2011) Nabil-Fareed Alikhan et al.   BMC GENOMICS

Evolution and classification of the CRISPR–Cas systems

(2011) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion

(2011) T. J. O'Connor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

(2011) E. Semenova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Regulatory RNA and Legionella pneumophila

(2011) Sébastien P. Faucher et al.   Frontiers in Microbiology

Legionella pneumophila pangenome reveals strain-specific virulence factors

(2010) Giuseppe D'Auria et al.   BMC GENOMICS

E3 Ubiquitin Ligase Activity and Targeting of BAT3 by Multiple Legionella pneumophila Translocated Substrates

(2010) A. W. Ensminger et al.   INFECTION AND IMMUNITY

Legionella pneumophila Strain 130b Possesses a Unique Combination of Type IV Secretion Systems and Novel Dot/Icm Secretion System Effector Proteins

(2010) G. N. Schroeder et al.   JOURNAL OF BACTERIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

ABySS: A parallel assembler for short read sequence data

(2009) J. T. Simpson et al.   GENOME RESEARCH

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

(2009)   MICROBIOLOGY-SGM

Passage through Tetrahymena tropicalis Triggers a Rapid Morphological Differentiation in Legionella pneumophila

(2008) G. Faulkner et al.   JOURNAL OF BACTERIOLOGY

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

(2008) S. J. J. Brouns et al.   SCIENCE

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

(2008) Luciano A. Marraffini et al.   SCIENCE

Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands

(2007) Gernot Glöckner et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY