Article
Nutrition & Dietetics
Thomas M. S. Wolever, Maike Rahn, ElHadji Dioum, Susan E. Spruill, Adish Ezatagha, Janice E. Campbell, Alexandra L. Jenkins, YiFang Chu
Summary: Consuming a beverage containing 1 g high-MW OBG 3 times daily for 4 weeks significantly reduces LDL cholesterol and cardiovascular disease risk in healthy adults with LDL cholesterol levels between 3 and 5 mmol/L.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Kumpei Tanisawa, Tomoko Ito, Ryoko Kawakami, Chiyoko Usui, Takuji Kawamura, Katsuhiko Suzuki, Shizuo Sakamoto, Kaori Ishii, Isao Muraoka, Koichiro Oka, Mitsuru Higuchi
Summary: The study indicated an association between a dietary pattern characterized by high alcohol intake and lower LDL-cholesterol levels, especially in women. In men, the alcohol dietary pattern may be positively associated with high TAG levels.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Oncology
Pik-Fang Kho, Frederic Amant, Daniela Annibali, Katie Ashton, John Attia, Paul L. Auer, Matthias W. Beckmann, Amanda Black, Louise Brinton, Daniel D. Buchanan, Stephen J. Chanock, Chu Chen, Maxine M. Chen, Timothy H. T. Cheng, Linda S. Cook, Marta Crous-Bous, Kamila Czene, Immaculata De Vivo, Joe Dennis, Thilo Doerk, Sean C. Dowdy, Alison M. Dunning, Matthias Duerst, Douglas F. Easton, Arif B. Ekici, Peter A. Fasching, Brooke L. Fridley, Christine M. Friedenreich, Montserrat Garcia-Closas, Mia M. Gaudet, Graham G. Giles, Ellen L. Goode, Maggie Gorman, Christopher A. Haiman, Per Hall, Susan E. Hankinson, Alexander Hein, Peter Hillemanns, Shirley Hodgson, Erling A. Hoivik, Elizabeth G. Holliday, David J. Hunter, Angela Jones, Peter Kraft, Camilla Krakstad, Diether Lambrechts, Loic Le Marchand, Xiaolin Liang, Annika Lindblom, Jolanta Lissowska, Jirong Long, Lingeng Lu, Anthony M. Magliocco, Lynn Martin, Mark McEvoy, Roger L. Milne, Miriam Mints, Rami Nassir, Geoffrey Otton, Claire Palles, Loreall Pooler, Tony Proietto, Timothy R. Rebbeck, Stefan P. Renner, Harvey A. Risch, Matthias Ruebner, Ingo Runnebaum, Carlotta Sacerdote, Gloria E. Sarto, Fredrick Schumacher, Rodney J. Scott, V. Wendy Setiawan, Mitul Shah, Xin Sheng, Xiao-Ou Shu, Melissa C. Southey, Emma Tham, Ian Tomlinson, Jone Trovik, Constance Turman, Jonathan P. Tyrer, David van den Berg, Zhaoming Wang, Nicolas Wentzensen, Lucy Xia, Yong-Bing Xiang, Hannah P. Yang, Herbert Yu, Wei Zheng, Penelope M. Webb, Deborah J. Thompson, Amanda B. Spurdle, Dylan M. Glubb, Tracy A. O'Mara
Summary: This study used Mendelian randomization analysis to investigate the relationship between blood lipids and endometrial cancer risk. Genetically elevated LDL cholesterol levels were associated with reduced risk of endometrial cancer, while higher predicted HDL cholesterol levels were linked to increased risk of non-endometrioid endometrial cancer. Obesity may influence these associations, but triglycerides showed no evidence of involvement in endometrial cancer development.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Review
Chemistry, Medicinal
Le Wang, Li Feng, Kousalya Prabahar, Benjamin Hernandez-Wolters, Zhenxing Wang
Summary: This umbrella review of intervention meta-analyses confirms the significant reduction of LDL-C, TC, and TG with phytosterol administration. Higher doses (≥2g/day) and longer treatment duration (>8 weeks) have a stronger effect. Phytosterol supplementation may be a complementary therapy for reducing cardiovascular risk.
PHYTOTHERAPY RESEARCH
(2023)
Article
Hematology
Zhiqiang Li, Mulin He, Guangzhi Chen, Tade Souaiaia, Tilla S. Worgall, Xian-Cheng Jiang
Summary: This study found that deficiency in whole-body SM biosynthesis has a significant impact on lipoprotein metabolism, leading to increased levels of cholesterol in the blood and a decrease in LDL receptors. Inhibiting SMS2 synthesis may be a beneficial approach to reduce the risk of cardiovascular diseases.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Malin Schoeneck, David Iggman
Summary: Systematic evaluation found that several foods can effectively reduce LDL cholesterol levels, such as those high in unsaturated and low in saturated and trans fatty acids, those with added plant sterols/stanols, and those high in soluble fiber. Additionally, unfiltered coffee may lead to an increase in cholesterol levels.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Nutrition & Dietetics
Katarina M. Doma, Karen F. Dolinar, D. Dan Ramdath, Thomas M. S. Wolever, Alison M. Duncan
Summary: The study found that daily consumption of 180g of canned beans of multiple varieties can reduce total cholesterol and LDL cholesterol, providing a practical strategy for reducing the risk of cardiovascular diseases.
JOURNAL OF NUTRITION
(2021)
Article
Veterinary Sciences
Chayanne Silva Ferreira, Thiago Henrique Annibale Vendramini, Andressa Rodrigues Amaral, Mariana Fragoso Rentas, Mariane Ceschin Ernandes, Flavio Lopes da Silva, Patricia Massae Oba, Fernando de Oliveira Roberti Filho, Marcio Antonio Brunetto
Summary: This study found that a diet supplemented with 0.1% beta-glucan can lower blood glucose and lipid levels, reduce inflammatory cytokines, and increase satiety parameters in obese dogs. These results provide new possibilities for using beta-glucan in the prevention and treatment of obesity.
BMC VETERINARY RESEARCH
(2022)
Article
Nutrition & Dietetics
Sarah M. Jung, Ella H. Haddad, Amandeep Kaur, Rawiwan Sirirat, Alice Y. Kim, Keiji Oda, Sujatha Rajaram, Joan Sabate
Summary: This study found that the consumption of fermented soy powder led to significant reductions in total cholesterol and LDL cholesterol, suggesting it may serve as a dietary strategy to manage blood lipids in adults with cardiovascular risk factors.
Review
Biochemistry & Molecular Biology
Saeed Aslani, Bahman Razi, Danyal Imani, Keyhan Mohammadi, Tannaz Jamialahmadi, Zeljko Reiner, Amirhossein Sahebkar
Summary: A systematic review and meta-analysis showed that statin therapy effectively lowered levels of total cholesterol, LDL-C, and TG, and increased levels of HDL-C in patients with different CVDs.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Nutrition & Dietetics
Yixue Yang, Shoumeng Yan, Nan Yao, Yinpei Guo, Han Wang, Mengzi Sun, Wenyu Hu, Xiaotong Li, Ling Wang, Bo Li
Summary: This meta-analysis examined the impact of vitamin D supplementation on blood lipid levels in prediabetic individuals. The results showed that vitamin D intervention significantly reduced triglyceride levels, especially among obese individuals, males, and studies with intervention durations longer than 1 year. Both low and high doses of vitamin D supplementation were effective in reducing triglyceride levels, and this effect was observed in both Northern Europe and Asian countries. However, no significant effects were found on total cholesterol, HDL cholesterol, and LDL cholesterol levels.
FRONTIERS IN NUTRITION
(2023)
Review
Cardiac & Cardiovascular Systems
Vignesh Chidambaram, Harinivaas Shanmugavel Geetha, Amudha Kumar, Marie Gilbert Majella, Ranjith Kumar Sivakumar, Dinesh Voruganti, Jawahar L. Mehta, Petros C. Karakousis
Summary: Low lipid levels are associated with disease severity and mortality in COVID-19 patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Guy De Backer
Summary: This editorial discusses the achievement of reaching ESC/EAS LDL-C treatment goals after an acute coronary syndrome using statins and alirocumab.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Anastasia V. Poznyak, Dmitry A. Kashirskikh, Vasily N. Sukhorukov, Vladislav Kalmykov, Andrey V. Omelchenko, Alexander N. Orekhov
Summary: Atherosclerosis is a major cause of serious cardiovascular disorders, and its pathogenesis involves multiple processes. Reverse transport of cholesterol is a mechanism that plays a protective role against atherosclerosis. Disordered cholesterol metabolism can result in dyslipidemia and early atherosclerosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Immunology
Dengfeng Xu, Meiyuan Feng, YiFang Chu, Shaokang Wang, Varsha Shete, Kieran M. Tuohy, Feng Liu, Xirui Zhou, Alison Kamil, Da Pan, Hechun Liu, Xian Yang, Chao Yang, Baoli Zhu, Na Lv, Qian Xiong, Xin Wang, Jianqin Sun, Guiju Sun, Yuexin Yang
Summary: Oats consumption is beneficial for lipid modulation, leading to significant reductions in TC and LDL-C levels. Oats also have a positive impact on gut microbiome, promoting beneficial bacteria and prebiotic effects.
FRONTIERS IN IMMUNOLOGY
(2021)