TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription
Authors
Keywords
-
Journal
CELL CYCLE
Volume 15, Issue 20, Pages 2712-2722
Publisher
Informa UK Limited
Online
2016-08-27
DOI
10.1080/15384101.2016.1222337
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Regulation of the imprintedDlk1-Dio3locus by allele-specific enhancer activity
- (2016) Zhuojuan Luo et al. GENES & DEVELOPMENT
- CDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells
- (2015) Elisa Laurenti et al. Cell Stem Cell
- Germline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesin
- (2015) Kosuke Izumi et al. NATURE GENETICS
- DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
- (2015) Chun-Wei Chen et al. NATURE MEDICINE
- Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription
- (2015) Huasong Lu et al. NUCLEIC ACIDS RESEARCH
- AF4 uses the SL1 components of RNAP1 machinery to initiate MLL fusion- and AEP-dependent transcription
- (2015) Hiroshi Okuda et al. Nature Communications
- Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
- (2014) T. Placke et al. BLOOD
- AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation
- (2014) Yuanyuan Li et al. CELL
- MLL fusion-driven activation ofCDK6potentiates proliferation inMLL-rearranged infant ALL
- (2014) Marieke Van der Linden et al. CELL CYCLE
- Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4
- (2014) Jianyou Gu et al. CELL CYCLE
- MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters
- (2014) Hiroshi Okuda et al. NUCLEIC ACIDS RESEARCH
- AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter
- (2014) Ursula Schulze-Gahmen et al. eLife
- Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes
- (2013) Jocelyn O. Eidahl et al. NUCLEIC ACIDS RESEARCH
- MLL Becomes Functional through Intra-Molecular Interaction Not by Proteolytic Processing
- (2013) Akihiko Yokoyama et al. PLoS One
- RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction
- (2013) Adam C. Wilkinson et al. Cell Reports
- Abrogation of MLL–AF10 and CALM–AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l
- (2012) L Chen et al. LEUKEMIA
- The Super Elongation Complex Family of RNA Polymerase II Elongation Factors: Gene Target Specificity and Transcriptional Output
- (2012) Z. Luo et al. MOLECULAR AND CELLULAR BIOLOGY
- Genome-wide structure and organization of eukaryotic pre-initiation complexes
- (2012) Ho Sung Rhee et al. NATURE
- Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding
- (2012) Benjamin I. Leach et al. STRUCTURE
- Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation
- (2011) S. Y. Jo et al. BLOOD
- DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis
- (2011) A. T. Nguyen et al. BLOOD
- MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
- (2011) Kathrin M. Bernt et al. CANCER CELL
- Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors
- (2011) Hidehisa Takahashi et al. CELL
- Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways
- (2011) A. Yokoyama et al. JOURNAL OF CELL SCIENCE
- NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming
- (2011) Alex J. Kuo et al. MOLECULAR CELL
- Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes
- (2011) D. Biswas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin
- (2011) N. He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The AF4{middle dot}MLL fusion protein is capable of inducing ALL in mice without requirement of MLL{middle dot}AF4
- (2010) A. Bursen et al. BLOOD
- A Higher-Order Complex Containing AF4 and ENL Family Proteins with P-TEFb Facilitates Oncogenic and Physiologic MLL-Dependent Transcription
- (2010) Akihiko Yokoyama et al. CANCER CELL
- MLL-AF9-Induced Leukemogenesis Requires Coexpression of the Wild-Type Mll Allele
- (2010) Austin T. Thiel et al. CANCER CELL
- The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures
- (2010) A Benedikt et al. LEUKEMIA
- t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL
- (2010) Ashish R. Kumar et al. LEUKEMIA RESEARCH
- HIV-1 Tat and Host AFF4 Recruit Two Transcription Elongation Factors into a Bifunctional Complex for Coordinated Activation of HIV-1 Transcription
- (2010) Nanhai He et al. MOLECULAR CELL
- AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia
- (2010) Chengqi Lin et al. MOLECULAR CELL
- HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP
- (2010) Bijan Sobhian et al. MOLECULAR CELL
- The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
- (2010) Sohail Malik et al. NATURE REVIEWS GENETICS
- Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia
- (2009) Tomasz Cierpicki et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes
- (2008) Akihiko Yokoyama et al. CANCER CELL
- H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias
- (2008) Andrei V. Krivtsov et al. CANCER CELL
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started