Proline isomerisation as a novel regulatory mechanism for p38MAPK activation and functions

Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape

(2015) David W. Litchfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cyclophilin A as a Target of Cisplatin Chemosensitizers

(2014) Gerhard Hamilton   CURRENT CANCER DRUG TARGETS

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

(2014) Ramona Rudalska et al.   NATURE MEDICINE

Cyclophilin A (CypA) Interacts with NF-κB Subunit, p65/RelA, and Contributes to NF-κB Activation Signaling

(2014) Shan Sun et al.   PLoS One

Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade

(2014) X. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockdown of cyclophilin A reverses paclitaxel resistance in human endometrial cancer cells via suppression of MAPK kinase pathways

(2013) Zhengyu Li et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A

(2013) Aldo Germani et al.   CANCER LETTERS

Cyclophilin B Supports Myc and Mutant p53-Dependent Survival of Glioblastoma Multiforme Cells

(2013) Jae Won Choi et al.   CANCER RESEARCH

Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK

(2013) Lorena Pereira et al.   EMBO Molecular Medicine

A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo

(2013) Sandra Morandell et al.   Cell Reports

Phosphorylated p38 and JNK MAPK proteins in hepatocellular carcinoma

(2012) Shen-Nien Wang et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

A critical step for JNK activation: isomerization by the prolyl isomerase Pin1

(2011) J E Park et al.   CELL DEATH AND DIFFERENTIATION

Prolyl cis/trans isomerase signalling pathways in cancer

(2011) Martin Theuerkorn et al.   CURRENT OPINION IN PHARMACOLOGY

Inhibition of p38 MAPK-Dependent Excision Repair Cross-Complementing 1 Expression Decreases the DNA Repair Capacity to Sensitize Lung Cancer Cells to Etoposide

(2011) M.-S. Tsai et al.   MOLECULAR CANCER THERAPEUTICS

Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC

(2011) Eva M. Galan-Moya et al.   PLoS One

Targeting the p38 MAPK Pathway Inhibits Irinotecan Resistance in Colon Adenocarcinoma

(2010) S. Paillas et al.   CANCER RESEARCH

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

(2010) T. G. Oliver et al.   GENES & DEVELOPMENT

Current implications of cyclophilins in human cancers

(2010) Jinhwa Lee et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB

(2010) Shan Sun et al.   JOURNAL OF NEURO-ONCOLOGY

The cleavage fragment of retinoid X receptor-α ligand binding domain inhibits radiosensitization by retinoic acid

(2010) Han   ONCOLOGY REPORTS

p38MAPK Controls Expression of Multiple Cell Cycle Inhibitors and Islet Proliferation with Advancing Age

(2009) Esther Sook Miin Wong et al.   DEVELOPMENTAL CELL

Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells

(2009) K Bauer et al.   ONCOGENE

Expression of Cyclophilin B is Associated with Malignant Progression and Regulation of Genes Implicated in the Pathogenesis of Breast Cancer

(2008) Feng Fang et al.   AMERICAN JOURNAL OF PATHOLOGY

Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold#

(2008) Brad Herberich et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparative Proteomic Analysis of Matched Primary and Metastatic Melanoma Cell Lines

(2008) Mohammad Al-Ghoul et al.   JOURNAL OF PROTEOME RESEARCH

Proteomics Identification of Cyclophilin A as a Potential Prognostic Factor and Therapeutic Target in Endometrial Carcinoma

(2008) Zhengyu Li et al.   MOLECULAR & CELLULAR PROTEOMICS