Up-regulation of microRNA-491-5p suppresses cell proliferation and promotes apoptosis by targetingFOXP4in human osteosarcoma

A Single Nucleotide Polymorphism (rs1056629) in 3'-UTR of MMP-9 is Responsible for a Decreased Risk of Metastatic Osteosarcoma by Compromising its Interaction with microRNA-491-5p

(2016) Xiaodong Tian et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-497 inhibits cell proliferation, migration, and invasion by targeting AMOT in human osteosarcoma cells

(2016) Wendong Ruan et al.   OncoTargets and Therapy

Microrna-199a-5p Functions as a Tumor Suppressor via Suppressing Connective Tissue Growth Factor (CTGF) in Follicular Thyroid Carcinoma

(2016) Dawei Sun et al.   MEDICAL SCIENCE MONITOR

FOXP4 modulates tumor growth and independently associates with miR-138 in non-small cell lung cancer cells

(2015) Tian Yang et al.   TUMOR BIOLOGY

MiR-491 attenuates cancer stem cells-like properties of hepatocellular carcinoma by inhibition of GIT-1/NF-κB-mediated EMT

(2015) Xiaojun Yang et al.   TUMOR BIOLOGY

MiR-335 acts as a potential tumor suppressor miRNA via downregulating ROCK1 expression in hepatocellular carcinoma

(2015) Hui Liu et al.   TUMOR BIOLOGY

Overexpression of miRNA-497 inhibits tumor angiogenesis by targeting VEGFR2

(2015) Yingfeng Tu et al.   Scientific Reports

Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

(2014) X Li et al.   ONCOGENE

MicroRNA 135a Suppresses Lymph Node Metastasis through Down-Regulation of ROCK1 in Early Gastric Cancer

(2014) Ji-Young Shin et al.   PLoS One

Inhibition of TGF-β/SMAD3/NF-κB signaling by microRNA-491 is involved in arsenic trioxide-induced anti-angiogenesis in hepatocellular carcinoma cells

(2014) Fei Jiang et al.   TOXICOLOGY LETTERS

miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation

(2014) C Denoyelle et al.   Cell Death & Disease

miRNA-491-5p and GIT1 Serve as Modulators and Biomarkers for Oral Squamous Cell Carcinoma Invasion and Metastasis

(2013) W.-C. Huang et al.   CANCER RESEARCH

MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition

(2013) Yun Zhou et al.   LIVER INTERNATIONAL

High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth

(2013) Suvi-Katri Leivonen et al.   Molecular Oncology

Four MicroRNAs Promote Prostate Cell Proliferation with Regulation of PTEN and Its Downstream Signals In Vitro

(2013) Ling Tian et al.   PLoS One

Current Therapeutic Strategies and Novel Approaches in Osteosarcoma

(2013) Kosei Ando et al.   Cancers

Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma

(2012) Jun Huang et al.   Autophagy

Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF-κB pathway

(2012) Hiroki Goto et al.   CANCER SCIENCE

MicroRNAs: molecular features and role in cancer

(2012) Elodie Lages   Frontiers in Bioscience-Landmark

The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions

(2012) Z. J. Rutnam et al.   JOURNAL OF CELL SCIENCE

MicroRNA miR-491-5p Targeting both TP53 and Bcl-XL Induces Cell Apoptosis in SW1990 Pancreatic Cancer Cells through Mitochondria Mediated Pathway

(2012) Rong Guo et al.   MOLECULES

Replication and Fine Mapping for Association of the C2orf43, FOXP4, GPRC6A and RFX6 Genes with Prostate Cancer in the Chinese Population

(2012) Qing-Zhi Long et al.   PLoS One

Foxp4 Is Dispensable for T Cell Development, but Required for Robust Recall Responses

(2012) Karla R. Wiehagen et al.   PLoS One

Modulation of the Osteosarcoma Expression Phenotype by MicroRNAs

(2012) Heidi M. Namløs et al.   PLoS One

MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells

(2011) Shipeng Feng et al.   NUCLEIC ACIDS RESEARCH

Osteosarcoma – conventional treatment vs. gene therapy

(2010) Mei Lin Tan et al.   CANCER BIOLOGY & THERAPY

Foxp1/2/4-NuRD Interactions Regulate Gene Expression and Epithelial Injury Response in the Lung via Regulation of Interleukin-6

(2010) Ann L. Chokas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of matrix metalloproteinase regulator, RECK, and its clinical significance in osteosarcoma

(2010) Jianda Xu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-XL in colorectal cancer cells

(2009) Haruo Nakano et al.   INTERNATIONAL JOURNAL OF CANCER

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

(2008) C. R. Walkley et al.   GENES & DEVELOPMENT

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS