Sterically Shielded Heptamethine Cyanine Dyes for Bioconjugation and High Performance Near‐Infrared Fluorescence Imaging

A Nonaggregating Heptamethine Cyanine for Building Brighter Labeled Biomolecules

(2019) Michael P. Luciano et al.   ACS Chemical Biology

Approach to a Substituted Heptamethine Cyanine Chain by the Ring Opening of Zincke Salts

(2019) Lenka Štacková et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Emerging Fluorescent Molecular Tracers to Guide Intra-Operative Surgical Decision-Making

(2019) Pieterjan Debie et al.   Frontiers in Pharmacology

Isomerization and Dimerization of Indocyanine Green and a Related Heptamethine Dye

(2019) Franziska Rüttger et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Improved antibody-guided surgery with a near-infrared dye on a pegylated linker for CEA-positive tumors

(2019) Paul J. Yazaki et al.   JOURNAL OF BIOMEDICAL OPTICS

Latest developments in molecular tracers for fluorescence image-guided cancer surgery

(2019) Sophie Hernot et al.   LANCET ONCOLOGY

From Dyestuff Chemistry to Cancer Theranostics: The Rise of Rylenecarboximides

(2019) Chendong Ji et al.   ACCOUNTS OF CHEMICAL RESEARCH

Targeted molecular imaging of TLR4 in hepatocellular carcinoma using zwitterionic near-infrared fluorophores

(2019) Yuanyuan Ji et al.   Quantitative Imaging in Medicine and Surgery

Tailoring Kidney Transport of Organic Dyes with Low-Molecular-Weight PEGylation

(2019) Bujie Du et al.   BIOCONJUGATE CHEMISTRY

Paired Agent Fluorescence Imaging of Cancer in a Living Mouse Using Preassembled Squaraine Molecular Probes with Emission Wavelengths of 690 and 830 nm

(2019) Cynthia L. Schreiber et al.   BIOCONJUGATE CHEMISTRY

Repurposing Cyanine NIR-I Dyes Accelerates Clinical Translation of Near-Infrared-II (NIR-II) Bioimaging

(2018) Shoujun Zhu et al.   ADVANCED MATERIALS

An Efficient 1064 nm NIR-II Excitation Fluorescent Molecular Dye for Deep-Tissue High-Resolution Dynamic Bioimaging

(2018) Benhao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A chemically stable fluorescent marker of the ureter

(2018) Jaepyeong Cha et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, optical properties and cytotoxicity of meso -heteroatom substituted IR-786 analogs

(2018) Xiaozhong Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Effect of Fluorophore Conjugation on Antibody Affinity and the Photophysical Properties of Dyes

(2018) Ágnes Szabó et al.   BIOPHYSICAL JOURNAL

Non-Covalently Pre-Assembled High-Performance Near-Infrared Fluorescent Molecular Probes for Cancer Imaging

(2018) Scott Shaw et al.   CHEMISTRY-A EUROPEAN JOURNAL

The influence of systematic structure alterations on the photophysical properties and conjugation characteristics of asymmetric cyanine 5 dyes

(2018) S.J. Spa et al.   DYES AND PIGMENTS

Tricarbocyanine N-triazoles: the scaffold-of-choice for long-term near-infrared imaging of immune cells in vivo

(2018) Richard J. Mellanby et al.   Chemical Science

A zwitterionic near-infrared dye linked TrkC targeting agent for imaging metastatic breast cancer

(2018) Zhen Yang et al.   MedChemComm

Near-Infrared-II (NIR-II) Bioimaging via Off-Peak NIR-I Fluorescence Emission

(2018) Shoujun Zhu et al.   Theranostics

Harnessing Cyanine Reactivity for Optical Imaging and Drug Delivery

(2018) Alexander P. Gorka et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cyanine Conformational Restraint in the Far-Red Range

(2017) Megan S. Michie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of Dye and Conjugation Chemistry on the Biodistribution Profile of Near-Infrared-Labeled Nanobodies as Tracers for Image-Guided Surgery

(2017) Pieterjan Debie et al.   MOLECULAR PHARMACEUTICS

Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance

(2017) Cornelius Cilliers et al.   MOLECULAR PHARMACEUTICS

Molecular imaging of biological systems with a clickable dye in the broad 800- to 1,700-nm near-infrared window

(2017) Shoujun Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time near-infrared fluorescence imaging using cRGD-ZW800-1 for intraoperative visualization of multiple cancer types

(2017) Henricus J.M. Handgraaf et al.   Oncotarget

Tissue-Specific Near-Infrared Fluorescence Imaging

(2016) Eric A. Owens et al.   ACCOUNTS OF CHEMICAL RESEARCH

Conformational Switching of π-Conjugated Junctions from Merocyanine to Cyanine States by Solvent Polarity

(2016) Alhama Arjona-Esteban et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer

(2016) Anton Bunschoten et al.   BIOCONJUGATE CHEMISTRY

Recent Development of Chemosensors Based on Cyanine Platforms

(2016) Wen Sun et al.   CHEMICAL REVIEWS

Preparation of an18F-Labeled Hydrocyanine Dye as a Multimodal Probe for Reactive Oxygen Species

(2016) Salma Al-Karmi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tumor-Specific Uptake of Fluorescent Bevacizumab–IRDye800CW Microdosing in Patients with Primary Breast Cancer: A Phase I Feasibility Study

(2016) Laetitia E. Lamberts et al.   CLINICAL CANCER RESEARCH

Synthesis and systematic evaluation of symmetric sulfonated centrally C C bonded cyanine near-infrared dyes for protein labelling

(2016) Steffen van der Wal et al.   DYES AND PIGMENTS

Fluorescence guided surgery and tracer-dose, fact or fiction?

(2016) Gijs H. KleinJan et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Review of fluorescence guided surgery systems: identification of key performance capabilities beyond indocyanine green imaging

(2016) Alisha V. DSouza et al.   JOURNAL OF BIOMEDICAL OPTICS

Review on near-infrared heptamethine cyanine dyes as theranostic agents for tumor imaging, targeting, and photodynamic therapy

(2016) Changhong Shi et al.   JOURNAL OF BIOMEDICAL OPTICS

High-contrast Noninvasive Imaging of Kidney Clearance Kinetics Enabled by Renal Clearable Nanofluorophores

(2015) Mengxiao Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycerol-Based Contrast Agents: A Novel Series of Dendronized Pentamethine Dyes

(2015) Virginia Wycisk et al.   BIOCONJUGATE CHEMISTRY

Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates

(2015) Kazuhide Sato et al.   BIOCONJUGATE CHEMISTRY

The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications

(2015) Dongdong Su et al.   CHEMICAL COMMUNICATIONS

Tailored Near-Infrared Contrast Agents for Image Guided Surgery

(2015) Costyl N. Njiojob et al.   JOURNAL OF MEDICINAL CHEMISTRY

700-nm Zwitterionic Near-Infrared Fluorophores for Dual-Channel Image-Guided Surgery

(2015) Hoon Hyun et al.   MOLECULAR IMAGING AND BIOLOGY

Impact of C4′-O-Alkyl Linker on in Vivo Pharmacokinetics of Near-Infrared Cyanine/Monoclonal Antibody Conjugates

(2015) Kazuhide Sato et al.   MOLECULAR PHARMACEUTICS

Cyanine polyene reactivity: scope and biomedical applications

(2015) Alexander P. Gorka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Reactive species involved in the regioselective photooxidation of heptamethine cyanines

(2015) Roger R. Nani et al.   Chemical Science

A simple and effective “capping” approach to readily tune the fluorescence of near-infrared cyanines

(2015) Longwei He et al.   Chemical Science

Targeted zwitterionic near infrared fluorescent probe for improved imaging of type 2 cannabinoid receptors

(2014) Zhiyuan Wu et al.   JOURNAL OF BIOMEDICAL OPTICS

Tunable Heptamethine–Azo Dye Conjugate as an NIR Fluorescent Probe for the Selective Detection of Mitochondrial Glutathione over Cysteine and Homocysteine

(2014) Soo-Yeon Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Central C–C bonding increases optical and chemical stability of NIR fluorophores

(2014) Hoon Hyun et al.   RSC Advances

Targeted zwitterionic near-infrared fluorophores for improved optical imaging

(2013) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

cGMP-Compatible preparative scale synthesis of near-infrared fluorophores

(2012) Hoon Hyun et al.   Contrast Media & Molecular Imaging

Synthesis and In Vivo Fate of Zwitterionic Near-Infrared Fluorophores

(2011) Hak Soo Choi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rational Approach To Select Small Peptide Molecular Probes Labeled with Fluorescent Cyanine Dyes for in Vivo Optical Imaging

(2011) Mikhail Y. Berezin et al.   BIOCHEMISTRY

In Vivo Quantification of Tumor Receptor Binding Potential with Dual-Reporter Molecular Imaging

(2011) Kenneth M. Tichauer et al.   MOLECULAR IMAGING AND BIOLOGY

Development of photostable near-infrared cyanine dyes

(2010) Animesh Samanta et al.   CHEMICAL COMMUNICATIONS

Cyanine dyes in biophysical research: the photophysics of polymethine fluorescent dyes in biomolecular environments

(2010) Marcia Levitus et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Stabilisation of a heptamethine cyanine dye by rotaxane encapsulation

(2008) C. M. Simon Yau et al.   CHEMICAL COMMUNICATIONS