Article
Medicine, Research & Experimental
Riki Taitelbaum-Swead, Adi Pinhas, Shiraz Cohen Tsemah, Hagar Wechsler, Shai Chordekar
Summary: This study found no significant effect of COVID-19 infection on hearing thresholds, even among patients with additional COVID-19 symptoms, hypertension, diabetes, or smoking.
Article
Otorhinolaryngology
Divya A. Chari, Ayush Parikh, Elliott D. Kozin, Meaghan Reed, David H. Jung
Summary: The COVID-19 pandemic led to significant changes in the healthcare system, but did not appear to increase the risk of sudden sensorineural hearing loss (SSNHL) development.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Otorhinolaryngology
Milisavljevic Dusan, Stankovic Milan, Dordevic Nikola
Summary: This cross-sectional study aimed to investigate the potential link between COVID-19 infection and hearing loss. The study found that 40.5% of COVID-19 positive patients experienced sensorineural hearing loss, with statistically significant differences in frequencies across all age groups. Distribution of comorbidities did not show significant differences between patients with hearing loss and those with normal hearing.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Review
Medicine, General & Internal
Eldre Beukes, Alyssa Jade Ulep, Taylor Eubank, Vinaya Manchaiah
Summary: This review systematically analyzed studies on the impact of COVID-19 on tinnitus, finding that the prevalence of tinnitus post COVID-19 was estimated at 8%. Stress and anxiety associated with the pandemic were consistently suggested to contribute to tinnitus experiences, while no consistent patterns were found regarding the development of tinnitus in studies on disease impact.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Otorhinolaryngology
Badr Eldin Mostafa, Ahmed Mostafa, Lobna M. El Fiky, Abir Omara, Ahmed Teaima
Summary: This retrospective cohort study found that neonates born to Covid-19 positive mothers did not seem to have an increased risk of hearing loss. Further follow-up is necessary to detect any possible delayed effects of the virus on neonatal hearing.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Editorial Material
Otorhinolaryngology
Carolyn M. Jenks, Melinda DeSell, Jonathan Walsh
Summary: The COVID-19 pandemic has caused significant delays in early detection and intervention for congenital hearing loss, potentially impacting individual patients and public health. Healthcare providers have opportunities to mitigate the negative effects of the pandemic on pediatric hearing health care.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Review
Otorhinolaryngology
Esmaeil Mehraeen, Arian Afzalian, Amir Masoud Afsahi, Ramin Shahidi, Amirata Fakhfouri, Kiana Karimi, Sanaz Varshochi, Mohammad Amin Habibi, Ayoob Molla, Ali Dadjou, Zohreh Tajabadi, Khadijeh Nasiri, Seyed Ahmad Seyed Alinaghi, Daniel Hackett
Summary: This study aimed to investigate the manifestation of hearing loss from COVID-19. The findings suggest that despite being rare, hearing loss can impact a patient's quality of life. The most common type reported was sensorineural hearing loss, which can be diagnosed with variable techniques.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Ophthalmology
Alec Bernard, Sara Weiss, Moshiur Rahman, Sheryl S. Ulin, Clive D'Souza, Anah Salgat, Kate Panzer, Joshua D. Stein, Michelle A. Meade, Michael M. McKee, Joshua R. Ehrlich
Summary: The study revealed that the COVID-19 pandemic has significantly impacted individuals with sensory impairments, especially those with visual impairments facing more difficulties in daily activities. Efforts on targeted policy approaches are suggested to support this vulnerable population during the pandemic and future crises.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Review
Clinical Neurology
Kathiravan Kaliyappan, Yu-Chen Chen, Vijaya Prakash Krishnan Muthaiah
Summary: This review examines the vestibulocochlear manifestations following SARS-CoV-2 infections, discussing the prevalence, epidemiological and clinical features, and potential pathological mechanisms associated with these symptoms.
FRONTIERS IN NEUROLOGY
(2022)
Article
Otorhinolaryngology
Alejandro Garcia, Divya A. Chari, Konstantina M. Stankovic, Daniel J. Lee, Elliott D. Kozin, Kevin H. Franck
Summary: Mobile-based audiometry showed comparable results to conventional audiometry, making it a promising screening tool when traditional testing is not available.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Editorial Material
Medicine, General & Internal
Marie Perret, Angelique Bernard, Alan Rahmani, Patrick Manckoundia, Alain Putot
Summary: An 84-year-old man presented with acute vomiting, dizziness, and hearing loss, diagnosed with COVID-19 and right labyrinthitis. Treatment with oral corticosteroids led to gradual clinical recovery.
Article
Clinical Neurology
Ricardo R. Figueiredo, Norma de O. Penido, Andreia A. de Azevedo, Patricia M. de Oliveira, Adriana G. de Siqueira, Guilherme de M. R. Figueiredo, Winfried Schlee, Berthold Langguth
Summary: The study aimed to explore the relationship between COVID-19 and tinnitus by analyzing a sample of people in Volta Redonda, Brazil who had suffered from a COVID-19 infection. The results showed that patients with tinnitus onset before COVID-19 and those with tinnitus onset during or after COVID-19 did not differ significantly in their clinical characteristics and their hearing function, suggesting that tinnitus occurring in the context of a COVID-19 infection is not related to a unique pathophysiological mechanism.
FRONTIERS IN NEUROLOGY
(2022)
Review
Clinical Neurology
Xiangming Meng, Jing Wang, Jian Sun, Kangxu Zhu
Summary: There is a growing body of evidence suggesting that patients with COVID-19 have a risk of developing sudden sensorineural hearing loss (SSNHL). This systematic review examined the incidence of SSNHL in COVID-19 patients and their clinical characteristics. The findings show that there is inconsistency in the literature regarding whether COVID-19 increases the incidence of SSNHL.
FRONTIERS IN NEUROLOGY
(2022)
Article
Audiology & Speech-Language Pathology
Roberto Gallus, Andrea Melis, Laura Maria De Luca, Davide Rizzo, Sara Palmas, Emilia Degni, Antonio Piras, Francesco Bussu
Summary: Based on our study, the coronavirus disease 2019 pandemic has limited impact on our Universal Newborn Hearing Screening program. There was no significant difference in the variables analyzed, and the severe acute respiratory syndrome coronavirus 2 was not identified as an audiological risk factor in our series.
Article
Otorhinolaryngology
Arzu Kirbac, Handan Turan Dizdar, Ercan Kaya, Saziye Armagan Incesulu
Summary: A retrospective analysis of the hearing screening results of 36 infants with and without a history of intrauterine exposure to COVID-19 infection showed that exposure to COVID-19 infection in the intrauterine period does not cause congenital or late-onset hearing loss in infants.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2023)
Article
Pharmacology & Pharmacy
Ali Ozdemir, Levent Tumkaya, Suleyman Kalcan, Mikail Uyan, Ahmet Karakaya, Gokhan Demiral, Tugba Celik Samanci, Tolga Mercantepe, Medine Cumhur Cure, Erkan Cure
Summary: The study demonstrates that Infliximab can mitigate acute kidney injury induced by CCl4 by reducing the number of apoptotic cells and decreasing lipid peroxidation and oxidative stress. These findings suggest a promising ameliorating role of TNF-alpha inhibitors in acute kidney injury.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2022)
Editorial Material
Biochemistry & Molecular Biology
Erkan Cure, Medine Cumhur Cure
Summary: Lipids have various important functions in metabolism and cell structure, and their interaction with Na+/H+ Exchanger (NHE) may affect susceptibility to SARS-CoV-2 infection and severity of COVID-19. Further exploration of treatment regimens targeting NHE and lipids could be beneficial for COVID-19 management.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Pharmacology & Pharmacy
Rabia Aydogan Baykara, Pinar Diydem Yilmaz, Mevlut Hakan Goktepe, Cengiz Kadiyoran, Mustafa Ogul, Adem Kucuk, Medine Cumhur Cure, Erkan Cure
Summary: There is a strong independent association between subclinical atherosclerosis and PCSK9 in patients with Behcet's disease. However, there may be no independent association between PCSK9 and disease activity.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2022)
Review
Pharmacology & Pharmacy
Medine Cumhur Cure, Erkan Cure
Summary: The release of cytokines is increased in critically ill patients with COVID-19, leading to increased morbidity and mortality. SARS-CoV-2 virus triggers cytokine release through various mechanisms, including enhancing angiotensin II levels and stimulating Na+/H+ exchanger. Excessive cytokine release causes pathological problems and facilitates the spread and infection of the virus.
CURRENT PHARMACEUTICAL DESIGN
(2022)
Editorial Material
Endocrinology & Metabolism
E. Cure, M. Cumhur Cure
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Peripheral Vascular Disease
Filiz Mercantepe, Serap Baydur Sahin, Medine Cumhur Cure, Zakir Karadag
Summary: The study aimed to investigate the correlation between serum Endocan levels and the presence and severity of endothelial dysfunction, as well as its relationships with other markers. The results showed no correlation between serum Endocan values and endothelial dysfunction markers in obese women.
Article
Medicine, General & Internal
Sakir Gica, Yasemin Akkubak, Zakire Kubra Aksoy, Adem Kucuk, Erkan Cure
Summary: Patients with AS and RA experienced worsened psychological states compared to healthy controls, with perceived COVID threat and psychological status being associated with disease activity in AS but not RA patients. Those with chronic illnesses may be more susceptible to the psychological impacts of the pandemic, which can exacerbate disease activity.
TURKISH JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Pharmacology & Pharmacy
I Aydin, I Sehitoglu, E. Ozer, Y. Kalkan, L. Tumkaya, M. C. Cure, E. Cure
Summary: The study found that high-dose ZA may exacerbate liver injury during ischemia-reperfusion by increasing reactive oxygen species production and apoptosis.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Erkan Cure, Adem Kucuk, Medine Cumhur Cure
Summary: Although various potent drugs have been used for cytokine storm, mortality remains high for COVID-19 patients in the ICU. IFNs play a key role in both primary and secondary cytokine storms, with treatments like anakinra, tocilizumab, and JAK inhibitors being effective but sometimes inadequate. Emapalumab, a potent antagonist of IFN-gamma, could be a life-saving option for cases resistant to conventional treatments.
INDIAN JOURNAL OF PHARMACOLOGY
(2021)
Letter
Pharmacology & Pharmacy
Erkan Cure, Hakan Sirin, Medine Cumhur Cure, Dursun Ali Sahin
INDIAN JOURNAL OF PHARMACOLOGY
(2021)
Article
Otorhinolaryngology
Jason Lee, Alia Tayara, James D. Warren, Boris Kuyeb, Elizabeth McKee, Alexander Velazquez, Oishika Paul, Andrea F. Lewis
Summary: The purpose of the study was to understand the impact of COVID-19 on facial trauma incidence and etiology in Mississippi. The research found a significant increase in facial trauma caused by family members during the pandemic, which may be related to the reported increase in domestic violence. Additionally, there were notable changes in the etiology and insurance payor of facial trauma cases during the COVID-19 pandemic.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Sheila Moran, Cassidy Anderson, Risha Sheni, Monica Azmy, Daniel T. Li, Anthony M. Loizides, Christina J. Yang
Summary: This retrospective study found that a family history of eczema and a dairy-free diet may be associated with an increased risk of future diagnosis of EoE in children with aerodigestive dysfunction.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Robert Brinton Fujiki, Amanda Edith Fujiki, Susan L. Thibeault
Summary: This study examined the number of therapy sessions required for patients with EILO/ILO to sufficiently improve their symptoms. The results showed that patients with comorbid behavioral health diagnosis, higher vocal handicap index score, and reduced physical activity due to EILO/ILO symptoms required more therapy sessions. Patients with secondary environmental triggers also required more sessions. Only a small percentage of patients returned for additional therapy sessions after discharge, and they were mostly from affluent neighborhoods.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Brian W. Herrmann, Salina H. Goff, Juri Boguniewicz, Sarah A. Gitomer
Summary: This retrospective case series analyzed nHiB H. influenzae meningitis cases diagnosed at Children's Hospital Colorado from 2000 to 2020. The results showed that nHiB H. influenzae can cause both transient and permanent postmeningitic hearing loss. The use of steroids may offer otoprotection in nHiB H. influenzae meningitis. Further research is needed to better understand hearing outcomes after nHiB H. influenzae meningitis.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
M. Kovacs, J. Uzsaly, G. Bodzai, I. Pap, B. Lippai, T. Dergez, A. Nemeth, I. Gerlinger, I. Szanyi, P. Bako
Summary: The pathophysiology and treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) are still debated. A randomized controlled trial showed no significant differences in hearing improvement between different treatments, but identified clinical factors such as vertigo, cardiovascular comorbidity, and initial hearing loss severity as significant predictors of hearing outcomes.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Roee Noy, Yotam Shkedy, Nadeem Habashi, Salem Billan, Jacob Cohen
Summary: Salvage cordectomy offers favorable larynx preservation rates and oncological outcomes for recurrent glottic cancer amenable to conservative surgery. Smoking, advanced age, and advanced tumor stages are associated with salvage cordectomy failure.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Pietro De Luca, Ignazio La Mantia, Federico Maria Gioacchini, Massimo Re, Marco Radici, Angelo Camaioni, Arianna Di Stadio
Summary: In this study, the effect of nasal packaging using Fitostimoline (R) gauze on nasal outcomes after septoplasty and FESS surgery was evaluated. The results showed that the use of Fitostimoline (R) gauze improved healing of nasal mucosa and reduced discomfort during tampon removal.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Anna Frants, Antonios N. Varelas, Alexa M. Franco, W. Matthew White, Minas S. Constantinides, Philip J. Miller, Judy W. Lee
Summary: This article introduces DESS as a new educational format to increase the comfort of residents with the surgical evaluation and intraoperative planning of rhinoplasty. Through DESS, residents display significant improvement in their comfort with facial nasal analysis and overall surgical preparation.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Zhengcai Lou, Zihan Lou, Tian Lv, Zhengnong Chen
Summary: This study compared the operation time, graft success, audiometric outcomes, and complications of the over-under technique using temporalis fascia and cartilage grafts for repairing large perforations. The results showed that both techniques had similar graft success rates and hearing outcomes, but the temporalis fascia graft technique prolonged the operation time and increased the risk of re-perforation and graft atelectasis.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Review
Otorhinolaryngology
Ciaran Lane, Maxwell Wright, Janice Linton, Neerav Goyal
Summary: This study systematically reviewed the data on surgical closure of enlarged tracheoesophageal fistula after laryngectomy and compared different reconstruction techniques. The results showed that using vascularized tissue for reconstruction had a higher success rate compared to primary closure.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Review
Otorhinolaryngology
John Q. Odom, Andrew R. Mangan, Anna Celeste Gibson, Michael Larson, John L. Dornhoffer, Robert A. Saadi
Summary: Granulomatosis with polyangiitis is often associated with otolaryngologic complaints, and in rare cases, patients may experience facial nerve palsy. It is important for healthcare professionals to recognize facial nerve palsy as a potential presentation of granulomatosis with polyangiitis.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
R. Bar, A. Mattei, R. Haddad, A. Giovanni
Summary: Office-based flexible interventional laryngoscopy under local anesthesia is a safe and well-tolerated procedure, suitable for various ambulatory and office-based settings.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Review
Otorhinolaryngology
Do Hyun Kim, Soo Whan Kim, Sung Won Kim, Gulnaz Stybayeva, Se Hwan Hwang
Summary: This systematic review and meta-analysis compared the effects of cryotherapy and radiofrequency neurolysis in treating rhinitis-related symptoms caused by ablation of the posterior nasal nerves. The results showed that both cryotherapy and radiofrequency neurolysis significantly improved rhinitis-related symptoms and quality of life. Radiofrequency neurolysis was found to be more effective than cryotherapy in reducing total nasal symptom scores.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Mengdie Gao, Liyu Cheng, Qingcui Wang, Qingwen Yang, Xiaoyi Wang, Yanru Li, Rong Hu, Wen Xu
Summary: This study investigates the clinical characteristics, diagnosis, and prognosis of patients with laryngeal tuberculosis (LTB) combined with respiratory tuberculosis. The study found that LTB commonly affects middle-aged men and presents with symptoms such as hoarseness, abnormal sensation of pharyngeal, and pharyngalgia. The lesions mainly involve multiple subregions, primarily the glottis, and can also involve the pharynx. Half of the patients were complicated with pulmonary tuberculosis (PTB), and chest CT was superior to X-ray in detecting pulmonary lesions. Most patients showed significant improvement in symptoms and morphology of the pharyngeal and laryngeal mucosa after regular anti-tuberculosis treatment.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Alfonso Scarpa, Emilio Avallone, Mario Carucci, Giovanni Salzano, Giuseppe Chiarella, Claudia Cassandro, Pasquale Viola, Filippo Ricciardiello, Massimo Ralli, Pietro De Luca, Francesco Antonio Salzano
Summary: This study assessed the efficacy and safety of low-dose intratympanic gentamicin for vertigo attacks in Meniere's disease. The treatment significantly reduced vertigo attacks without causing hearing deterioration. The method primarily affected vestibular function while preserving cochlear integrity. These findings suggest that a low-dose, clinical symptomatology-based gentamicin treatment regimen could be an effective and safe strategy for managing unilateral Meniere's disease.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2024)
