Risk assessment for humans using physiologically based pharmacokinetic model of diethyl phthalate and its major metabolite, monoethyl phthalate

Steady-State Human Pharmacokinetics of Monobutyl Phthalate Predicted by Physiologically Based Pharmacokinetic Modeling Using Single-Dose Data from Humanized-Liver Mice Orally Administered with Dibutyl Phthalate

(2019) Tomonori Miura et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Simultaneous determination of diethyl phthalate and its major metabolite, monoethyl phthalate, in rat plasma, urine, and various tissues collected from a toxicokinetic study by ultrahigh performance liquid chromatography-tandem mass spectrometry

(2019) Seung-Hyun Jeong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Excretion of Di-2-ethylhexyl phthalate (DEHP) metabolites in urine is related to body mass index because of higher energy intake in the overweight and obese

(2018) Jerry L. Campbell et al.   ENVIRONMENT INTERNATIONAL

Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: a bottom up modeling approach

(2018) Raju Prasad Sharma et al.   TOXICOLOGY LETTERS

Finding synergies for 3Rs – Toxicokinetics and read-across: Report from an EPAA partners' Forum

(2018) Charles Laroche et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Exploring sex differences in human health risk assessment for PFNA and PFDA using a PBPK model

(2018) Sook-Jin Kim et al.   ARCHIVES OF TOXICOLOGY

A Whole-Body Physiologically Based Pharmacokinetic Model of Gefitinib in Mice and Scale-Up to Humans

(2015) Youwei Bi et al.   AAPS Journal

Human biomonitoring of phthalate exposure in Austrian children and adults and cumulative risk assessment

(2015) Christina Hartmann et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

The Scientific Basis of Uncertainty Factors Used in Setting Occupational Exposure Limits

(2015) D. A. Dankovic et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE

Age and Gender Differences in Urinary Levels of Eleven Phthalate Metabolites in General Taiwanese Population after a DEHP Episode

(2015) Po-Chin Huang et al.   PLoS One

The binding affinity of phthalate plasticizers-protein revealed by spectroscopic techniques and molecular modeling

(2014) Yuanyuan Yue et al.   FOOD AND CHEMICAL TOXICOLOGY

Phthalate metabolites and bisphenol A in urines from German school-aged children: Results of the Duisburg Birth Cohort and Bochum Cohort Studies

(2014) Monika Kasper-Sonnenberg et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Simultaneous determination of imperatorin and its metabolitesin vitroandin vivoby a GC-MS method: application to a bioavailability and protein binding ability study in rat plasma

(2013) Gang Zhao et al.   BIOMEDICAL CHROMATOGRAPHY

Exposure assessment of phthalates in French pregnant women: Results of the ELFE pilot study

(2013) F.A. Zeman et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Urinary excretion of phthalate metabolites, phenols and parabens in rural and urban Danish mother–child pairs

(2013) Hanne Frederiksen et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Children’s Phthalate Intakes and Resultant Cumulative Exposures Estimated from Urine Compared with Estimates from Dust Ingestion, Inhalation and Dermal Absorption in Their Homes and Daycare Centers

(2013) Gabriel Bekö et al.   PLoS One

Phthalate and di-(2-ethylhexyl) adipate (DEHA) intake by German infants based on the results of a duplicate diet study and biomonitoring data (INES 2)

(2012) Hermann Fromme et al.   FOOD AND CHEMICAL TOXICOLOGY

Exposure to Phthalates and Phenols during Pregnancy and Offspring Size at Birth

(2011) Claire Philippat et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: Estimation of daily phthalate intake

(2011) Hanne Frederiksen et al.   ENVIRONMENTAL RESEARCH

Pharmacokinetics, metabolism and excretion of14C-monoethyl phthalate (MEP) and14C-diethyl phthalate (DEP) after single oral and IV administration in the juvenile dog

(2011) Mark L. Kao et al.   XENOBIOTICA

Assessing exposure to phthalates - The human biomonitoring approach

(2010) Matthias Wittassek et al.   MOLECULAR NUTRITION & FOOD RESEARCH

To scale or not to scale: the principles of dose extrapolation

(2009) Vijay Sharma et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reproductive toxicity of phthalate esters

(2009) Anderson Joel Martino-Andrade et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Pharmacokinetics, plasma protein binding and bioavailability of moxifloxacin in Muscovy ducks after different routes of administration

(2009) A. Goudah et al.   RESEARCH IN VETERINARY SCIENCE

Medications as a Potential Source of Exposure to Phthalates in the U.S. Population

(2008) Sonia Hernández-Díaz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Phthalates determination in physiological saline solutions by HPLC–ES-MS

(2008) C FEAS et al.   TALANTA

Tissue Exposures to Free and Glucuronidated Monobutylyphthalate in the Pregnant and Fetal Rat following Exposure to Di-n-butylphthalate: Evaluation with a PBPK Model

(2008) Rebecca A. Clewell et al.   TOXICOLOGICAL SCIENCES

A Mixture of Five Phthalate Esters Inhibits Fetal Testicular Testosterone Production in the Sprague-Dawley Rat in a Cumulative, Dose-Additive Manner

(2008) Kembra L. Howdeshell et al.   TOXICOLOGICAL SCIENCES