Article
Medicine, General & Internal
Hisanori Ikuma, Tomohiko Hirose, Dai Nakamura, Kazutaka Yamashita, Masataka Ueda, Kazuhiro Sasaki, Keisuke Kawasaki
Summary: This study conducted a cross-sectional survey on DISH patients and found that DISH is most prevalent at the thoracolumbar junction. Age and hyperostosis around the costovertebral joint were identified as related factors.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jacopo Ciaffi, Elena Borlandelli, Gaia Visani, Giancarlo Facchini, Marco Miceli, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli, Francesco Ursini
Summary: The purpose of this study was to provide updated information on the prevalence of DISH in Italy and describe the clinical and radiographic characteristics associated with the disorder. The results showed that the prevalence of DISH was higher in men and was significantly associated with factors such as age, BMI, diabetes, hypertension, and enthesopathies.
Article
Chemistry, Multidisciplinary
Norihiro Nishida, Fei Jiang, Junji Ohgi, Masahiro Fuchida, Rei Kitazumi, Yuto Yamamura, Rui Tome, Yasuaki Imajo, Hidenori Suzuki, Masahiro Funaba, Xian Chen, Takashi Sakai
Summary: Patients with DISH are more prone to stress on vertebrae, and stresses on vertebrae and intervertebral discs differ depending on the morphology of ossification, even with similar loads. Examining ossification geometry may help surgeons determine the elevated position of stress in the thoracolumbar spine of patients with DISH, contributing to an understanding of the pathogenesis of pain.
APPLIED SCIENCES-BASEL
(2021)
Article
Medicine, General & Internal
Ryosuke Hirota, Atsushi Teramoto, Mitsunori Yoshimoto, Hiroyuki Takashima, Naomi Yasuda, Arihiko Tsukamoto, Noriyuki Iesato, Makoto Emori, Kousuke Iba, Nobuyoshi Kawaharada, Toshihiko Yamashita
Summary: This study investigated the association between the incidence and severity of DISH with vascular calcification and the occurrence of cardiovascular events in heart failure patients. The results showed a higher incidence of DISH in the cardiovascular events group, and DISH patients had more calcification of the coronary arteries and aorta. These findings suggest a correlation between DISH and cardiovascular events.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Riku M. Vierunen, Ville V. Haapamaki, Mika P. Koivikko, Frank V. Bensch
Summary: This study retrospectively reviewed MRI findings of 70 patients with spinal ankylosis from DISH, revealing that 49% had spinal epidural hematoma and 4% had spinal subdural hematoma. It was found that spinal epidural hematoma can cause spinal cord impingement and progress to spinal cord injury.
EUROPEAN RADIOLOGY
(2023)
Article
Rheumatology
Geoffrey O. Littlejohn
Summary: Diffuse idiopathic skeletal hyperostosis (DISH) is a common disorder in human history with diverse distribution in ancient populations. Metabolic factors play an important role in ancient populations affected by DISH.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2022)
Article
Rheumatology
Stefanie F. Pini, Emilio Pariente, Jose M. Olmos, Marta Martin-Millan, Raquel Pascua, Victor M. Martinez-Taboada, Jose L. Hernandez
Summary: This study aimed to assess the association between trabecular bone score (TBS) and diffuse idiopathic skeletal hyperostosis (DISH) in postmenopausal women. The results showed a significant association between DISH and TBS, with lower TBS values in DISH patients and a higher prevalence of osteoporosis and vertebral fractures.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2023)
Article
Endocrinology & Metabolism
Xiaojiang Sun, Han Qiao, Xiaofei Cheng, Haijun Tian, Kangping Shen, Wenjie Jin, Xingzhen Liu, Qiang Wang, Yiming Miao, Yue Xu, Changqing Zhao, Jie Zhao
Summary: Andersson lesions in ankylosing spondylitis pose a serious risk to spinal stability, while erosive discovertebral lesions in diffuse idiopathic skeletal hyperostosis share clinical similarities but may not be recognized as unstable lesions. By characterizing discovertebral lesions similar to Andersson-like lesions in DISH, this study highlights the importance of early intervention for maintaining spinal stability.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Health Care Sciences & Services
Massimo Mesolella, Sarah Buono, Roberto D'Aniello, Annarita Ascione, Gaetano Motta, Salvatore Allosso
Summary: Forestier's disease is a systemic, degenerative metabolic condition characterized by the progressive ossification of the ligaments and entheses. This case report presents a 63-year-old man who had a painless mass in the pre-auricular region, gradually worsening dysphonia, severe dysphagia relating to solids, stiffness, and mild pain at the back of the neck. After further diagnostic tests, diffuse spondylarthrosis and beak-like osteophytes at C2-C5 were identified, causing esophageal compression. Intensive logopedic and postural rehabilitative treatment led to significant improvement in dysphagia symptoms, while medical therapy was limited to indomethacin to control osteophytic process.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Health Care Sciences & Services
Netanja Harlianto, Jan Westerink, Wouter Foppen, Marjolein E. Hol, Rianne Wittenberg, Pieternella H. van der Veen, Bram van Ginneken, Jonneke S. Kuperus, Jorrit-Jan Verlaan, Pim A. de Jong, Firdaus A. A. Mohamed Hoesein
Summary: Obesity and type 2 diabetes are associated with the development of DISH, with a strong relation to VAT. The association between VAT and DISH differs slightly between sexes.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Clinical Neurology
Yusuke Murakami, Tadao Morino, Masayuki Hino, Hiroshi Misaki, Hiroshi Imai, Hiromasa Miura
Summary: This study investigated the relationship between ligament ossification and the range of motion (ROM) of the lumbar spine and developed a new scoring system. The results showed that as the score increased, ROM significantly decreased, indicating that the scoring system can reflect lumbar mobility. This scoring system is effective for assessing fractures and spinal conditions, as well as monitoring treatment outcomes and changes over time.
GLOBAL SPINE JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Mikolaj Dabrowski, Lukasz Kubaszewski
Summary: DISH is characterized by calcification and ossification of cervical spine ligaments, potentially leading to dysphagia. It is more common in men with metabolic disorders and is often asymptomatic, with poorly understood etiology.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Clinical Neurology
Maximilian Schwendner, Martin Seule, Bernhard Meyer, Sandro M. Krieg
Summary: This study evaluated patient characteristics and procedures in patients with ankylosing spinal disorders (ASDs), finding that timely preoperative imaging and surgical treatment procedures are crucial for patient outcomes.
NEUROSURGICAL FOCUS
(2021)
Article
Endocrinology & Metabolism
Mitsuru Furukawa, Kunimasa Okuyama, Ken Ninomiya, Yoshiyuki Yato, Takeshi Miyamoto, Masaya Nakamura, Morio Matsumoto
Summary: The study found a correlation between max vertebral bodies and bone mineral density, with bone cross-link thickness only correlating within a specific range. After adjusting, specific max VB groups showed significantly higher femur proximal bone mineral density.
JOURNAL OF BONE AND MINERAL METABOLISM
(2022)
Article
Orthopedics
YuLei Dong, Jiahao Li, Kaili Yang, Shigong Guo, Jiliang Zhai, Yu Zhao
Summary: This study retrospectively analyzed 100 patients with thoracic spondylotic myelopathy who underwent spinal decompression and fusion surgery. The patients were divided into DISH and non-DISH groups. The results showed that DISH occurred more in male patients with larger BMI. The incidence of upper thoracic vertebrae with OPLL and lumbar spine with OLF was higher in the DISH group. There were no significant differences between the two groups in surgical outcomes.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
