Matters of life and death. How neutrophils die or survive along NET release and is “NETosis” = necroptosis?

Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis

(2016) Shrikant R. Mulay et al.   Nature Communications

Neutrophil Extracellular Traps Are Pathogenic in Primary Graft Dysfunction after Lung Transplantation

(2015) David M. Sayah et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pyroptotic cell death defends against intracellular pathogens

(2015) Ine Jorgensen et al.   IMMUNOLOGICAL REVIEWS

A novel image-based quantitative method for the characterization of NETosis

(2015) Wenpu Zhao et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN

(2015) S. V. R. Kumar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

(2014) Marc Röhm et al.   INFECTION AND IMMUNITY

Enhanced Formation and Disordered Regulation of NETs in Myeloperoxidase-ANCA-Associated Microscopic Polyangiitis

(2014) D. Nakazawa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

(2014) Kathleen D. Metzler et al.   Cell Reports

Serum Neutrophil Extracellular Trap Levels Predict Thrombotic Microangiopathy after Allogeneic Stem Cell Transplantation

(2013) Yasuyuki Arai et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

(2013) Jason S. Knight et al.   JOURNAL OF CLINICAL INVESTIGATION

An Extracellular Matrix-Based Mechanism of Rapid Neutrophil Extracellular Trap Formation in Response to Candida albicans

(2013) A. S. Byrd et al.   JOURNAL OF IMMUNOLOGY

Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release

(2013) Indira Neeli et al.   Frontiers in Immunology

α-Enolase of Streptococcus pneumoniae Induces Formation of Neutrophil Extracellular Traps

(2012) Yuka Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

(2012) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Anuclear neutrophils keep hunting

(2012) Andreas Peschel et al.   NATURE MEDICINE

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

(2012) Marc Leshner et al.   Frontiers in Immunology

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

The Development ofN-α-(2-Carboxyl)benzoyl-N5-(2-fluoro-1-iminoethyl)-l-ornithine Amide (o-F-amidine) andN-α-(2-Carboxyl)benzoyl-N5-(2-chloro-1-iminoethyl)-l-ornithine Amide (o-Cl-amidine) As Second Generation Protein Arginine Deiminase (PAD) Inhibitors

(2011) Corey P. Causey et al.   JOURNAL OF MEDICINAL CHEMISTRY

PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection

(2011) Saskia Hemmers et al.   PLoS One

Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3

(2010) Bryan Knuckley et al.   BIOCHEMISTRY

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

(2010) K. D. Metzler et al.   BLOOD

In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days

(2010) J. Pillay et al.   BLOOD

Statins Enhance Formation of Phagocyte Extracellular Traps

(2010) Ohn A. Chow et al.   Cell Host & Microbe

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

Neutrophil kinetics in health and disease

(2010) Charlotte Summers et al.   TRENDS IN IMMUNOLOGY

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

ETosis: A Novel Cell Death Pathway

(2008) F. Wartha et al.   Science Signaling