Journal
Cell Stem Cell
Volume 19, Issue 5, Pages 563-565Publisher
CELL PRESS
DOI: 10.1016/j.stem.2016.10.011
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Funding
- British Heart Foundation [RM/13/2/30158] Funding Source: Medline
- Medical Research Council [G1000816] Funding Source: Medline
- MRC [G1000816] Funding Source: UKRI
- British Heart Foundation [RG/14/3/30706] Funding Source: researchfish
- Medical Research Council [G1000816] Funding Source: researchfish
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Blood vessels significantly remodel in response to injury and pathologic conditions, although the contribution of stem cells to this process is unclear. Now in Cell Stem Cell, Kramann et al. ( 2016) show that Gli1+ perivascular cells in the outermost vessel layer are progenitors that substantially contribute to pathologic vessel remodeling.
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