Differential localization of A-Raf regulates MST2-mediated apoptosis during epithelial differentiation

A(nother) RAF mutation in LCH

(2014) K. Shannon et al.   BLOOD

Somatic activating ARAF mutations in Langerhans cell histiocytosis

(2014) D. S. Nelson et al.   BLOOD

Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma

(2014) Marcin Imielinski et al.   JOURNAL OF CLINICAL INVESTIGATION

HGF Induces Epithelial-to-Mesenchymal Transition by Modulating the Mammalian Hippo/MST2 and ISG15 Pathways

(2014) Jennifer Farrell et al.   JOURNAL OF PROTEOME RESEARCH

Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling

(2014) David Romano et al.   NATURE CELL BIOLOGY

Mst1 and Mst2 Are Essential Regulators of Trophoblast Differentiation and Placenta Morphogenesis

(2014) Xingrong Du et al.   PLoS One

Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development

(2014) A. Shilo et al.   RNA

KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

(2013) Laura R. Pearce et al.   CELL

Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

(2013) Tao Gao et al.   GASTROENTEROLOGY

The Hippo pathway: regulators and regulations

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors

(2013) Susumu Nejigane et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Functional Role of Mst1/Mst2 in Embryonic Stem Cell Differentiation

(2013) Peng Li et al.   PLoS One

Crossroads of Wnt and Hippo in epithelial tissues

(2013) Ilenia Bernascone et al.   TRENDS IN CELL BIOLOGY

Kinase Suppressor of Ras 2 (KSR2) Regulates Tumor Cell Transformation via AMPK

(2012) M. R. Fernandez et al.   MOLECULAR AND CELLULAR BIOLOGY

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

(2011) B. Zhao et al.   GENES & DEVELOPMENT

Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis

(2011) Yeqi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterogeneous Nuclear Ribonucleoprotein H Blocks MST2-Mediated Apoptosis in Cancer Cells by Regulating a-raf Transcription

(2010) J. Rauch et al.   CANCER RESEARCH

Angiomotin-like Proteins Associate with and Negatively Regulate YAP1

(2010) Wenqi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

(2010) Cory M. Johannessen et al.   NATURE

Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway

(2009) Lin Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

KSR2 Is an Essential Regulator of AMP Kinase, Energy Expenditure, and Insulin Sensitivity

(2009) Diane L. Costanzo-Garvey et al.   Cell Metabolism

KSR2 Is a Calcineurin Substrate that Promotes ERK Cascade Activation in Response to Calcium Signals

(2009) Michele K. Dougherty et al.   MOLECULAR CELL

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Positive Regulation of A-RAF by Phosphorylation of Isoform-specific Hinge Segment and Identification of Novel Phosphorylation Sites

(2008) Angela Baljuls et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-14 reveals its secrets

(2008) Geertrui Denecker et al.   JOURNAL OF CELL BIOLOGY

Ras Subcellular Localization Defines Extracellular Signal-Regulated Kinase 1 and 2 Substrate Specificity through Distinct Utilization of Scaffold Proteins

(2008) B. Casar et al.   MOLECULAR AND CELLULAR BIOLOGY

Essential Role of ERK Dimers in the Activation of Cytoplasmic but Not Nuclear Substrates by ERK-Scaffold Complexes

(2008) Berta Casar et al.   MOLECULAR CELL

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE