DNA damage responsive miR-33b-3p promoted lung cancer cells survival and cisplatin resistance by targeting p21WAF1/CIP1

Regulators in the DNA damage response

(2016) Yunhua Liu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer

(2016) Catherine R. Sears et al.   DNA REPAIR

MicroRNA-520g Confers Drug Resistance by Regulating p21 Expression in Colorectal Cancer

(2015) Yang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer

(2015) Lin Zheng et al.   Journal of Translational Medicine

Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells

(2015) Wei Qian et al.   Oncotarget

MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G1/S transition and apoptosis by targeting p21WAF1/CIP1

(2014) H Wang et al.   BRITISH JOURNAL OF CANCER

microRNA regulation of lipoprotein metabolism

(2014) Leigh Goedeke et al.   CURRENT OPINION IN LIPIDOLOGY

Impact of microRNAs in Resistance to Chemotherapy and Novel Targeted Agents in Non-Small Cell Lung Cancer

(2014) Christian Rolfo et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

miR-15b/16-2 Regulates Factors That Promote p53 Phosphorylation and Augments the DNA Damage Response following Radiation in the Lung

(2014) Mohammad Rahman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity

(2014) Marijn T.M. van Jaarsveld et al.   Molecular Oncology

Regulation of microRNA function in somatic stem cell proliferation and differentiation

(2014) Archana Shenoy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9

(2013) Zhuo Dong et al.   CANCER LETTERS

Systematic Screen Identifies miRNAs That Target RAD51 and RAD51D to Enhance Chemosensitivity

(2013) J.-W. Huang et al.   MOLECULAR CANCER RESEARCH

The Long Noncoding RNA HOTAIR Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma Cells via downregualtion of p21WAF1/CIP1 Expression

(2013) Zhili Liu et al.   PLoS One

Multiple Regulatory Layers of SREBP1/2 by SIRT6

(2013) Sivan Elhanati et al.   Cell Reports

ATM–Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response

(2013) Nathan T. Martin et al.   PLoS Genetics

MiR-155 inhibits the sensitivity of lung cancer cells to cisplatin via negative regulation of Apaf-1 expression

(2012) Y-S Zang et al.   CANCER GENE THERAPY

Implication of Posttranslational Histone Modifications in Nucleotide Excision Repair

(2012) Shisheng Li   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

The miR-99 family regulates the DNA damage response through its target SNF2H

(2012) A C Mueller et al.   ONCOGENE

MiR-192 inhibits nucleotide excision repair by targeting ERCC3 and ERCC4 in HepG2.2.15 cells

(2011) Qiong-Hui Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549)

(2011) Hai-Bo Bian et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

miRNA response to DNA damage

(2011) Guohui Wan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging-Related Transcriptional Networks

(2011) Tiara L. A. Kawahara et al.   PLoS Genetics

p21WAF1/CIP1 gene transcriptional activation exerts cell growth inhibition and enhances chemosensitivity to cisplatin in lung carcinoma cell

(2010) Junxia Wei et al.   BMC CANCER

Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks

(2010) Michelle L. Heacock et al.   DNA REPAIR

Phosphorylation of Histone H2A.X by DNA-dependent Protein Kinase Is Not Affected by Core Histone Acetylation, but It Alters Nucleosome Stability and Histone H1 Binding

(2010) Andra Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

(2009) Joris Pothof et al.   EMBO JOURNAL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE