Article
Cardiac & Cardiovascular Systems
Mayooran Shanmuganathan, Ambra Masi, Matthew K. Burrage, Rafail A. Kotronias, Alessandra Borlotti, Roberto Scarsini, Abhirup Banerjee, Dimitrios Terentes-Printzios, Qiang Zhang, Evan Hann, Elizabeth Tunnicliffe, Andrew Lucking, Jeremy Langrish, Rajesh Kharbanda, Giovanni Luigi De Maria, Adrian P. Banning, Robin P. Choudhury, Keith M. Channon, Stefan K. Piechnik, Vanessa M. Ferreira
Summary: The acute responses in both infarcted and noninfarcted myocardium post-STEMI are independent incremental predictors of long-term major adverse cardiac events (MACE). These findings may have implications for treatment and risk stratification in STEMI.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Genetics & Heredity
Dana Dlouha, Milan Blaha, Pavlina Huckova, Vera Lanska, Jaroslav Alois Hubacek, Vladimir Blaha
Summary: Long-term lipoprotein apheresis treatment has an influence on the dynamic changes of circulating miRNAs, which are involved in the pathogenesis of atherosclerosis. The longer the treatment, the more significant the impact of LA on circulating miRNAs, thereby better reflecting the potential cardiovascular risk.
Article
Environmental Sciences
Yutong Zhu, Yuanyuan Fan, Yuan Xu, Hongbing Xu, Cencen Wu, Tong Wang, Menglin Zhao, Lingyan Liu, Jiageng Cai, Ningman Yuan, Xinpeng Guan, Xinghou He, Jiakun Fang, Qian Zhao, Xiaoming Song, Lingyun Zu, Wei Huang
Summary: This study aimed to assess the acute effects of traffic-related air pollution on ST-segment elevation myocardial infarction, and found that exposure to traffic pollutants was significantly associated with increased risks of STEMI, along with elevations in cardiac impairment markers and reductions in left ventricular ejection fraction. Additionally, the associations were attenuated in participants living in areas with higher residential greenness levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Urology & Nephrology
Davide Bolignano, Marta Greco, Pierangela Presta, Anila Duni, Caterina Vita, Ethymios Pappas, Maria Mirabelli, Lampros Lakkas, Katerina K. Naka, Antonio Brunetti, Daniela Patrizia Foti, Michele Andreucci, Giuseppe Coppolino, Evangelia Dounousi
Summary: Chronic HD patients with severe cardiac alterations have a higher risk of death and adverse CV outcomes. Imbalanced expression of certain miRNAs is related to pathological cardiac remodeling and worse CV outcomes. In this study, circulating levels of miRNA 30a-5p, 23a-3p, and 451a were found to be lower in HD patients and correlated with the severity of cardiac dysfunction. These miRNAs may serve as predictors of worse clinical outcomes.
CLINICAL KIDNEY JOURNAL
(2023)
Review
Endocrinology & Metabolism
Emily A. Rosenberg, Ellen W. Seely
Summary: Cardiovascular disease is the leading cause of death for women, and adverse pregnancy outcomes such as gestational diabetes and preeclampsia are unique risk factors. However, these risk factors are often overlooked by providers. This mini-review focuses on the relationship between gestational diabetes, preeclampsia, and cardiovascular disease, as well as the mechanisms and management strategies for women with a history of adverse pregnancy outcomes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Multidisciplinary Sciences
Mayumi Tsuji, Hiroki Fukahori, Daisuke Sugiyama, Ardith Doorenbos, Katsumi Nasu, Yuriko Mashida, Hirofumi Ogawara
Summary: Globally, residents of long-term care facilities (LTCFs) often experience adverse events (AEs) that result in lawsuits and suffering. A study was conducted in Japan to identify factors associated with liability for damages for AEs in LTCFs. Findings showed that factors such as increased care needs, types of injuries, AE time, organizational factors, and social factors were predictors of liability. Strengthening organizational factors is crucial to prevent AEs and liability for damages.
Article
Medicine, General & Internal
Doo-Hwan Kim, Young-Kug Kim, Tae-Yong Ha, Shin Hwang, Wooil Kim, Hyun-Jung Koo, Dong-Hyun Yang, Joon-Won Kang, Sung-Gyu Lee
Summary: The study evaluated the association between CTCA and long-term MACEs within 5 years after living donor liver transplantation (LDLT), finding that a combination of a coronary artery calcium score (CACS) of >400 and obstructive coronary artery disease (CAD) may be associated with long-term MACEs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Urology & Nephrology
Maelis Kauffmann, Mickael Bobot, Thomas Robert, Stephane Burtey, Gregoire Couvrat-Desvergnes, Frederic Lavainne, Xavier Puechal, Benjamin Terrier, Thomas Quemeneur, Stanislas Faguer, Alexandre Karras, Philippe Brunet, Cecile Couchoud, Noemie Jourde-Chiche
Summary: In patients with ANCA-associated vasculitis, the proportion of patients in remission without immunosuppression increases over time spent on dialysis. During dialysis, patients were far less likely to experience a relapse from their vasculitis than to have serious infections or cardiovascular events.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Shaima H. Algaidi, Doaa I. Alghamdi, Shimaa G. Algheffari, Renad A. Alzahrani, Abrar K. Thabit, Awatif M. Hafiz
Summary: There is a correlation between the use of fluoroquinolones and cardiovascular events, and the development of different cardiovascular events after treatment completion may be influenced by factors such as the specific fluoroquinolone used and the patient's baseline characteristics. Monitoring after treatment is crucial in preventing serious cardiovascular events.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
(2023)
Article
Critical Care Medicine
Raul Mendez, Laura Feced, Victoria Alcaraz-Serrano, Paula Gonzalez-Jimenez, Leyre Bouzas, Ricardo Alonso, Luis Martinez-Dolz, David Hervas, Laia Fernandez-Barat, Antoni Torres, Rosario Menendez
Summary: Cardiovascular events (CVE) during and after exacerbations of bronchiectasis are associated with age, arterial hypertension, chronic obstructive pulmonary disease (COPD), and severe exacerbations. The occurrence of CVE worsens long-term prognosis.
Review
Pathology
Zachary Garrison, Noah Hornick, Jeffrey Cheng, Rajan P. Kulkarni
Summary: Predicting response and side effects of immune checkpoint blockade immunotherapies is crucial for precision oncology. This review discusses recent advances in circulating biomarkers and provides recommendations for their translation into clinical utility.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
(2022)
Article
Multidisciplinary Sciences
Lingyun Gu, Wenlong Jiang, Huidong Qian, Ruolong Zheng, Weizhang Li
Summary: The study demonstrates that elevated FGF21 levels on admission are a powerful predictor of MACEs for STEMI patients after emergency PCI. These levels are correlated with NT-proBNP and hold significant value in predicting the risk of MACEs.
Article
Immunology
Karoline Horisberger, Carmen Portenkirchner, Andreas Rickenbacher, Luc Biedermann, Christoph Gubler, Matthias Turina
Summary: Although immune checkpoint inhibitors have transformed cancer treatment, they can lead to severe side effects that may persist even after treatment discontinuation. Recurrence of severe inflammation after treatment cessation is rare.
Article
Oncology
Charline Lafayolle de la Bruyere, Pierre-Jean Souquet, Stephane Dalle, Pauline Corbaux, Amelie Boespflug, Michael Duruisseaux, Lize Kiakouama-Maleka, Thibaut Reverdy, Madeleine Maugeais, Gulsum Sahin, Denis Maillet, Julien Peron
Summary: Immunotherapy for solid tumors has changed clinical practices, but the impact of adverse events and corticoid use on long-term outcomes remains unclear. A study with 828 patients found no association between adverse events and survival, but corticoid use was linked to shorter time before disease progression. Interruption of immunotherapy correlated with shorter time to progression and survival. Careful management of corticoids and prompt resumption of immunotherapy after adverse events may be crucial for long-term prognosis.
Article
Pediatrics
Prabhjot K. Bedi, Kristie Dehaan, Daniel Ofosu, Deborah Olmstead, Joanna E. Maclean, Maria Castro-Codesal
Summary: This study examined the impact of demographic, clinical, and technology-related factors on long-term NIV adverse events in children. The results showed that NIV-related complications were frequent and were influenced by factors such as age, underlying conditions, and obesity. Appropriate mask-fitting and headgear adaptation, as well as early detection and management of problems, may help to reduce adverse events.
PEDIATRIC PULMONOLOGY
(2023)