The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis

Endothelial cells and cancer cells

(2015) Annalisa Zecchin et al.   CURRENT OPINION IN HEMATOLOGY

Adrenomedullin Therapy in Patients with Refractory Ulcerative Colitis: A Case Series

(2015) Shinya Ashizuka et al.   DIGESTIVE DISEASES AND SCIENCES

Functional differentiation of RAMP2 and RAMP3 in their regulation of the vascular system

(2014) Akihiro Yamauchi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Adrenomedullin-RAMP2 System Is Crucially Involved in Retinal Angiogenesis

(2013) Yasuhiro Iesato et al.   AMERICAN JOURNAL OF PATHOLOGY

Vascular Endothelial Adrenomedullin-RAMP2 System Is Essential for Vascular Integrity and Organ Homeostasis

(2013) Teruhide Koyama et al.   CIRCULATION

Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci

(2013) Sachie Hiratsuka et al.   Nature Communications

Tie1 deficiency induces endothelial–mesenchymal transition

(2012) Julie Garcia et al.   EMBO REPORTS

The role of endothelial-mesenchymal transition in development and pathological process

(2012) Feng Lin et al.   IUBMB LIFE

Angiogenic roles of adrenomedullin through vascular endothelial growth factor induction

(2011) Takakuni Maki et al.   NEUROREPORT

Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis

(2011) T Tomita et al.   ONCOGENE

Angiogenic and Vasoprotective Effects of Adrenomedullin on Prevention of Cognitive Decline After Chronic Cerebral Hypoperfusion in Mice

(2011) Takakuni Maki et al.   STROKE

The First Clinical Pilot Study of Intravenous Adrenomedullin Administration in Patients With Acute Myocardial Infarction

(2010) Yu Kataoka et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

(2009) I. Sorensen et al.   BLOOD

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity

(2007) Yuka Ichikawa-Shindo et al.   JOURNAL OF CLINICAL INVESTIGATION