Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration

Genetic compensation triggered by mutant mRNA degradation

(2019) Mohamed A. El-Brolosy et al.   NATURE

Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

(2019) Samuel L. Wolock et al.   Cell Systems

Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium

(2019) Florian Bonkhofer et al.   Nature Communications

Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium

(2018) Michael Lie-A-Ling et al.   DEVELOPMENT

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

The epicardium as a hub for heart regeneration

(2018) Jingli Cao et al.   Nature Reviews Cardiology

Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart

(2018) Héctor Sánchez-Iranzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ

(2018) Tong Zhou et al.   EBioMedicine

Runx1 promotes satellite cell proliferation during ischemia - Induced muscle regeneration

(2018) Meiyu Bao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Runx1-Stat3 signaling regulates the epithelial stem cells in continuously growing incisors

(2018) Safiye E. Sarper et al.   Scientific Reports

Heart Regeneration in the Mexican Cavefish

(2018) William T. Stockdale et al.   Cell Reports

Annexin A2 and cancer: A systematic review

(2017) Maria Christensen et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration

(2017) Shih-Lei Lai et al.   eLife

Runx1 Deficiency Protects Against Adverse Cardiac Remodeling After Myocardial Infarction

(2017) Charlotte S. McCarroll et al.   CIRCULATION

High-Resolution Magnetic Resonance Imaging of the Regenerating Adult Zebrafish Heart

(2017) Jana Koth et al.   Scientific Reports

Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential

(2016) Bartosz Górnikiewicz et al.   BMC GENOMICS

Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration

(2016) Chi-Chung Wu et al.   DEVELOPMENTAL CELL

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers

(2016) Anuradha Illendula et al.   EBioMedicine

Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration

(2015) Jingli Cao et al.   DEVELOPMENT

A dual epimorphic and compensatory mode of heart regeneration in zebrafish

(2015) Pauline Sallin et al.   DEVELOPMENTAL BIOLOGY

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

(2015) Gabriele D’Uva et al.   NATURE CELL BIOLOGY

Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration

(2015) Kfir Baruch Umansky et al.   PLoS Genetics

Differential reparative phenotypes between zebrafish and medaka after cardiac injury

(2014) Kohei Ito et al.   DEVELOPMENTAL DYNAMICS

Transcription factor Runx1 inhibits proliferation and promotes developmental maturation in a selected population of inner olfactory nerve layer olfactory ensheathing cells

(2014) Manjari Murthy et al.   GENE

High Runx1 Levels Promote a Reversible, More-Differentiated Cell State in Hair-Follicle Stem Cells during Quiescence

(2014) Song Eun Lee et al.   Cell Reports

Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression

(2012) H. Jin et al.   BLOOD

Pan-epicardial lineage tracing reveals that epicardium derived cells give rise to myofibroblasts and perivascular cells during zebrafish heart regeneration

(2012) Juan Manuel González-Rosa et al.   DEVELOPMENTAL BIOLOGY

Functional screening identifies miRNAs inducing cardiac regeneration

(2012) Ana Eulalio et al.   NATURE

Mammalian heart renewal by pre-existing cardiomyocytes

(2012) Samuel E. Senyo et al.   NATURE

Cryoinjury as a myocardial infarction model for the study of cardiac regeneration in the zebrafish

(2012) Juan Manuel González-Rosa et al.   Nature Protocols

The role of the annexin A2 heterotetramer in vascular fibrinolysis

(2011) P. A. Madureira et al.   BLOOD

The zebrafish heart regenerates after cryoinjury-induced myocardial infarction

(2011) Fabian Chablais et al.   BMC DEVELOPMENTAL BIOLOGY

Oncostatin M Is a Major Mediator of Cardiomyocyte Dedifferentiation and Remodeling

(2011) Thomas Kubin et al.   Cell Stem Cell

The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion

(2011) Jinhu Wang et al.   DEVELOPMENT

tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration

(2011) K. Kikuchi et al.   DEVELOPMENT

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

(2011) J. M. Gonzalez-Rosa et al.   DEVELOPMENT

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Development of multilineage adult hematopoiesis in the zebrafish with a runx1 truncation mutation

(2010) R. Sood et al.   BLOOD

Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells

(2010) E. Y. N. Lam et al.   BLOOD

The sinus venosus progenitors separate and diversify from the first and second heart fields early in development

(2010) Mathilda T.M. Mommersteeg et al.   CARDIOVASCULAR RESEARCH

Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes

(2010) Kazu Kikuchi et al.   NATURE

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the zebrafish VDA and PBI

(2009) H. Jin et al.   DEVELOPMENT

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors

(2008) E. Yi Ni Lam et al.   BLOOD

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

(2008) N. C. Chi et al.   GENES & DEVELOPMENT