Journal
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
Volume 47, Issue 6, Pages 736-746Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/cjn.2020.75
Keywords
Myelomeningocele; Spinal Lipoma; Lipomyelomeningocele; Dermal Sinus Tract; Neuroembryology
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Spinal dysraphism is an umbrella term that encompasses a number of congenital malformations that affect the central nervous system. The etiology of these conditions can be traced back to a specific defect in embryological development, with the more disabling malformations occurring at an earlier gestational age. A thorough understanding of the relevant neuroembryology is imperative for clinicians to select the correct treatment and prevent complications associated with spinal dysraphism. This paper will review the neuroembryology associated with the various forms of spinal dysraphism and provide a clinical-pathological correlation for these congenital malformations.
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