Novel functions for the transcription factor E2F4 in development and disease

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause

(2016) Roberta Scognamiglio et al.   CELL

E2f4 and E2f5 are essential for the development of the male reproductive system

(2016) Paul S. Danielian et al.   CELL CYCLE

GEMC1 is a critical regulator of multiciliated cell differentiation

(2016) Berta Terré et al.   EMBO JOURNAL

RB1: a prototype tumor suppressor and an enigma

(2016) Nicholas J. Dyson   GENES & DEVELOPMENT

Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis

(2015) Michael S. Kareta et al.   Cell Stem Cell

Multicilin drives centriole biogenesis via E2f proteins

(2014) L. Ma et al.   GENES & DEVELOPMENT

CpG island-mediated global gene regulatory modes in mouse embryonic stem cells

(2014) Samuel Beck et al.   Nature Communications

ERK-associated changes in E2F4 phosphorylation, localization and transcriptional activity during mitogenic stimulation in human intestinal epithelial crypt cells

(2013) Marie-Christine Paquin et al.   BMC CELL BIOLOGY

Control of cell cycle transcription during G1 and S phases

(2013) Cosetta Bertoli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Opposing Activities of DRM and MES-4 Tune Gene Expression and X-Chromosome Repression in Caenorhabditis elegans Germ Cells

(2013) Tomoko M. Tabuchi et al.   G3-Genes Genomes Genetics

Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs

(2013) Michelle Kudron et al.   GENOME BIOLOGY

p27Kip1 Directly Represses Sox2 during Embryonic Stem Cell Differentiation

(2012) Han Li et al.   Cell Stem Cell

The Retinoblastoma pathway regulates stem cell proliferation in freshwater planarians

(2012) Shu Jun Zhu et al.   DEVELOPMENTAL BIOLOGY

Anti-apoptotic function of the E2F transcription factor 4 (E2F4)/p130, a member of retinoblastoma gene family in cardiac myocytes

(2012) Dharmendra Dingar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nerve Growth Factor-Induced Cell Cycle Reentry in Newborn Neurons Is Triggered by p38MAPK-Dependent E2F4 Phosphorylation

(2012) S. M. Morillo et al.   MOLECULAR AND CELLULAR BIOLOGY

A Dual Role for the dREAM/MMB Complex in the Regulation of Differentiation-Specific E2F/RB Target Genes

(2012) H. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

The RB family is required for the self-renewal and survival of human embryonic stem cells

(2012) Jamie F. Conklin et al.   Nature Communications

Tissue-specific Gene Targeting by the Multiprotein Mammalian DREAM Complex

(2011) Stephen Flowers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis

(2011) Bum-Kyu Lee et al.   NUCLEIC ACIDS RESEARCH

A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

(2010) Jonghwan Kim et al.   CELL

Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130

(2010) D. C. Hegan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E2F4 is required for cardiomyocyte proliferation

(2009) Machteld J. van Amerongen et al.   CARDIOVASCULAR RESEARCH

E2F4 Is Required for Early Eye Patterning

(2009) Vladimir A. Ruzhynsky et al.   DEVELOPMENTAL NEUROSCIENCE

ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4

(2009) Carmen Dominguez-Brauer et al.   EMBO REPORTS

E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells

(2009) Hugo Garneau et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Atypical E2Fs: new players in the E2F transcription factor family

(2009) Tim Lammens et al.   TRENDS IN CELL BIOLOGY