Plasma levels of trimethylamine-N-oxide can be increased with ‘healthy’ and ‘unhealthy’ diets and do not correlate with the extent of atherosclerosis but with plaque instability

Ingestion of resistant starch by mice markedly increases microbiome-derived metabolites

(2019) Yen Chin Koay et al.   FASEB JOURNAL

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk: A Cross-Sectional Study

(2019) Alexander Kurilshikov et al.   CIRCULATION RESEARCH

Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability

(2019) Philipp Diehl et al.   THROMBOSIS AND HAEMOSTASIS

Association between plasma trimethylamine N-oxide and neoatherosclerosis in patients with very late stent thrombosis

(2019) Yu Tan et al.   CANADIAN JOURNAL OF CARDIOLOGY

Impact of Gut Microbiota and Diet on the Development of Atherosclerosis inApoe−/−Mice

(2018) Annika Lindskog Jonsson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R

(2018) Emmanuel Paradis et al.   BIOINFORMATICS

OUP accepted manuscript

(2018)   EUROPEAN HEART JOURNAL

Plasma trimethylamine N-oxide is associated with vulnerable plaque characteristics in CAD patients as assessed by optical coherence tomography

(2018) Xinxin Liu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

CHRONIC, LOW-DOSE TMAO TREATMENT REDUCES DIASTOLIC DYSFUNCTION AND HEART FIBROSIS IN HYPERTENSIVE RATS.

(2018) Tomasz Huc et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dietary metabolism, the gut microbiome, and heart failure

(2018) W. H. Wilson Tang et al.   Nature Reviews Cardiology

Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target

(2018) Manuel Janeiro et al.   Nutrients

25 years of serving the community with ribosomal RNA gene reference databases and tools

(2017) Frank Oliver Glöckner et al.   JOURNAL OF BIOTECHNOLOGY

Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques

(2017) Nay Min Htun et al.   Nature Communications

Coronary Atherosclerotic Vulnerable Plaque: Current Perspectives

(2017) Christodoulos Stefanadis et al.   Journal of the American Heart Association

Coronary Plaque Characterization Assessed by Optical Coherence Tomography and Plasma Trimethylamine-N-oxide Levels in Patients With Coronary Artery Disease

(2016) Qiang Fu et al.   AMERICAN JOURNAL OF CARDIOLOGY

Do theApoe−/−andLdlr−/–Mice Yield the Same Insight on Atherogenesis?Highlights: Table.

(2016) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis

(2016) Karolina Skagen et al.   ATHEROSCLEROSIS

Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk

(2016) Nathalie Bergeron et al.   BRITISH JOURNAL OF NUTRITION

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations

(2016) Christoph A. Thaiss et al.   CELL

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Microbiota‐Dependent Metabolite Trimethylamine N‐Oxide and Coronary Artery Calcium in the Coronary Artery Risk Development in Young Adults Study (CARDIA)

(2016) Katie A. Meyer et al.   Journal of the American Heart Association

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

(2016) Maximilian Kleinert et al.   Molecular Metabolism

Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control

(2015) Daniel M. Mueller et al.   ATHEROSCLEROSIS

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

Targeted plasma metabolome response to variations in dietary glycemic load in a randomized, controlled, crossover feeding trial in healthy adults

(2015) Sally Barton et al.   Food & Function

Dysbiosis of Gut Microbiota With Reduced Trimethylamine‐N‐Oxide Level in Patients With Large‐Artery Atherosclerotic Stroke or Transient Ischemic Attack

(2015) Jia Yin et al.   Journal of the American Heart Association

Interleukin-6 and Asymmetric Dimethylarginine Are Associated with Platelet Activation after Percutaneous Angioplasty with Stent Implantation

(2015) Thomas Gremmel et al.   PLoS One

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

A Novel Mouse Model of Atherosclerotic Plaque Instability for Drug Testing and Mechanistic/Therapeutic Discoveries Using Gene and MicroRNA Expression Profiling

(2013) Yung-Chih Chen et al.   CIRCULATION RESEARCH

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

(2013) Dan Knights et al.   GUT

2-Aminoadipic acid is a biomarker for diabetes risk

(2013) Thomas J. Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data

(2013) Paul J. McMurdie et al.   PLoS One

Diverse effects of oats on cholesterol metabolism in C57BL/6 mice correlate with expression of hepatic bile acid-producing enzymes

(2012) Kristina E. Andersson et al.   EUROPEAN JOURNAL OF NUTRITION

Intraplaque haemorrhages as the trigger of plaque vulnerability

(2011) J.-B. Michel et al.   EUROPEAN HEART JOURNAL

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase

(2011) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet Activation in Essential Hypertension: Implications for Antiplatelet Treatment

(2010) E. Gkaliagkousi et al.   AMERICAN JOURNAL OF HYPERTENSION

Resistant starch as functional ingredient: A review

(2010) E. Fuentes-Zaragoza et al.   FOOD RESEARCH INTERNATIONAL

UniFrac: an effective distance metric for microbial community comparison

(2010) Catherine Lozupone et al.   ISME Journal

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

(2010) A. K. Benson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relationship of baseline plasma ADMA levels to cardiovascular outcomes at 2 years in men with acute coronary syndrome referred for coronary angiography

(2009) Erdal Cavusoglu et al.   CORONARY ARTERY DISEASE

Isolation of bacteria from the ileal mucosa of TNFdeltaARE mice and description of Enterorhabdus mucosicola gen. nov., sp. nov.

(2009) T. Clavel et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Novel variants of the human flavin-containing monooxygenase 3 (FMO3) gene associated with trimethylaminuria

(2009) Meike S. Motika et al.   MOLECULAR GENETICS AND METABOLISM

Impact of Asymmetric Dimethylarginine on Mortality After Acute Myocardial Infarction

(2008) Marianne Zeller et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Association of low-grade inflammation and platelet activation in patients with hypertension with microalbuminuria

(2008) Patrizia Ferroni et al.   CLINICAL SCIENCE

Bacteria and bacterial rRNA genes associated with the development of colitis in IL-10−/− Mice

(2008) Jingxiao Ye et al.   INFLAMMATORY BOWEL DISEASES

The Mechanism of Carbon Dioxide Catalysis in the Hydrogen Peroxide N-Oxidation of Amines

(2008) Bharathi Balagam et al.   INORGANIC CHEMISTRY