Optimization and automation of an end-to-end high throughput microscale transient protein production process

Critical agitation for microcarrier suspension in orbital shaken bioreactors: Experimental study and dimensional analysis

(2015) Eric Olmos et al.   CHEMICAL ENGINEERING SCIENCE

Development of a semi-automated high throughput transient transfection system

(2014) Aaron B. Bos et al.   JOURNAL OF BIOTECHNOLOGY

Cross-section perimeter is a suitable parameter to describe the effects of different baffle geometries in shaken microtiter plates

(2014) Clemens Lattermann et al.   Journal of Biological Engineering

Initial evaluation of protein A modified capillary-channeled polymer fibers for the capture and recovery of immunoglobulin G

(2013) Abby J. Schadock-Hewitt et al.   JOURNAL OF SEPARATION SCIENCE

A high-throughput media design approach for high performance mammalian fed-batch cultures

(2013) Yolande Rouiller et al.   mAbs

A simple, robust and highly efficient transient expression system for producing antibodies

(2013) Tom Vink et al.   METHODS

Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies

(2013) Christoph Spiess et al.   NATURE BIOTECHNOLOGY

Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells

(2013) David L. Hacker et al.   PROTEIN EXPRESSION AND PURIFICATION

An automated microscale platform for evaluation and optimization of oxidative bioconversion processes

(2011) Jasmin Z. Baboo et al.   BIOTECHNOLOGY PROGRESS

Manufacturing recombinant proteins in kg-ton quantities using animal cells in bioreactors

(2011) Maria De Jesus et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Automation of large scale transient protein expression in mammalian cells

(2011) Yuguang Zhao et al.   JOURNAL OF STRUCTURAL BIOLOGY

Recent advances in the production of proteins in insect and mammalian cells for structural biology

(2010) Joanne E. Nettleship et al.   JOURNAL OF STRUCTURAL BIOLOGY

The baffled microtiter plate: Increased oxygen transfer and improved online monitoring in small scale fermentations

(2009) Matthias Funke et al.   BIOTECHNOLOGY AND BIOENGINEERING

A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells

(2009) Rachel Legmann et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microwell engineering characterization for mammalian cell culture process development

(2009) Timothy A. Barrett et al.   BIOTECHNOLOGY AND BIOENGINEERING

Fed-batch operation of an industrial cell culture process in shaken microwells

(2009) N. J. Silk et al.   BIOTECHNOLOGY LETTERS

Optimal and consistent protein glycosylation in mammalian cell culture

(2009) P. Hossler et al.   GLYCOBIOLOGY

The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticals

(2009) Tsutomu Arakawa et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Engineering characterisation of a single well from 24-well and 96-well microtitre plates

(2008) Hu Zhang et al.   BIOCHEMICAL ENGINEERING JOURNAL

Comparison of LC and LC/MS methods for quantifying N-glycosylation in recombinant IgGs

(2008) Sandipan Sinha et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY