PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease

Published 2016 View Full Article

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Title
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease
Authors
Keywords
type V CRISPR-Cas endonuclease, C2c1, structure, binary complex with sgRNA, ternary complex with added DNA, RuvC catalytic pocket, sequence-specific PAM recognition, genome editing tool
Journal
CELL
Volume 167, Issue 7, Pages 1814-1828.e12
Publisher
Elsevier BV
Online
2016-12-16
DOI
10.1016/j.cell.2016.11.053

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