Runx2 deletion in smooth muscle cells inhibits vascular osteochondrogenesis and calcification but not atherosclerotic lesion formation

Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice

(2015) Mu-En Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Cholesterol Loading Reprograms the MicroRNA-143/145–Myocardin Axis to Convert Aortic Smooth Muscle Cells to a Dysfunctional Macrophage-Like PhenotypeSignificance

(2015) Yuliya Vengrenyuk et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

(2014) Sima Allahverdian et al.   CIRCULATION

Small entities with large impact

(2014) Joshua D. Hutcheson et al.   CURRENT OPINION IN LIPIDOLOGY

Runx2 Regulates Endochondral Ossification Through Control of Chondrocyte Proliferation and Differentiation

(2014) Haiyan Chen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Loss of Runx2 in Committed Osteoblasts Impairs Postnatal Skeletogenesis

(2014) Mitra D Adhami et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Macrophage-Derived Matrix Vesicles

(2013) Sophie E. P. New et al.   CIRCULATION RESEARCH

Diabetes mellitus accelerates cartilaginous metaplasia and calcification in atherosclerotic vessels of LDLr mutant mice

(2012) Ngoc Nguyen et al.   CARDIOVASCULAR PATHOLOGY

Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study

(2012) Veena Naik et al.   CARDIOVASCULAR RESEARCH

Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification

(2012) Yong Sun et al.   CIRCULATION RESEARCH

Sox9 Directs Hypertrophic Maturation and Blocks Osteoblast Differentiation of Growth Plate Chondrocytes

(2012) Peter Dy et al.   DEVELOPMENTAL CELL

RUNX3 Regulates Intercellular Adhesion Molecule 3 (ICAM-3) Expression during Macrophage Differentiation and Monocyte Extravasation

(2012) Ana Estecha et al.   PLoS One

Elastin Degradation and Vascular Smooth Muscle Cell Phenotype Change Precede Cell Loss and Arterial Medial Calcification in a Uremic Mouse Model of Chronic Kidney Disease

(2011) Ashwini Pai et al.   AMERICAN JOURNAL OF PATHOLOGY

S100A9 Differentially Modifies Phenotypic States of Neutrophils, Macrophages, and Dendritic Cells

(2011) Michelle M. Averill et al.   CIRCULATION

Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesis

(2010) Mei Y. Speer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulatory mechanisms in vascular calcification

(2010) Andrew P. Sage et al.   Nature Reviews Cardiology

Smooth Muscle Cells Give Rise to Osteochondrogenic Precursors and Chondrocytes in Calcifying Arteries

(2009) Mei Y. Speer et al.   CIRCULATION RESEARCH

Transcriptional networks controlling skeletal development

(2009) Christine Hartmann   CURRENT OPINION IN GENETICS & DEVELOPMENT

Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes

(2009) Satoshi Yamashita et al.   EXPERIMENTAL CELL RESEARCH

Functions of RANKL/RANK/OPG in bone modeling and remodeling

(2008) Brendan F. Boyce et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

(2008) Chang Hyun Byon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY