Long noncoding RNA MALAT1 inhibits the apoptosis and autophagy of hepatocellular carcinoma cell by targeting the microRNA-146a/PI3K/Akt/mTOR axis

Oncogenic long noncoding RNA MALAT1 and HCV-related hepatocellular carcinoma

(2018) Eman A. Toraih et al.   BIOMEDICINE & PHARMACOTHERAPY

Knockdown of LncRNA MALAT1 contributes to the suppression of inflammatory responses by up-regulating miR-146a in LPS-induced acute lung injury

(2018) Lingling Dai et al.   CONNECTIVE TISSUE RESEARCH

MicroRNAs in Smoking-Related Carcinogenesis: Biomarkers, Functions, and Therapy

(2018) Tomomi Fujii et al.   Journal of Clinical Medicine

MicroRNA-146a-5p Enhances Radiosensitivity in Hepatocellular Carcinoma through Replication Protein A3 Induced Activation of the DNA Repair Pathway

(2018) Jing Luo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Long noncoding RNA HULC modulates the phosphorylation of YB-1 through serving as a scaffold of extracellular signal-regulated kinase and YB-1 to enhance hepatocarcinogenesis

(2017) Dan Li et al.   HEPATOLOGY

Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway

(2017) Yu-Tsai Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation

(2017) Ruibing Chen et al.   NUCLEIC ACIDS RESEARCH

Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis

(2017) Chao Li et al.   Oncotarget

Down-regulation of miR-146a-5p and its potential targets in hepatocellular carcinoma validated by a TCGA- and GEO-based study

(2017) Xin Zhang et al.   FEBS Open Bio

Long noncoding RNA CCHE1 indicates a poor prognosis of hepatocellular carcinoma and promotes carcinogenesis via activation of the ERK/MAPK pathway

(2016) Wei Peng et al.   BIOMEDICINE & PHARMACOTHERAPY

Long Noncoding RNA MALAT1 Promotes Hepatocellular Carcinoma Development by SRSF1 Upregulation and mTOR Activation

(2016) Pushkar Malakar et al.   CANCER RESEARCH

Down-Regulation of LncRNA DGCR5 Correlates with Poor Prognosis in Hepatocellular Carcinoma

(2016) Ruyi Huang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Prognostic significance of long non-coding RNA MALAT-1 in various human carcinomas: a meta-analysis

(2016) J. Wang et al.   GENETICS AND MOLECULAR RESEARCH

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

(2016) Akihiro Fujimoto et al.   NATURE GENETICS

HULC cooperates with MALAT1 to aggravate liver cancer stem cells growth through telomere repeat-binding factor 2

(2016) Mengying Wu et al.   Scientific Reports

Correlation of increased MALAT1 expression with pathological features and prognosis in cancer patients: a meta-analysis

(2015) X.S. Shi et al.   GENETICS AND MOLECULAR RESEARCH

Resveratrol-downregulated phosphorylated liver kinase B1 is involved in senescence of acute myeloid leukemia stem cells

(2015) Dan-yue Peng et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

microRNA-146a inhibits cancer metastasis by downregulating VEGF through dual pathways in hepatocellular carcinoma

(2015) Zheng Zhang et al.   Molecular Cancer

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

(2015) Min-Sik Lee et al.   Nature Communications

A MALAT1/HIF-2α feedback loop contributes to arsenite carcinogenesis

(2015) Fei Luo et al.   Oncotarget

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Does bafilomycin A1block the fusion of autophagosomes with lysosomes?

(2014) Daniel J. Klionsky et al.   Autophagy

Premalignant PTEN-deficient thymocytes activate microRNAs miR-146a and miR-146b as a cellular defense against malignant transformation

(2014) M. L. Burger et al.   BLOOD

Mutual inhibition between YAP and SRSF1 maintains long non-coding RNA, Malat1-induced tumourigenesis in liver cancer

(2014) Jiayi Wang et al.   CELLULAR SIGNALLING

The role of TLR4-mediated PTEN/PI3K/AKT/NF-κB signaling pathway in neuroinflammation in hippocampal neurons

(2014) M. Zhao et al.   NEUROSCIENCE

MicroRNAs in cancer: biomarkers, functions and therapy

(2014) Josie Hayes et al.   TRENDS IN MOLECULAR MEDICINE

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

(2014) Shingo Nakahata et al.   Nature Communications

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models

(2014) Amancio Carnero et al.   Frontiers in Oncology

Akt2 Deficiency Protects from Acute Lung Injury via Alternative Macrophage Activation and miR-146a Induction in Mice

(2013) E. Vergadi et al.   JOURNAL OF IMMUNOLOGY

Upregulation of Rac GTPase-Activating Protein 1 Is Significantly Associated with the Early Recurrence of Human Hepatocellular Carcinoma

(2011) Suk Mei Wang et al.   CLINICAL CANCER RESEARCH

Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma

(2011) Qian Zhou et al.   Future Oncology

Targeted Therapies for Hepatocellular Carcinoma

(2011) Augusto Villanueva et al.   GASTROENTEROLOGY

Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth

(2011) Takayuki Kogure et al.   HEPATOLOGY

Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation

(2011) Ming-chun Lai et al.   MEDICAL ONCOLOGY

An overview of hepatocellular carcinoma study by omics-based methods

(2010) Y. Pei et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The mTOR pathway is associated with the poor prognosis of human hepatocellular carcinoma

(2009) Ledu Zhou et al.   MEDICAL ONCOLOGY

Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises

(2008) Timothy A Yap et al.   CURRENT OPINION IN PHARMACOLOGY

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH