Article
Environmental Sciences
P. A. Bommarito, A. Friedman, B. M. Welch, D. E. Cantonwine, M. Ospina, A. M. Calafat, J. D. Meeker, T. F. Mcelrath, K. K. Ferguson
Summary: This study investigated the temporal trends and predictors of OPE exposure in pregnant women from 2007 to 2018. The results showed that concentrations of most OPE biomarkers varied according to sociodemographic factors, suggesting higher burdens of exposure among participants with higher pre-pregnancy BMI, those belonging to racial and ethnic minority populations, and lower educational attainment.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Weili Yang, Joseph M. Braun, Ann M. Vuong, Zana Percy, Yingying Xu, Changchun Xie, Ranjan Deka, Antonia M. Calafat, Maria Ospina, Heather H. Burris, Kimberly Yolton, Kim M. Cecil, Bruce P. Lanphear, Aimin Chen
Summary: Organophosphate esters (OPEs) have been found to be developmental toxicants in animal studies, but limited evidence is available in humans. This study investigated the association between gestational exposure to OPEs and gestational age, preterm birth, and newborn anthropometric measures. The findings suggest that certain OPEs may be associated with these outcomes, with some associations being specific to certain time windows and infant sex.
ENVIRONMENTAL POLLUTION
(2023)
Article
Nutrition & Dietetics
Dominika Mazurkiewicz, Monika Bronkowska
Summary: The study focused on assessing the relationships between maternal insulin and IGF-1 concentration, food consumption frequency, and newborn birth parameters. It found that frequent consumption of sweet and salty snacks, as well as fruit and fruit or vegetable juices, may lead to greater weight gain in pregnancy and higher newborn birth weight. Additionally, the study showed that overweight women had higher insulin concentrations and women over 35 years old had lower concentrations of IGF-1.
Article
Multidisciplinary Sciences
Samson Gebremedhin, Tilahun Bekele
Summary: In sub-Saharan Africa, pregnant women on average gain inadequate weight (6.6 kg) over pregnancy, with the most significant weight gain occurring in the second and third trimesters. Women with higher education and from wealthier households tend to have higher gestational weight gain. Recent data does not show significant improvements in gestational weight gain in sub-Saharan Africa.
Article
Environmental Sciences
Hongxiu Liu, Anna Maria Campana, Yuyan Wang, Kurunthachalam Kannan, Mengling Liu, Hongkai Zhu, Shilpi Mehta-Lee, Sara G. Brubaker, Linda G. Kahn, Leonardo Trasande, Akhgar Ghassabian
Summary: The study found that pregnant women in NYC had lower levels of OP pesticide metabolites than pregnant populations in Europe, Asia, and other regions in the U.S. Lower pre-pregnancy body mass index, being Asian, employed, and single were associated with higher DAP metabolite concentrations, while fruit and grain intakes were associated with higher Sigma DM, Sigma DE, and Sigma DAP levels.
ENVIRONMENTAL POLLUTION
(2021)
Article
Endocrinology & Metabolism
Robin Schuerfeld, Ekaterine Baratashvili, Marleen Wuerfel, Matthias Blueher, Michael Stumvoll, Anke Toenjes, Thomas Ebert
Summary: This study investigated the regulation of ACBP in women with gestational diabetes mellitus (GDM) during pregnancy and postpartum. The results showed that ACBP levels decreased during pregnancy and increased after pregnancy, and ACBP was related to beta cell function and renal markers.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Arash Derakhshan, Tuija Mannisto, Liangmiao Chen, Joris A. J. Osinga, Ghalia Ashoor, Xuemian Lu, Sofie Bliddal, Fang-Biao Tao, Suzanne J. Brown, Bijay Vaidya, Andrew T. Hattersley, Sachiko Itoh, Polina Popova, Ashraf Aminorroaya, Reiko Kishi, Maryam Kianpour, Elena A. Vasukova, Abel Lopez-Bermejo, Emily Oken, Leda Chatzi, Marina Vafeiadi, Wichor M. Bramer, Judit Bassols, Aitana Lertxundi, Ana Fernandez-Somoano, Paula Carrasco, Juha Auvinen, Kun Huang, Ulla Feldt-Rasmussen, Elena N. Grineva, Erik K. Alexander, Elizabeth N. Pearce, Layal Chaker, John P. Walsh, Robin P. Peeters, Monica Guxens, Eila Suvanto, Kypros H. Nicolaides, Tim I. M. Korevaar
Summary: This study explores the association between gestational FT3 and TT3 levels and adverse obstetric outcomes. The findings suggest that FT3 and TT3 levels have different associations with various adverse obstetric outcomes, with high TT3 associated with an increased risk of gestational hypertension and low TT3 associated with a higher risk of very preterm birth.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Biochemistry & Molecular Biology
Arpita Basu, Jeannette Crew, Jeffrey L. Ebersole, Jefferson W. Kinney, Arnold M. Salazar, Petar Planinic, James M. Alexander
Summary: The study showed that a dietary intervention including whole blueberries and soluble fiber during pregnancy can significantly increase maternal serum glutathione and antioxidant capacity, decrease malondialdehyde levels, and reduce adipocyte dysfunction and insulin resistance biomarkers.
Article
Reproductive Biology
Sumitaka Kobayashi, Fumihiro Sata, Atsuko Ikeda-Araki, Chihiro Miyashita, Houman Goudarzi, Yusuke Iwasaki, Tamie Nakajima, Reiko Kishi
Summary: This study assessed the associations between PFOS and PFOA levels, maternal genotypes, and birth outcomes. The results showed that interactions between PFOS levels and the maternal genotype of LXRB affected birth size in female infants.
REPRODUCTIVE TOXICOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Amber M. Hall, Amanda M. Ramos, Samantha SM. Drover, Giehae Choi, Alexander P. Keil, David B. Richardson, Chantel L. Martin, Andrew F. Olshan, Gro D. Villanger, Ted Reichborn-Kjennerud, Pal Zeiner, Kristin R. overgaard, Amrit K. Sakhi, Cathrine Thomsen, Heidi Aase, Stephanie M. Engel
Summary: This study found a modest increased odds of preschool ADHD with higher DnBP and BDCIPP exposure.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Endocrinology & Metabolism
Ravi Retnakaran, Chang Ye, Anthony J. Hanley, Philip W. Connelly, Mathew Sermer, Bernard Zinman, Jill K. Hamilton
Summary: Despite reducing birth weight and macrosomia, the treatment of GDM does not have analogous effects on infant adiposity across the 1st year of life.
Article
Anthropology
Jorge Martinez, Gabriela B. Revollo, Emma L. Alfaro, Carlos Grandi, Jose E. Dipierri
Summary: This study evaluated the nutritional status of newborns in highland and lowland regions, finding that the lowland sample had significantly higher PRI values than the highland sample. Regardless of altitude and gestational age, BMI was preferred as the indicator for evaluating nutritional status.
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2021)
Article
Medicine, General & Internal
Rachel D'Amico, Djhenne Dalmacy, Jenifer A. Akinduro, Madison Hyer, Stephen Thung, Shengyi Mao, Naleef Fareed, Seuli Bose-Brill
Summary: Gestational diabetes (GD) affects pregnancy and increases the risk of type 2 diabetes. The study aimed to explore how often individuals with GD access primary care and type 2 diabetes screening.
Article
Multidisciplinary Sciences
Wonjin Kim, Soo Kyung Park, Yoo Lee Kim
Summary: The study found that fetal abdominal obesity (FAO) is present in older and/or obese pregnant women with gestational diabetes mellitus (GDM) at the time of diagnosis and persists until delivery. GDM patients with FAO at 20-24 weeks have a significantly higher likelihood of being diagnosed with GDM and giving birth to large for gestational age babies, as well as a higher rate of primary cesarean delivery compared to those without FAO. Early diagnosis and intervention of GDM before 20-24 weeks may be necessary to prevent FAO in older and/or obese women.
SCIENTIFIC REPORTS
(2021)
Review
Biochemistry & Molecular Biology
Jorge Valencia-Ortega, Rebeca Gonzalez-Reynoso, Edgar G. Ramos-Martinez, Aldo Ferreira-Hermosillo, Maria I. Pena-Cano, Enrique Morales-avila, Renata Saucedo
Summary: Gestational diabetes mellitus (GDM) is a common metabolic disorder during pregnancy with significant impact on the health of both mother and newborn. Recent research has focused on the expression levels and circulating characteristics of adipokines in different tissues of GDM patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Yun Liu, Melissa N. Eliot, George D. Papandonatos, Karl T. Kelsey, Ruby Fore, Scott Langevin, Jessie Buckley, Aimin Chen, Bruce P. Lanphear, Kim M. Cecil, Kimberly Yolton, Marie-France Hivert, Sharon K. Sagiv, Andrea A. Baccarelli, Emily Oken, Joseph M. Braun
Summary: In this study, we examined the associations between gestational PFAS exposure and DNA methylation levels at birth and in adolescence using longitudinal data. The results showed that gestational PFAS exposure was associated with differences in several CpG sites at birth and at 12 years of age, which were linked to genes associated with PFAS-related health outcomes.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Article
Engineering, Environmental
Jessie P. Buckley, Jordan R. Kuiper, Deborah H. Bennett, Emily S. Barrett, Tracy Bastain, Carrie Breton, Sridhar Chinthakindi, Anne L. Dunlop, Shohreh F. Farzan, Julie B. Herbstman, Margaret R. Karagas, Carmen J. Marsit, John D. Meeker, Rachel Morello-Frosch, Thomas G. O'Connor, Megan E. Romano, Susan Schantz, Rebecca J. Schmidt, Deborah J. Watkins, Hongkai Zhu, Edo D. Pellizzari, Kurunthachalam Kannan, Tracey J. Woodruff
Summary: Prenatal chemical exposures can affect maternal and child health, but routine biomonitoring does not cover many industrial chemicals. A study of 171 pregnant women in the US and Puerto Rico found widespread exposures to both common and understudied chemicals in this diverse population, with higher concentrations of certain chemicals in Hispanic women.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Editorial Material
Endocrinology & Metabolism
Jessie P. Buckley
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Environmental Sciences
Joseph M. Braun, George D. Papandonatos, Nan Li, Clara G. Sears, Jessie P. Buckley, Kim M. Cecil, Aimin Chen, Charles B. Eaton, Heidi J. Kalkwarf, Karl T. Kelsey, Bruce P. Lanphear, Kimberly Yolton
Summary: In this cohort, physical activity during adolescence modified the association between prenatal serum PFOA concentrations and cardiometabolic risk in children, suggesting that lifestyle interventions may alleviate the adverse effects of PFOA exposure. However, diet did not modify any associations.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Taylor M. Etzel, Joseph M. Braun, Jordan R. Kuiper, Antonia M. Calafat, Kim M. Cecil, Aimin Chen, Bruce P. Lanphear, Kimberly Yolton, Heidi J. Kalkwarf, Jessie P. Buckley
Summary: This study suggests that early life exposure to certain phthalates may be associated with body composition, particularly lean mass, during adolescence.
ENVIRONMENTAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Julie B. Herbstman, Megan E. Romano, Xiuhong Li, Lisa P. Jacobson, Amy E. Margolis, Ghassan B. Hamra, Deborah H. Bennett, Joseph M. Braun, Jessie P. Buckley, Trina Colburn, Sean Deoni, Lori A. Hoepner, Rachel Morello-Frosch, Kylie Wheelock Riley, Sheela Sathyanarayana, Susan L. Schantz, Leonardo Trasande, Tracey J. Woodruff, Frederica P. Perera, Margaret R. Karagas
Summary: The COVID-19 pandemic and its restrictions have led to changes in behaviors that can influence environmental exposures. Environmental exposures and psychological stress have been found to contribute to adverse child health outcomes. A survey conducted in the ECHO-wide Cohort revealed pandemic-related behavior changes associated with environmental exposures.
Article
Environmental Sciences
Nerea Mourino, Monica Perez-Rios, Kimberly Yolton, Bruce P. Lanphear, Aimin Chen, Jessie P. Buckley, Heidi J. Kalkwarf, Kim M. Cecil, Joseph M. Braun
Summary: This study found that postnatal serum cotinine concentrations had a greater influence on adolescent's cardiometabolic risk compared to the prenatal period, and these associations may be sex-specific.
ENVIRONMENTAL RESEARCH
(2023)
Article
Engineering, Environmental
Lydia M. Louis, Jessie P. Buckley, Jordan R. Kuiper, John D. Meeker, Nadia N. Hansel, Meredith C. McCormack, Gregory Diette, Lesliam Quiros-Alcala
Summary: This study investigates the associations between urinary biomarkers of organophosphate esters (OPEs) and symptoms of respiratory morbidity in children with asthma. The findings suggest that certain OPEs are associated with respiratory symptoms, but further research is needed to confirm causality.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jordan R. Kuiper, Shudi Pan, Bruce P. Lanphear, Antonia M. Calafat, Aimin Chen, Kim M. Cecil, Yingying Xu, Kimberly Yolton, Heidi J. Kalkwarf, Joseph M. Braun, Jessie P. Buckley
Summary: Background: Early life environmental exposures may affect bone mass accrual in childhood, but only limited research has been done on the role of environmental phenols in child bone health. This study found weak associations between the concentrations of environmental phenols and bone mineral content and density, suggesting the need for further research on the mechanisms of this effect.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Taylor M. Etzel, Jordan R. Kuiper, Xiaobin Wang, Noel T. Mueller, Antonia M. Calafat, Kim M. Cecil, Aimin Chen, Bruce P. Lanphear, Kimberly Yolton, Heidi J. Kalkwarf, Joseph M. Braun, Jessie P. Buckley
Summary: A prospective study found that early-life phthalate exposures may affect cardiometabolic outcomes during adolescence. The concentrations of nine phthalate metabolites in urine samples collected during pregnancy and childhood were associated with cardiometabolic biomarkers at age 12, with differences observed between males and females.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Environmental Sciences
Harry Sultan, Jessie P. Buckley, Heidi J. Kalkwarf, Kim M. Cecil, Aimin Chen, Bruce P. Lanphear, Kimberly Yolton, Joseph M. Braun
Summary: This study investigated the relationship between dietary quality and macronutrient intake with serum PFAS concentrations in US adolescents, and found that higher dietary quality and dietary fiber intake were associated with lower PFAS concentrations. These findings can inform future policies in reducing human exposure to PFAS.
ENVIRONMENTAL RESEARCH
(2023)
Article
Engineering, Environmental
Shelley H. Liu, Leah Feuerstahler, Yitong Chen, Joseph M. Braun, Jessie P. Buckley
Summary: Quantifying a person's cumulative exposure burden to per- and polyfluoroalkyl substances (PFAS) mixtures is important, but different people may be exposed to different sets of PFASs. Using a single measurement model for the entire population may not be appropriate if PFAS exposure sources systematically differ. Therefore, a customized PFAS exposure burden scoring algorithm is developed to ensure equitable comparison across population subgroups. Applying this method to real data, it is found that household income and race/ethnicity influence PFAS burden scores, and using summed PFAS concentrations masks some disparities.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Yun Liu, Richa Gairola, Jordan R. Kuiper, George D. Papandonatos, Karl T. Kelsey, Scott M. Langevin, Jessie P. Buckley, Aimin Chen, Bruce P. Lanphear, Kim M. Cecil, Kimberly Yolton, Joseph M. Braun
Summary: Per- and polyfluoroalkyl substance (PFAS) exposure has been linked to DNA methylation changes in neonates and adults. We previously reported that prenatal PFAS exposure may have a durable impact on DNA methylation from birth to adolescence. However, few studies have examined the association of postnatal PFAS exposure with alterations in DNA methylation.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Lydia M. Louis, Jessie P. Buckley, Jordan R. Kuiper, John D. Meeker, Nadia N. Hansel, Meredith C. McCormack, Gregory Diette, Lesliam Quiros-Alcala
Summary: This study found associations between urinary biomarkers of organophosphate esters (OPEs) and respiratory symptoms in children with asthma. Specifically, higher concentrations of di-n-butyl phosphate (DBuP) were associated with the use of rescue medication.
Article
Public, Environmental & Occupational Health
Tyler J. S. Smith, Alexander P. Keil, Jessie P. Buckley
Summary: This review discusses how epidemiologic studies have used observational data to estimate the effects of potential interventions on early-life environmental exposures. The findings suggest a growing interest in estimating intervention effects on early-life environmental exposures, as they are directly related to possible public health actions. Future studies can link research questions to specific hypothetical interventions to build on existing work.
CURRENT ENVIRONMENTAL HEALTH REPORTS
(2023)