Ataxia telangiectasia mutated in cardiac fibroblasts regulates doxorubicin-induced cardiotoxicity

Contributions of cardiomyocyte–cardiac fibroblast–immune cell interactions in heart failure development

(2013) Katsuhito Fujiu et al.   BASIC RESEARCH IN CARDIOLOGY

ATM-dependent spontaneous regression of early E -myc-induced murine B-cell leukemia depends on natural killer and T cells

(2013) J. L. Croxford et al.   BLOOD

Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21Cip1

(2013) Zhaokang Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Preclinical Evaluation of a Novel ATM Inhibitor, KU59403, In Vitro and In Vivo in p53 Functional and Dysfunctional Models of Human Cancer

(2013) M. A. Batey et al.   MOLECULAR CANCER THERAPEUTICS

Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways

(2012) Jian Ma et al.   CARDIOVASCULAR RESEARCH

ATR maintains select progenitors during nervous system development

(2012) Youngsoo Lee et al.   EMBO JOURNAL

Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription

(2012) Hilal S Khalil et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

BRCA2 Protein Deficiency Exaggerates Doxorubicin-induced Cardiomyocyte Apoptosis and Cardiac Failure

(2011) Krishna K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiomyocyte Specific Ablation of p53 Is Not Sufficient to Block Doxorubicin Induced Cardiac Fibrosis and Associated Cytoskeletal Changes

(2011) Tiam Feridooni et al.   PLoS One

Ataxia Telangiectasia Mutated (ATM)-mediated DNA Damage Response in Oxidative Stress-induced Vascular Endothelial Cell Senescence

(2010) Hong Zhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Anthracycline Cardiac Injury: Can We Identify Strategies for Cardioprotection?

(2010) Douglas B. Sawyer et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

(2009) Norifumi Takeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Survivin Determines Cardiac Function by Controlling Total Cardiomyocyte Number

(2008) Bodo Levkau et al.   CIRCULATION