MAPT haplotype–stratified GWAS reveals differential association for AD risk variants

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Metalloproteinases and their tissue inhibitors in Alzheimer’s disease and other neurodegenerative disorders

(2019) Santiago Rivera et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genetic variation in CADM2 as a link between psychological traits and obesity

(2019) Julia Morris et al.   Scientific Reports

Apolipoprotein E region molecular signatures of Alzheimer's disease

(2018) Alexander M. Kulminski et al.   AGING CELL

The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes

(2018) Ornit Chiba-Falek et al.   Alzheimers & Dementia

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

(2018) Mariet Allen et al.   Alzheimers & Dementia

Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses

(2018) Anatoliy I. Yashin et al.   EXPERIMENTAL GERONTOLOGY

Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE

(2018) Yann C. Klimentidis et al.   INTERNATIONAL JOURNAL OF OBESITY

The GABAergic System as a Therapeutic Target for Alzheimer's Disease

(2018) B Calvo-Flores Guzmán et al.   JOURNAL OF NEUROCHEMISTRY

Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents

(2018) Diana M. Ciuculete et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Sex and age interact to determine clinicopathologic differences in Alzheimer’s disease

(2018) Amanda M. Liesinger et al.   ACTA NEUROPATHOLOGICA

Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy

(2018) Mariet Allen et al.   ACTA NEUROPATHOLOGICA

The Role of Variation at AβPP, PSEN1, PSEN2, and MAPT in Late Onset Alzheimer's Disease

(2018) Amy Gerrish et al.   JOURNAL OF ALZHEIMERS DISEASE

Ordered Subset Analysis of Copy Number Variation Association with Age at Onset of Alzheimer's Disease

(2018) Kinga Szigeti et al.   JOURNAL OF ALZHEIMERS DISEASE

ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans

(2018) Olivia J Conway et al.   Molecular Neurodegeneration

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

(2018) Shan Jiang et al.   Translational Psychiatry

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

Meta-analysis of the association between variants in MAPT and neurodegenerative diseases

(2017) Cheng-Cheng Zhang et al.   Oncotarget

Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes

(2017) Chad S. Hunter et al.   Frontiers in Genetics

Atypical, non-standard functions of the microtubule associated Tau protein

(2017) Ioannis Sotiropoulos et al.   Acta Neuropathologica Communications

Genome-wide association study in essential tremor identifies three new loci

(2016) Stefanie H. Müller et al.   BRAIN

New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics

(2016) Michael W. Lutz et al.   Current Neurology and Neuroscience Reports

Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease

(2016) Kunie Ando et al.   NEUROBIOLOGY OF DISEASE

Molecular Pathogenic Basis forGABRG2Mutations Associated With a Spectrum of Epilepsy Syndromes, From Generalized Absence Epilepsy to Dravet Syndrome

(2016) Jing-Qiong Kang et al.   JAMA Neurology

Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases

(2016) Mariet Allen et al.   Scientific Data

A novel Alzheimer disease locus located near the gene encoding tau protein

(2015) G Jun et al.   MOLECULAR PSYCHIATRY

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

(2015) C A Ibrahim-Verbaas et al.   MOLECULAR PSYCHIATRY

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

(2015) Naomi Kouri et al.   Nature Communications

Conducting Meta-Analyses inRwith themetaforPackage

(2015) Wolfgang Viechtbauer   Journal of Statistical Software

Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

(2014) Mariet Allen et al.   Alzheimers Research & Therapy

Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease

(2014) Adam C. Naj et al.   JAMA Neurology

DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways

(2014) S Nardone et al.   Translational Psychiatry

Tau pathology and neurodegeneration

(2013) Maria Grazia Spillantini et al.   LANCET NEUROLOGY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Androgen receptor gene and sex-specific Alzheimer's disease

(2013) Raffaele Ferrari et al.   NEUROBIOLOGY OF AGING

Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

(2012) Fanggeng Zou et al.   PLoS Genetics

A Comprehensive Genetic Association Study of Alzheimer Disease in African Americans

(2011) Mark W. Logue   ARCHIVES OF NEUROLOGY

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

(2011) Günter U Höglinger et al.   NATURE GENETICS

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

ADAMTSL3 as a candidate gene for schizophrenia: Gene sequencing and ultra-high density association analysis by imputation

(2011) David J. Dow et al.   SCHIZOPHRENIA RESEARCH

Disentangling the Role of the Tau Gene Locus in Sporadic Tauopathies

(2010) J. Vandrovcova et al.   Current Alzheimer Research

Mechanisms of tau-induced neurodegeneration

(2009) Khalid Iqbal et al.   ACTA NEUROPATHOLOGICA

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS