Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Hee Kim, Vivian Youngjean Park, Hye Jung Shin, Min Jung Kim, Jung Hyun Yoon
Summary: This study found that a higher volume ratio of U1/U2 derived from ultrafast DCE-MRI was independently associated with pathological complete response in triple-negative invasive breast cancer. Other kinetic features were also associated with pathological complete response in hormone receptor-positive cancers.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Han Sol Kang, Jin You Kim, Jin Joo Kim, Suk Kim, Nam Kyung Lee, Ji Won Lee, Hie Bum Suh, Lee Hwangbo, Yohan Son, Robert Grimm
Summary: Quantitative diffusion parameters derived from DKI and DWI are associated with prognostic factors for breast cancer. Moreover, DKI-derived kurtosis can help distinguish between the molecular subtypes of breast cancer.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Oncology
Ariane A. van Loevezijn, Marieke E. M. van der Noordaa, Erik D. van Werkhoven, Claudette E. Loo, Gonneke A. O. Winter-Warnars, Terry Wiersma, Koen K. van de Vijver, Emilie J. Groen, Charlotte F. J. M. Blanken-Peeters, Bas J. G. L. Zonneveld, Gabe S. Sonke, Frederieke H. van Duijnhoven, Marie-Jeanne T. F. D. Vrancken Peeters
Summary: The study found that ultrasound-guided core biopsies are not accurate enough to identify breast pCR in patients with good response on MRI after neoadjuvant systemic therapy. Therefore, breast surgery cannot be safely omitted based solely on the results of core biopsies in these patients.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stefania Montemezzi, Giuseppe Cardano, Silvia Storer, Nicolo Cardobi, Carlo Cavedon, Lucia Camera
Summary: This study demonstrates the feasibility and efficacy of using DWI in MRI-guided breast biopsies for accurate lesion targeting and device positioning. DWI can effectively detect both mass and non-mass lesions with a minimum size of 5 mm.
EUROPEAN RADIOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Jiang Ouyang, Angel Xie, Jun Zhou, Runcong Liu, Liqiang Wang, Haijun Liu, Na Kong, Wei Tao
Summary: Traditional treatments like chemotherapy and surgery often have severe side effects and cause pain. The emergence of nanomedicines and minimally invasive therapies has brought hope to patients with malignant diseases. Minimally invasive nanomedicines combine the advantages of nanomedicines and minimally invasive therapies, effectively targeting pathological cells and minimizing side effects. This review provides a comprehensive overview of the research status and challenges of minimally invasive nanomedicines and their applications in various fields.
CHEMICAL SOCIETY REVIEWS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Siyao Du, Si Gao, Ruimeng Zhao, Hongbo Liu, Yan Wang, Xixun Qi, Shu Li, Jibin Cao, Lina Zhang
Summary: This study aimed to assess early changes in synthetic relaxometry after neoadjuvant chemotherapy (NAC) for breast cancer and establish a model with contrast-free quantitative parameters for early prediction of pathological response. The results showed that early reduction in synthetic relaxometry indicated pathological response to NAC, and a model combining ADC, T1 changes, tumor size, and cancer subtype effectively predicted pathological response after one NAC cycle.
EUROPEAN RADIOLOGY
(2022)
Article
Oncology
Giacomo Montagna, Minna K. Lee, Varadan Sevilimedu, Andrea Barrio, Monica Morrow
Summary: In cN1 patients rendered cN0 with neoadjuvant chemotherapy, when >= 3 sentinel lymph nodes (SLNs) are removed, the clipped node is an SLN in the majority of cases. Failure to retrieve the clipped node should not be an indication for axillary lymph node dissection (ALND).
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rossella Rella, Enida Bu, Paolo Belli, Anna Rita Scrofani, Federica Petta, Alberto Borghetti, Fabio Marazzi, Vincenzo Valentini, Riccardo Manfredi
Summary: This study retrospectively investigated whether background parenchymal enhancement (BPE) of the contralateral breast on magnetic resonance imaging (MRI) is associated with clinical outcomes in patients with unilateral invasive breast cancer receiving neoadjuvant chemotherapy (NAC). The results showed that BPE was not associated with overall survival (OS) or disease-free survival (DFS), suggesting limited prognostic value.
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2022)
Article
Medicine, General & Internal
Lucija Kovacevic, Marko Petrovecki, Lea Korsa, Zlatko Marusic, Ivo Dumic-Cule, Maja Prutki
Summary: This study aimed to evaluate the performance of multiparametric breast magnetic resonance imaging (mpMRI) for predicting response to neoadjuvant chemotherapy (NAC) in patients with luminal B subtype breast cancer. The study showed that breast mpMRI evaluation before and after two cycles of NAC can effectively predict treatment response.
Article
Radiology, Nuclear Medicine & Medical Imaging
Xueheng Liang, Xingyan Yu, Tianhu Gao
Summary: This meta-analysis examines the diagnostic accuracy of machine learning models with MRI in predicting pathological response to neoadjuvant chemotherapy in breast cancer patients. The study finds that ML applied to MRI demonstrates moderate accuracy in predicting treatment response. Furthermore, deep learning algorithms have higher predictive accuracy compared to ML + radiomics.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hai-Qing Liu, Si-Ying Lin, Yi-Dong Song, Si-Yao Mai, Yue-Dong Yang, Kai Chen, Zhuo Wu, Hui-Ying Zhao
Summary: This study developed a machine learning model based on MRI to predict molecular subtype alterations in breast cancer after neoadjuvant therapy. The model showed favorable predictive efficacy in identifying molecular subtype alteration and could be a useful tool in clinical practice.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhifan Li, Jinkui Li, Xingru Lu, Mengmeng Qu, Jinhui Tian, Junqiang Lei
Summary: This study evaluated and compared DWI and DCE-MRI in predicting the pathological response of breast cancer to NAC, finding no significant difference in diagnostic performance between the two modalities. DWI may be a potential substitute for DCE-MRI, but caution is needed due to the heterogeneity of included studies.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Carlos Bilreiro, Luisa Andrade, Rui Mateus Marques, Celso Matos
Summary: The role of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) measurements for assessing response to neoadjuvant therapy (NAT) in pancreatic cancer is still unclear.
EUROPEAN RADIOLOGY
(2023)
Review
Oncology
Byung Kwan Park, Tae-Joong Kim
Summary: Magnetic resonance imaging (MRI) is a helpful tool in determining tumor size and metastasis for cervical cancer patients, aiding gynecologic oncologists in deciding on minimally invasive surgery and early detection of recurrence.
Review
Chemistry, Multidisciplinary
Peipei Yang, Xin Zhi, Yunxue Xu, Linxue Qian, Zhifei Dai
Summary: Pancreatic carcinoma (PCa) is a highly lethal malignant tumor with limited treatment options. Nanoparticles have been introduced as a medium or carrier to focus energy at the tumor site and minimize side effects. The combination of nanomedicine and minimally invasive techniques provides a new opportunity for the treatment of PCa.
Article
Radiology, Nuclear Medicine & Medical Imaging
Boeun Lee, Sae Rom Chung, Young Jun Choi, Tae-Yon Sung, Dong Eun Song, Tae Yong Kim, Jeong Hyun Lee, Jung Hwan Baek
Summary: The purpose of this study was to assess the diagnostic role of fine-needle aspiration cytology (FNAC) and analyze factors associated with false-negative FNAC results in patients with parathyroid incidentaloma. The results showed that FNAC had low sensitivity for diagnosing parathyroid incidentaloma, and measuring washout parathyroid hormone (PTH) can improve diagnostic accuracy. Obtaining two or more FNA samples can reduce the false-negative rate.
Editorial Material
Oncology
Hyunju Park, Jung Heo, Chang-Seok Ki, Jung Hee Shin, Young Lyun Oh, Young Ik Son, Jee Soo Kim, Sun Wook Kim, Jae Hoon Chung, Tae Yong Kim, Tae Hyuk Kim, Jung-Han Kim
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Hyunju Park, Jung Heo, Chang-Seok Ki, Jung Hee Shin, Young Lyun Oh, Young Ik Son, Jee Soo Kim, Sun Wook Kim, Jae Hoon Chung, Tae Yong Kim, Tae Hyuk Kim, Jung-Han Kim
Summary: This study aimed to clarify the selection criteria for completion thyroidectomy using telomerase reverse transcriptase (TERT) promoter mutation. The results showed that 2 cm was a critical threshold diameter for initial distant metastasis, disease recurrence, and cancer-specific death in minimally invasive and encapsulated angioinvasive follicular thyroid carcinoma with mutant TERT. For follicular thyroid carcinoma with wild-type TERT, the critical diameter was 4 cm.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Tae-Han Kim, In-Ho Kim, Seung Joo Kang, Miyoung Choi, Baek-Hui Kim, Bang Wool Eom, Bum Jun Kim, Byung-Hoon Min, Chang In Choi, Cheol Min Shin, Chung Hyun Tae, Chung Sik Gong, Dong Jin Kim, Arthur Eung-Hyuck Cho, Eun Jeong Gong, Geum Jong Song, Hyeon-Su Im, Hye Seong Ahn, Hyun Lim, Hyung-Don Kim, Jae-Joon Kim, Jeong Il Yu, Jeong Won Lee, Ji Yeon Park, Jwa Hoon Kim, Kyoung Doo Song, Minkyu Jung, Mi Ran Jung, Sang-Yong Son, Shin-Hoo Park, Soo Jin Kim, Sung Hak Lee, Tae-Yong Kim, Woo Kyun Bae, Woong Sub Koom, Yeseob Jee, Yoo Min Kim, Yoonjin Kwak, Young Suk Park, Hye Sook Han, Su Youn Nam, Seong-Ho Kong
Summary: This is the fourth gastric cancer guideline published in Korea, revised in 2018 based on evidence-based approach. It is a collaborative work of an interdisciplinary working group and includes 33 updated or proposed key questions, with 40 statements developed based on systematic review. The evidence level and recommendations were categorized according to the Grading of Recommendations, Assessment, Development and Evaluation proposition. The guideline covers screening, diagnosis, staging and follow-up.
JOURNAL OF GASTRIC CANCER
(2023)
Review
Oncology
Jeesun Yoon, Tae-Yong Kim, Do-Youn Oh
Summary: Gastric cancer is the fourth leading cause of cancer-related deaths globally. Immunotherapy has become an important therapeutic strategy in medical oncology, leading to changes in the treatment of gastric cancer. Immune checkpoint inhibitors have shown significant improvements in survival rates for gastric cancer patients. Further research is being conducted on combination therapies and subsequent treatments to enhance the application of immunotherapy in gastric cancer.
JOURNAL OF GASTRIC CANCER
(2023)
Correction
Endocrinology & Metabolism
Won Gu Kim, Won Bae Kim, Gyeongji Woo, Hyejin Kim, Yumi Cho, Tae Yong Kim, Sun Wook Kim, Myung-Hee Shin, Jin Woo Park, Hai-Lin Park, Kyungwon Oh, Jae Hoon Chung
ENDOCRINOLOGY AND METABOLISM
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
So Yeong Jeong, Jung Hwan Baek, Sae Rom Chung, Young Jun Choi, Ki-Wook Chung, Tae Yong Kim, Jeong Hyun Lee
Summary: The study aimed to evaluate the technical feasibility, efficacy, and safety of anterolateral hydrodissection (ALHD) in radiofrequency ablation (RFA) for benign thyroid nodules. ALHD technique was technically feasible and effective in all patients, achieving a mean initial ablation ratio (IAR) of 90.7%. The ALHD technique also had a pain-relieving effect, resulting in only low amounts of lidocaine administration being required during the procedure.
Letter
Oncology
Hyunju Park, Tae Yong Kim, Tae Hyuk Kim, Jung-Han Kim
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Meihua Jin, Chae A. Kim, Dong Jun Bae, Sang-Yeob Kim, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Won Gu Kim, Min Ji Jeon
Summary: This study evaluated changes in the peripheral blood immune cell population in patients with advanced thyroid cancer receiving lenvatinib treatment to confirm the immune-modulatory effect of lenvatinib. After obtaining informed consent from patients, we prospectively collected 20 ml of whole blood at 2-3 months intervals 2-4 times from each patient; peripheral blood mononuclear cells (PBMCs) were separated, and the Maxpar Direct Immune Profiling Assay was performed. A total of 10 patients were enrolled, and 31 blood samples were obtained. The proportion of peripheral natural killer (NK) cells significantly increased during lenvatinib treatment in advanced thyroid cancer patients, confirming the immune-modulatory effect of lenvatinib.
SCIENTIFIC REPORTS
(2023)
Meeting Abstract
Oncology
Ah Rong Nam, Jeesun Yoon, Kyoung-Seok Oh, Jae-Min Kim, Ju-Hee Bang, Yoojin Jeong, Sea Young Choo, Hyo Jung Kim, Su In Lee, Tae-Yong Kim, Do-Youn Oh
Meeting Abstract
Oncology
Kyoung-Seok Oh, Ah-Rong Nam, Ju-Hee Bang, Yoojin Jeong, Sea Young Choo, Hyo Jung Kim, Su In Lee, Jae-Min Kim, Jeesun Yoon, Tae-Yong Kim, Banyoon Cheon, Hyunju Cha, John Kim, Do-Youn Oh
Meeting Abstract
Oncology
Jeongmin Seo, Jiwon Koh, Dae-Won Lee, Han Suk Ryu, Kyung-Hun Lee, Tae-Yong Kim, Seock-Ah Im
Meeting Abstract
Oncology
Jinyong Kim, Kyeonghun Jeong, Hyeji Jun, Kwangsoo Kim, Tae-Yong Kim, Dae-Won Lee, Go-Un Woo, Songyi Park, Hanbaek Yi, Kyung-Hun Lee, Seock-Ah Im
Correction
Oncology
Tae-Han Kim, In-Ho Kim, Seung Joo Kang, Miyoung Choi, Baek-Hui Kim, Bang Wool Eom, Bum Jun Kim, Byung-Hoon Min, Chang In Choi, Cheol Min Shin, Chung Hyun Tae, Chung Sik Gong, Dong Jin Kim, Arthur Eung-Hyuck Cho, Eun Jeong Gong, Geum Jong Song, Hyeon-Su Im, Hye Seong Ahn, Hyun Lim, Hyung-Don Kim, Jae-Joon Kim, Jeong Il Yu, Jeong Won Lee, Ji Yeon Park, Jwa Hoon Kim, Kyoung Doo Song, Minkyu Jung, Mi Ran Jung, Sang-Yong Son, Shin-Hoo Park, Soo Jin Kim, Sung Hak Lee, Tae-Yong Kim, Woo Kyun Bae, Woong Sub Koom, Yeseob Jee, Yoo Min Kim, Yoonjin Kwak, Young Suk Park, Hye Sook Han, Su Youn Nam, Seong-Ho Kong
JOURNAL OF GASTRIC CANCER
(2023)
Article
Endocrinology & Metabolism
Ahreum Jang, Meihua Jin, Chae A. Kim, Min Ji Jeon, Yu-Mi Lee, Tae-Yon Sung, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Won Gu Kim
Summary: The role of measuring serum thyroglobulin (Tg) levels in predicting the recurrence of papillary thyroid carcinoma (PTC) after lobectomy was investigated. It was found that there was no significant difference in serum Tg levels between the recurrence and non-recurrence groups, and the Tg levels did not show an increasing trend in the recurrence group. Regular monitoring of Tg levels provides little benefit in predicting recurrence for PTC patients who underwent lobectomy.