HMGB1 mediates lipopolysaccharide-induced inflammation via interacting with GPX4 in colon cancer cells

Stingless bee honey protects against lipopolysaccharide induced-chronic subclinical systemic inflammation and oxidative stress by modulating Nrf2, NF-κB and p38 MAPK

(2019) Yazan Ranneh et al.   Nutrition & Metabolism

Sinomenine regulates CD14/TLR4, JAK2/STAT3 pathway and calcium signal via α7nAChR to inhibit inflammation in LPS-stimulated macrophages

(2019) Rui-Li Zhu et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

NF-κB as the mediator of metformin's effect on ageing and ageing-related diseases

(2019) Gönül Kanigur Sultuybek et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells

(2019) Oriol de Barrios et al.   GUT

Eriodictyol inhibits high glucose‐induced extracellular matrix accumulation, oxidative stress, and inflammation in human glomerular mesangial cells

(2019) Jin Bai et al.   PHYTOTHERAPY RESEARCH

Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4

(2018) Cong Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ruthenium pyridyl thiocyanate complex increased the production of pro-inflammatory TNFα and IL1β cytokines by the LPS stimulated mammalian macrophages in vitro

(2018) Furkan Ayaz   MOLECULAR BIOLOGY REPORTS

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

(2018) Cong Li et al.   Frontiers in Pharmacology

High-mobility group box 1 protein orchestrates responses to tissue damage via inflammation, innate and adaptive immunity, and tissue repair

(2017) Marco E. Bianchi et al.   IMMUNOLOGICAL REVIEWS

Resveratrol treatment reveals a novel role for HMGB1 in regulation of the type 1 interferon response in dengue virus infection

(2017) Nurhafiza Zainal et al.   Scientific Reports

Rhinosinusal Inflammation and High Mobility Group Box 1 Protein: A New Target for Therapy

(2016) Luisa Maria Bellussi et al.   ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery

HMGB1 as biomarker and drug target

(2016) Emilie Venereau et al.   PHARMACOLOGICAL RESEARCH

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases

(2016) Qingjie Chen et al.   Acta Pharmaceutica Sinica B

p38γ MAPK is required for inflammation-associated colon tumorigenesis

(2015) N Yin et al.   ONCOGENE

Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammationviaHMGB1/TLR4 signalingin vitro

(2015) Fu-Cai Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Overexpression of Receptor for Advanced Glycation End Products and High-Mobility Group Box 1 in Human Dental Pulp Inflammation

(2014) Salunya Tancharoen et al.   MEDIATORS OF INFLAMMATION

Novel Role of Resveratrol

(2014) Wei Xu et al.   SHOCK

Cytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking

(2014) Rachael Zoe Murray et al.   Frontiers in Immunology

Macrophage Cytokines: Involvement in Immunity and Infectious Diseases

(2014) Guillermo Arango Duque et al.   Frontiers in Immunology

Combined Deficiency in Glutathione Peroxidase 4 and Vitamin E Causes Multiorgan Thrombus Formation and Early Death in Mice

(2013) Markus Wortmann et al.   CIRCULATION RESEARCH

The alarmin functions of high-mobility group box-1 and IL-33 in the pathogenesis of systemic lupus erythematosus

(2013) Shui-Lian Yu et al.   Expert Review of Clinical Immunology

An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies

(2013) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

High Mobility Group Box 1 Release from Hepatocytes during Ischemia and Reperfusion Injury Is Mediated by Decreased Histone Deacetylase Activity

(2010) John Evankovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism