Tuning the Local Availability of VEGF within Glycosaminoglycan‐Based Hydrogels to Modulate Vascular Endothelial Cell Morphogenesis

VEGF in Signaling and Disease: Beyond Discovery and Development

(2019) Rajendra S. Apte et al.   CELL

Growth factor delivery: Defining the next generation platforms for tissue engineering

(2019) Lilith M. Caballero Aguilar et al.   JOURNAL OF CONTROLLED RELEASE

Macroscale biomaterials strategies for local immunomodulation

(2019) Maxence O. Dellacherie et al.   Nature Reviews Materials

A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs

(2018) Joris Pauty et al.   EBioMedicine

Minimum structural requirements for BMP-2-binding of heparin oligosaccharides

(2018) Raymond A.A. Smith et al.   BIOMATERIALS

In situ-forming, cell-instructive hydrogels based on glycosaminoglycans with varied sulfation patterns

(2018) Passant Atallah et al.   BIOMATERIALS

The particle in the spider's web: transport through biological hydrogels

(2017) Jacob Witten et al.   Nanoscale

Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice

(2017) Nadine Lohmann et al.   Science Translational Medicine

Matrix degradability controls multicellularity of 3D cell migration

(2017) Britta Trappmann et al.   Nature Communications

Multiscale microenvironmental perturbation of pluripotent stem cell fate and self-organization

(2017) Yoji Tabata et al.   Scientific Reports

Glycosaminoglycan-Based Biohybrid Hydrogels: A Sweet and Smart Choice for Multifunctional Biomaterials

(2016) Uwe Freudenberg et al.   ADVANCED MATERIALS

Hybrid Polycaprolactone/Alginate Scaffolds Functionalized with VEGF to Promote de Novo Vessel Formation for the Transplantation of Islets of Langerhans

(2016) Giulia Marchioli et al.   Advanced Healthcare Materials

StarPEG-Heparin Hydrogels to Protect and Sustainably Deliver IL-4

(2016) Lucas Schirmer et al.   Advanced Healthcare Materials

Effect of Selective Heparin Desulfation on Preservation of Bone Morphogenetic Protein-2 Bioactivity after Thermal Stress

(2015) Song P. Seto et al.   BIOCONJUGATE CHEMISTRY

Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity

(2015) Madelane Teran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular weight and concentration of heparin in hyaluronic acid-based matrices modulates growth factor retention kinetics and stem cell fate

(2015) Amit K. Jha et al.   JOURNAL OF CONTROLLED RELEASE

Mathematical model accurately predicts protein release from an affinity-based delivery system

(2015) Katarina Vulic et al.   JOURNAL OF CONTROLLED RELEASE

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

(2015) Uwe Freudenberg et al.   JOURNAL OF CONTROLLED RELEASE

Simultaneous or Sequential Orthogonal Gradient Formation in a 3D Cell Culture Microfluidic Platform

(2015) Sebastien G. M. Uzel et al.   Small

Heparan Sulfate Proteoglycans Regulate Fgf Signaling and Cell Polarity during Collective Cell Migration

(2015) Marina Venero Galanternik et al.   Cell Reports

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

(2014) M. M. Martino et al.   SCIENCE

Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models

(2014) Karolina Chwalek et al.   Scientific Reports

Defined Polymer-Peptide Conjugates to Form Cell-Instructive starPEG-Heparin Matrices In Situ

(2013) Mikhail V. Tsurkan et al.   ADVANCED MATERIALS

Control of Perfusable Microvascular Network Morphology Using a Multiculture Microfluidic System

(2013) Jordan A. Whisler et al.   TISSUE ENGINEERING PART C-METHODS

Using Mean Field Theory to Guide Biofunctional Materials Design

(2012) Uwe Freudenberg et al.   ADVANCED FUNCTIONAL MATERIALS

Spatial control of cell-mediated degradation to regulate vasculogenesis and angiogenesis in hyaluronan hydrogels

(2012) Donny Hanjaya-Putra et al.   BIOMATERIALS

Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

(2012) Susanne A.I. Seidel et al.   METHODS

On the Specificity of Heparin/Heparan Sulfate Binding to Proteins. Anion-Binding Sites on Antithrombin and Thrombin Are Fundamentally Different

(2012) Philip D. Mosier et al.   PLoS One

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sprouting Angiogenesis under a Chemical Gradient Regulated by Interactions with an Endothelial Monolayer in a Microfluidic Platform

(2011) Gi Seok Jeong et al.   ANALYTICAL CHEMISTRY

Binding affinities of vascular endothelial growth factor (VEGF) for heparin-derived oligosaccharides

(2011) Wenjing Zhao et al.   BIOSCIENCE REPORTS

Bioactivity screening of partially desulfated low-molecular-weight heparins: A structure/activity relationship study

(2011) Sucharita Roy et al.   GLYCOBIOLOGY

In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients

(2011) Yoojin Shin et al.   LAB ON A CHIP

Mechanisms of Vascular Endothelial Growth Factor-Induced Pathfinding by Endothelial Sprouts in Biomaterials

(2011) Amir Shamloo et al.   TISSUE ENGINEERING PART A

FGF-2 and VEGF functionalization of starPEG–heparin hydrogels to modulate biomolecular and physical cues of angiogenesis

(2010) Andrea Zieris et al.   BIOMATERIALS

Multiple mechanisms for exogenous heparin modulation of vascular endothelial growth factor activity

(2010) Errol Wijelath et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

VEGF and endothelial guidance in angiogenic sprouting

(2010) Holger Gerhardt   Organogenesis

A star-PEG–heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases

(2009) Uwe Freudenberg et al.   BIOMATERIALS

Scaffolds with covalently immobilized VEGF and Angiopoietin-1 for vascularization of engineered tissues

(2009) Loraine L.Y. Chiu et al.   BIOMATERIALS

Covalently-Immobilized Vascular Endothelial Growth Factor Promotes Endothelial Cell Tubulogenesis in Poly(ethylene glycol) Diacrylate Hydrogels

(2009) Julia E. Leslie-Barbick et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics

(2009) Ferdinand Brandl et al.   JOURNAL OF CONTROLLED RELEASE

Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7

(2008) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Friendly fire against neutrophils: Proteolytic enzymes confuse the recognition of apoptotic cells by macrophages

(2007) Krzysztof Guzik et al.   BIOCHIMIE