Dynamic landscape of alternative polyadenylation during retinal development

Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization

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A survey of human brain transcriptome diversity at the single cell level

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Alternative mRNA transcription, processing, and translation: insights from RNA sequencing

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A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture

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MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

(2015) Marianne Goodwin et al.   Cell Reports

NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation

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Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease

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Poly(A)-tail profiling reveals an embryonic switch in translational control

(2014) Alexander O. Subtelny et al.   NATURE

Intrinsically different retinal progenitor cells produce specific types of progeny

(2014) Connie Cepko   NATURE REVIEWS NEUROSCIENCE

Implications of polyadenylation in health and disease

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Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease

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Genome-wide identification and predictive modeling of tissue-specific alternative polyadenylation

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Distinct polyadenylation landscapes of diverse human tissues revealed by a modified PA-seq strategy

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Alternative splicing and retinal degeneration

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Widespread and extensive lengthening of 3' UTRs in the mammalian brain

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A compendium of RNA-binding motifs for decoding gene regulation

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Alternative cleavage and polyadenylation: extent, regulation and function

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Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

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miRBase: annotating high confidence microRNAs using deep sequencing data

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Translational control by 3'-UTR-binding proteins

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Intrinsic control of mammalian retinogenesis

(2012) Mengqing Xiang   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamic landscape of tandem 3' UTRs during zebrafish development

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Extensive alternative polyadenylation during zebrafish development

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Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing

(2012) Mainul Hoque et al.   NATURE METHODS

The Neuronal Organization of the Retina

(2012) Richard H. Masland   NEURON

Global Patterns of Tissue-Specific Alternative Polyadenylation in Drosophila

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Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution

(2011) Igor Ulitsky et al.   CELL

The complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins

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The all-trans retinoic acid (atRA)-regulated gene Calmin (Clmn) regulates cell cycle exit and neurite outgrowth in murine neuroblastoma (Neuro2a) cells

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Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing

(2011) Y. Fu et al.   GENOME RESEARCH

The cell adhesion gene PVRL3 is associated with congenital ocular defects

(2011) Salil A. Lachke et al.   HUMAN GENETICS

Synaptic Glutamate Release Is Modulated by the Na+-Driven Cl-/HCOFormula Exchanger Slc4a8

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Mechanisms and Consequences of Alternative Polyadenylation

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Transcriptional activity regulates alternative cleavage and polyadenylation

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The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity

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Neural-specific elongation of 3' UTRs during Drosophila development

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The long noncoding RNA Vax2os1 controls the cell cycle progression of photoreceptor progenitors in the mouse retina

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Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq

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Regulation of mRNA Translation and Stability by microRNAs

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PKCζ-interacting protein ZIP3 is generated by intronic polyadenylation, and is expressed in the brain and retina of the rat

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Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data

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A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression

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Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome

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Formation, regulation and evolution of Caenorhabditis elegans 3′UTRs

(2010) Calvin H. Jan et al.   NATURE

Nova2 Regulates Neuronal Migration through an RNA Switch in Disabled-1 Signaling

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Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation

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Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls

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Alternative mRNA polyadenylation in eukaryotes: an effective regulator of gene expression

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From Progenitors to Differentiated Cells in the Vertebrate Retina

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TopHat: discovering splice junctions with RNA-Seq

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Fast and accurate short read alignment with Burrows-Wheeler transform

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Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

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Reprogramming of 3′ Untranslated Regions of mRNAs by Alternative Polyadenylation in Generation of Pluripotent Stem Cells from Different Cell Types

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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

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F-Seq: a feature density estimator for high-throughput sequence tags

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3′ end mRNA processing: molecular mechanisms and implications for health and disease

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Messenger RNA regulation: to translate or to degrade

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A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors

(2008) F. Qiu et al.   JOURNAL OF NEUROSCIENCE

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

(2008) Steven W. Flavell et al.   NEURON

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE