The oncolytic compound LTX-401 targets the Golgi apparatus

The oncolytic peptide LTX-315 overcomes resistance of cancers to immunotherapy with CTLA4 checkpoint blockade

(2016) T Yamazaki et al.   CELL DEATH AND DIFFERENTIATION

The Cytolytic Amphipathic β(2,2)-Amino Acid LTX-401 Induces DAMP Release in Melanoma Cells and Causes Complete Regression of B16 Melanoma

(2016) Liv-Marie Eike et al.   PLoS One

The oncolytic peptide LTX-315 triggers immunogenic cell death

(2016) H Zhou et al.   Cell Death & Disease

Novel inducers of BECN1-independent autophagy:cis-unsaturated fatty acids

(2015) Mireia Niso-Santano et al.   Autophagy

The oncolytic peptide LTX-315 triggers necrotic cell death

(2015) Sabrina Forveille et al.   CELL CYCLE

Unsaturated fatty acids induce non-canonical autophagy

(2015) M. Niso-Santano et al.   EMBO JOURNAL

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization

(2015) Heng Zhou et al.   Oncotarget

Complete regression and systemic protective immune responses obtained in B16 melanomas after treatment with LTX-315

(2014) Ketil André Camilio et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Organelle-specific initiation of cell death

(2014) Lorenzo Galluzzi et al.   NATURE CELL BIOLOGY

Molecular mechanisms of regulated necrosis

(2014) Lorenzo Galluzzi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

LTX-315 (Oncopore™)

(2014) Ketil André Camilio et al.   OncoImmunology

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Anticancer mechanisms of action of two small amphipathic β2,2-amino acid derivatives derived from antimicrobial peptides

(2012) Dominik Ausbacher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Human Embryonic Stem Cells Have Constitutively Active Bax at the Golgi and Are Primed to Undergo Rapid Apoptosis

(2012) Raluca Dumitru et al.   MOLECULAR CELL

Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress

(2010) I Martins et al.   ONCOGENE

Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis

(2010) J P X Cheng et al.   Cell Death & Disease

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY