Selective stimulation of colonic L cells improves metabolic outcomes in mice

Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery

(2019) Pierre Larraufie et al.   Cell Reports

Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

(2019) Charlotte Bayer Christiansen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice

(2019) Youngmi Song et al.   Cell Metabolism

Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake

(2019) Alice E. Adriaenssens et al.   Cell Metabolism

The role of GIP and pancreatic GLP-1 in the glucoregulatory effect of DPP-4 inhibition in mice

(2019) Chelsea R. Hutch et al.   DIABETOLOGIA

Glucagon-like peptide 1 (GLP-1)

(2019) T.D. Müller et al.   Molecular Metabolism

Insulin-like peptide 5 fails to improve metabolism or body weight in obese mice

(2019) Alexander N. Zaykov et al.   PEPTIDES

Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice – Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1 co-expressing cells

(2019) Lawrence J. Billing et al.   Molecular Metabolism

The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

(2018) Charlotte Bayer Christiansen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anorectic response to the trichothecene T-2 toxin correspond to plasma elevations of the satiety hormone glucose-dependent insulinotropic polypeptide and peptide YY 3-36

(2018) Kun Sheng et al.   TOXICOLOGY

Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites

(2018) Mari L. Lund et al.   Molecular Metabolism

Co-storage and release of insulin-like peptide-5, glucagon-like peptide-1 and peptideYY from murine and human colonic enteroendocrine cells

(2018) Lawrence J. Billing et al.   Molecular Metabolism

Insulin Secretion Depends on Intra-islet Glucagon Signaling

(2018) Berit Svendsen et al.   Cell Reports

Single-cell RNA-sequencing reveals a distinct population of proglucagon-expressing cells specific to the mouse upper small intestine

(2017) Leslie L. Glass et al.   Molecular Metabolism

Enteroendocrine Cells: Chemosensors in the Intestinal Epithelium

(2016) Fiona M. Gribble et al.   Annual Review of Physiology

Angiotensin II Type 1 Receptor-Dependent GLP-1 and PYY Secretion in Mice and Humans

(2016) Ramona Pais et al.   ENDOCRINOLOGY

Role of enteroendocrine L-cells in arginine vasopressin-mediated inhibition of colonic anion secretion

(2016) Ramona Pais et al.   JOURNAL OF PHYSIOLOGY-LONDON

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production

(2016) Ying Shiuan Lee et al.   Molecular Metabolism

The insulinotrophic effect of insulin-like peptide 5in vitroandin vivo

(2015) Xiao Luo et al.   BIOCHEMICAL JOURNAL

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

(2015) Cheryl A. Brighton et al.   ENDOCRINOLOGY

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

(2014) Edward S Chambers et al.   GUT

Peptide YY, neuropeptide Y and corticotrophin-releasing factor modulate gastrointestinal motility and food intake during acute stress

(2014) Sarah C. Forbes et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Insulin-like peptide 5 is an orexigenic gastrointestinal hormone

(2014) J. Grosse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Important role of mucosal serotonin in colonic propulsion and peristaltic reflexes:in vitroanalyses in mice lacking tryptophan hydroxylase 1

(2013) Dante J. Heredia et al.   JOURNAL OF PHYSIOLOGY-LONDON

Action and therapeutic potential of oxyntomodulin

(2013) Alessandro Pocai   Molecular Metabolism

Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion

(2012) H. E. Parker et al.   DIABETOLOGIA

Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers

(2012) T. E. Adrian et al.   DIABETOLOGIA

Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y1and Y2receptors

(2011) IR Tough et al.   BRITISH JOURNAL OF PHARMACOLOGY

Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

(2011) V. Gorboulev et al.   DIABETES

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

(2011) Helga Ellingsgaard et al.   NATURE MEDICINE

Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents

(2010) Y-L Liu et al.   INTERNATIONAL JOURNAL OF OBESITY

In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y2 receptor

(2009) James R. Shoblock et al.   PSYCHOPHARMACOLOGY

Glucose Sensing in L Cells: A Primary Cell Study

(2008) Frank Reimann et al.   Cell Metabolism