Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process

Standardization of Good Manufacturing Practice–compliant production of bone marrow–derived human mesenchymal stromal cells for immunotherapeutic applications

(2015) Patrick Wuchter et al.   CYTOTHERAPY

The translation of cell-based therapies: clinical landscape and manufacturing challenges

(2015) Thomas RJ Heathman et al.   Regenerative Medicine

A potentially scalable method for the harvesting of hMSCs from microcarriers

(2014) Alvin W. Nienow et al.   BIOCHEMICAL ENGINEERING JOURNAL

A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells

(2014) Francisco dos Santos et al.   BIOTECHNOLOGY AND BIOENGINEERING

The Size of Mesenchymal Stem Cells is a Significant Cause of Vascular Obstructions and Stroke

(2014) Jianfeng Ge et al.   Stem Cell Reviews and Reports

Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?

(2014) Guido Moll et al.   STEM CELLS

Eliminating the need of serum testing using low serum culture conditions for human bone marrow-derived mesenchymal stromal cell expansion

(2013) Jessica Wappler et al.   Biomedical Engineering Online

Multiparameter flow cytometry for the characterisation of extracellular markers on human mesenchymal stem cells

(2013) Alexander K. C. Chan et al.   BIOTECHNOLOGY LETTERS

Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor

(2013) Qasim A. Rafiq et al.   BIOTECHNOLOGY LETTERS

Growth, differentiation capacity, and function of mesenchymal stem cells expanded in serum-free medium developed via combinatorial screening

(2013) Kirsten Crapnell et al.   EXPERIMENTAL CELL RESEARCH

Stiffening of human mesenchymal stem cell spheroid microenvironments induced by incorporation of gelatin microparticles

(2012) Priya R. Baraniak et al.   Journal of the Mechanical Behavior of Biomedical Materials

Cultivation in Human Serum Reduces Adipose Tissue-Derived Mesenchymal Stromal Cell Adhesion to Laminin and Endothelium and Reduces Capillary Entrapment

(2012) Lena Dreher et al.   STEM CELLS AND DEVELOPMENT

Population dynamics of mesenchymal stromal cells during culture expansion

(2011) Anne Schellenberg et al.   CYTOTHERAPY

Peak serum: implications of serum supply for cell therapy manufacturing

(2011) David A Brindley et al.   Regenerative Medicine

Developing assays to address identity, potency, purity and safety: cell characterization in cell therapy process development

(2011) Jessica Carmen et al.   Regenerative Medicine

Patterns of Amino Acid Metabolism by Proliferating Human Mesenchymal Stem Cells

(2011) Gustavo A. Higuera et al.   TISSUE ENGINEERING PART A

Toward a Clinical-Grade Expansion of Mesenchymal Stem Cells from Human Sources: A Microcarrier-Based Culture System Under Xeno-Free Conditions

(2011) Francisco dos Santos et al.   TISSUE ENGINEERING PART C-METHODS

Integrins in Cell Migration

(2011) A. Huttenlocher et al.   Cold Spring Harbor Perspectives in Biology

Cryopreservation of human bone marrow-derived mesenchymal stem cells with reduced dimethylsulfoxide and well-defined freezing solutions

(2010) Yang Liu et al.   BIOTECHNOLOGY PROGRESS

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

(2009) Joshua M. Hare et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Growth, Metabolism, and Growth Inhibitors of Mesenchymal Stem Cells

(2009) Deborah Schop et al.   TISSUE ENGINEERING PART A

Effect of holding time, temperature and different parenteral solutions on viability and functionality of adult bone marrow-derived mesenchymal stem cells before transplantation

(2008) Rakhi Pal et al.   Journal of Tissue Engineering and Regenerative Medicine