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Recent Advances in Smart Biomaterials for the Detection and Treatment of Autoimmune Diseases

Journal

ADVANCED FUNCTIONAL MATERIALS
Volume 30, Issue 37, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adfm.201909556

Keywords

biomaterials; drug delivery; polymeric materials; sensors; biosensing; stimuli-responsive materials; tissue engineering

Funding

  1. National Institutes of Health [R01-EB022025, R01-EB-00246-21]
  2. National Science Foundation [1033746]
  3. Cockrell Family Regents Chair Foundation
  4. Office of the Dean of the Cockrell School of Engineering at the University of Texas at Austin (UT)
  5. Institute for Biomaterials, Drug Delivery, and Regenerative Medicine
  6. U.S. National Science Foundation Graduate Research Fellowships [DGE-1610403]

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Autoimmune diseases are a group of debilitating illnesses that are often idiopathic in nature. The steady rise in the prevalence of these conditions warrants new approaches for diagnosis and treatment. Stimuli-responsive biomaterials also known as smart, intelligent, or recognitive biomaterials are widely studied for their applications in drug delivery, biosensing, and tissue engineering due to their ability to produce thermal, optical, chemical, or structural changes upon interacting with the biological environment. Studies within the last decade that harness the recognitive capabilities of these biomaterials toward the development of novel detection and treatment options for autoimmune diseases are critically analyzed.

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