Article
Chemistry, Physical
Lijuan Wang, Yushuang Shang, Jie Zhang, Jiang Yuan, Jian Shen
Summary: The development of keratin-based biomaterials provides a valuable approach for addressing environmental pollutants and transforming waste into wealth. The properties and biomedical applications of keratin biomaterials, such as drug delivery, wound healing, and tissue engineering, are extensively discussed in this review, offering valuable insights for further research and development.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Review
Pharmacology & Pharmacy
Hossein Omidian, Sumana Dey Chowdhury, Niloofar Babanejad
Summary: Cryogels, versatile biomaterials composed of synthetic and natural materials, have wide applications in tissue engineering, drug delivery, regenerative medicine, and therapeutics. However, optimizing cryogel properties remains challenging, and researchers are exploring advanced manufacturing techniques and addressing long-term stability. Combination therapies and drug delivery systems using cryogels show promise, but in vivo evaluation and clinical trials are crucial for determining safety and efficacy. Overcoming practical challenges such as scalability, structural integrity, mass transfer constraints, biocompatibility, seamless integration, and cost-effectiveness is essential for the successful application of cryogels in biomedical fields.
Review
Polymer Science
Anahita Rohani Shirvan, Alireza Nouri, Alessandra Sutti
Summary: In the past decade, there has been significant growth in the use of fibre-based products and structures for biomedical applications. This review provides an overview of wet spinning, the effects of process parameters, and novel wet spinning-based manufacturing techniques. The potential applications of wet-spun fibrous structures in various medical fields are also discussed.
EUROPEAN POLYMER JOURNAL
(2022)
Review
Chemistry, Applied
Masoud Hamidi, Oseweuba Valentine Okoro, Peiman Brouki Milan, Mohammad Reza Khalili, Hadi Samadian, Lei Nie, Amin Shavandi
Summary: Fungal exopolysaccharides have diverse potential applications in various industries. However, there are only a few commercialized products based on fungal EPSs in the biomedical field. This review critically discusses the potential biomedical applications of fungal EPSs in tissue engineering, drug and gene delivery.
CARBOHYDRATE POLYMERS
(2022)
Review
Engineering, Biomedical
Susmita Bose, Naboneeta Sarkar, Dishary Banerjee
Summary: With an aging population and increasing life expectancy, orthopedic defects and bone graft surgeries are on the rise globally. The integration of natural medicinal compounds into bone scaffolds shows promising potential in guiding bone regeneration and healing processes.
ACTA BIOMATERIALIA
(2021)
Review
Biochemistry & Molecular Biology
Farzad Seidi, Mohsen Khodadadi Yazdi, Maryam Jouyandeh, Midhun Dominic, Haleh Naeim, Mojtaba Nasiri Nezhad, Babak Bagheri, Sajjad Habibzadeh, Payam Zarrintaj, Mohammad Reza Saeb, Masoud Mozafari
Summary: Polysaccharides are abundant carbohydrate polymers, with chitosan being the most widely used; blending chitosan with other polymers can improve its properties and bioactivity. This review paper summarizes progress in chitosan blends with biodegradable polymers and polysaccharides for biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Pharmacology & Pharmacy
Peixing Chen, Xiaoling Liao
Summary: This review provides an overview of kartogenin-functionalized biomaterials, focusing on their design, structure, functions, and applications in regenerative medicine. The physicochemical properties and biological functions of kartogenin are discussed, and recent advancements in materials for its carriage and delivery are explored. Opportunities and challenges in biomaterial developments and prospects for tissue regeneration are addressed.
Article
Engineering, Biomedical
Jia Liu, Lin Shi, Yan Deng, Meizhen Zou, Bo Cai, Yu Song, Zheng Wang, Lin Wang
Summary: Silk sericin, a natural protein with superior biological activities and controllable chemical-physical properties, has been extensively utilized in the biomedical field. Its versatile constructs formed through chemical modification and cross-linking make it an alternative matrix for biomedical applications.
Review
Pharmacology & Pharmacy
Almudena Naharros-Molinero, Maria Angela Caballo-Gonzalez, Francisco Javier de la Mata, Sandra Garcia-Gallego
Summary: This review provides an overview of the main parameters affecting the micellization process of Pluronics and presents common techniques for characterizing the structure and properties of the micelles. It also discusses approaches to improving the stability and drug loading of Pluronic micelles, with a focus on reverse Pluronics and reverse micelles which have been underexplored in the literature.
Review
Biochemistry & Molecular Biology
Girolamo Casella, Silvia Carlotto, Francesco Lanero, Mirto Mozzon, Paolo Sgarbossa, Roberta Bertani
Summary: Cyclic and polyphosphazenes are substrates characterized by -P=N- repeating units, which can be easily substituted with organic groups to create new materials for industrial applications. They have promising biomedical applications, such as antimicrobial agents in drug delivery and immunoadjuvants in tissue engineering. Their properties can be tailored by the number of repetitive units and the nature of the substituent groups.
Review
Biochemistry & Molecular Biology
Sara La Manna, Concetta Di Natale, Valentina Onesto, Daniela Marasco
Summary: Self-assembling peptides are a novel class of agents with versatile applications in the biomedical field. They exhibit biocompatibility and molecular recognition capabilities, making them suitable for drug delivery and tissue engineering purposes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Sakshi Priya, Unnati Batra, B. N. Samshritha, Sudhanshu Sharma, Akash Chaurasiya, Gautam Singhvi
Summary: Nanofibers are fibrous nanocarriers that can be synthesized from various materials, including natural polymers. Natural polysaccharides-based nanofibers have gained attention in pharmaceutical and biomedical applications due to their biocompatibility, biodegradability, non-toxicity, and economic advantages. However, there is a lack of research on the scale-up and advanced therapeutic delivery of nanofibers.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Polymer Science
Andreia S. Silva, Elisabete C. Costa, Sara Reis, Carina Spencer, Ricardo C. Calhelha, Sonia P. Miguel, Maximiano P. Ribeiro, Lillian Barros, Josiana A. Vaz, Paula Coutinho
Summary: Sericin, a potential biomaterial derived from silk, possesses various beneficial properties such as biocompatibility, anti-inflammatory, and antibacterial effects. It finds applications in biomedical and pharmaceutical fields, and its proper disposal could have positive economic, social, and environmental impacts.
Review
Biochemistry & Molecular Biology
Sabbir Ansari, Neha Sami, Durdana Yasin, Nazia Ahmad, Tasneem Fatma
Summary: Polyhydroxyalkanoates (PHA) are biological polyesters of hydroxyacids, considered as environmentally friendly alternatives to petroleum-based plastics, with biodegradability and biocompatibility. Research on different PHA in cell culture systems or animal hosts in recent years has shown their potential for applications in medical devices.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Rajesh Kumar, Dinesh Pratap Singh, Romina Munoz, Mongi Amami, Rajesh Kumar Singh, Shipra Singh, Vinod Kumar
Summary: This review article introduces the potential and research progress of graphene and its derivatives in biomedical applications, and summarizes their effects on human health and the environment.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Morteza Motahari Rad, Nahid Bijeh, Seyyed Reza Attarzadeh Hosseini, Aliakbar Raouf Saeb
Summary: This study investigated the effects of different sequences of concurrent training on adults with type 2 diabetes mellitus. The results showed that regardless of the sequence, concurrent training increased irisin and FST concentrations while decreasing MSTN concentrations. Additionally, concurrent training improved body composition, strength, and peak oxygen uptake.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Review
Biotechnology & Applied Microbiology
Negin Jalilinejad, Mohammad Rabiee, Nafiseh Baheiraei, Ramin Ghahremanzadeh, Reza Salarian, Navid Rabiee, Omid Akhavan, Payam Zarrintaj, Aleksander Hejna, Mohammad Reza Saeb, Ali Zarrabi, Esmaeel Sharifi, Satar Yousefiasl, Ehsan Nazarzadeh Zare
Summary: Human cardiac tissue lacks proper self-regenerating capability, making tissue engineering critical for addressing the growing rate of deaths associated with cardiovascular disorders. Carbon-based nanomaterials, specifically their conductivity, have revolutionized tissue engineering by providing an appropriate microenvironment for cell protection against attacking mechanisms. The use of conductive biomaterials in cardiac tissue engineering, including graphene, graphene oxide, carbon nanotubes, and carbon nanofibers, has been studied extensively.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2023)
Correction
Chemistry, Multidisciplinary
Narendra Pal Singh Chauhan, Masoud Mozafari, Narendra Singh Chundawat, Kiran Meghwal, Rakshit Ameta, Suresh C. Ameta
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Gonzalo Garcia-Espejo, Konstantis F. Konidaris, Pietro Anzini, Stefano Brenna, Antonietta Guagliardi, Norberto Masciocchi
Summary: The discovery and characterization of 1D and 2D lead halide polycrystalline solids and their perovskite analogues are of fundamental importance in the scientific community. The study reports the synthesis and full characterization of these materials, including their anisotropic thermal responses. Thin films were also prepared and studied using various experimental techniques.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Shukufe Amukarimi, Iman Mobasherpour, Sorosh Abdollahi, Peiman Brouki Milan, Masoud Mozafari
Summary: Thanks to prophylactic antibiotics, the risk of wound infection in orthopedic surgeries has significantly decreased. This study focuses on the effectiveness of a new biodegradable antibiotic-loaded coating on the surface of a magnesium implant. The results show that the coating is biocompatible, antibacterial, and has improved corrosion resistance, making it potentially suitable for bone regeneration applications.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Correction
Nanoscience & Nanotechnology
Navid Rabiee, Mojtaba Bagherzadeh, Amir Mohammad Ghadiri, Yousef Fatahi, Abdullah Aldhaher, Pooyan Makvandi, Rassoul Dinarvand, Maryam Jouyandeh, Mohammad Reza Saeb, Masoud Mozafari, Mohammadreza Shokouhimehr, Michael R. Hamblin, Rajender S. Varma
ACS APPLIED BIO MATERIALS
(2023)
Article
Engineering, Biomedical
Ali Sadeghi, Ehsan Afshari, Mohadeseh Hashemi, David Kaplan, Masoud Mozafari
Summary: Neural interfaces (NIs) are neuroengineering tools that enable a mutual communication pathway with the nervous system. Smart biomaterials (SBMs) such as stimuli-responsive and shape memory biomaterials emerged as novel materials with exceptional properties, enhancing the function of NIs and opening new possibilities in neuroscience studies and neuromodulation therapies.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Engineering, Biomedical
Mir Saman Safavi, Aydin Bordbar-Khiabani, Frank C. Walsh, Masoud Mozafari, Jafar Khalil-Allafi
Summary: NiTi metallic biomaterials have a wide range of clinical applications, and the use of NiTi smart biomaterials has gained attention for their unique features. Surface-modification techniques, including dry and wet coating techniques, have been employed to improve the biological properties of NiTi before clinical use. R&D activities have shown progress, but more work needs to be done before coated-NiTi can be used clinically.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Gonzalo Garcia-Espejo, Konstantis F. Konidaris, Antonietta Guagliardi, Norberto Masciocchi
Summary: The synthesis and structural characterization of two novel hybrid lead bromide perovskites, combining the imidazolium cation with methylammonium or formamidinium cations, were reported. The obtained compounds, (IMI)(MA)Pb2Br6 and (IMI)(FA)PbBr4, exhibited different structural features. The thermal stability of both compounds was investigated and showed chemical stability up to at least 250°C. The structural modification of (IMI)(FA)PbBr4 occurring above 100°C was also identified.
CHEMISTRY-SWITZERLAND
(2023)
Article
Chemistry, Multidisciplinary
Konstantis F. Konidaris, Marco Zambra, Francesco Giannici, Antonietta Guagliardi, Norberto Masciocchi
Summary: Perylene diimides (PDI) are widely used in organic electronics due to their n-semiconducting properties. This study demonstrates that 1,7-dibromo-substituted PDI molecules can be flattened in the solid state by forming pi-pi stabilized chains. This strategy can be applied to induce flat polyaromatic cores of different kinds in order to improve electronic performances.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biochemistry & Molecular Biology
Christian E. Rusbjerg-Weberskov, Mette Liere Johansen, Jan S. Nowak, Daniel E. Otzen, Jan Skov Pedersen, Jan J. Enghild, Nadia Sukusu Nielsen
Summary: Human periostin is a matricellular protein that plays important roles in extracellular matrix remodeling, tumor development, and inflammatory diseases. The C-terminal domain of periostin interacts with other domains and proteins, potentially contributing to the pathogenesis of diseases such as atopic dermatitis.
Article
Chemistry, Multidisciplinary
Fabio Ferri, Maria Chiara Bossuto, Pietro Anzini, Antonio Cervellino, Antonietta Guagliardi, Federica Bertolotti, Norberto Masciocchi
Summary: The Debye scattering equation (DSE) is widely used for analyzing total scattering data of nanocrystalline materials. In its modified form (MDSE), contributions from uncorrelated thermal agitation terms and average site-occupancy factors (s.o.f.'s) are included for defective crystalline nanoparticles (NPs). This paper provides a theoretical demonstration of the s.o.f.'s and corrects a glitch in the original MDSE, discussing their physical significance. Three new MDSE expressions are introduced for distinct defective NP ensembles, and the beneficial aspects and shortcomings of introducing s.o.f.'s as refinable parameters are demonstrated through numerical simulations and atomistic modeling.
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
(2023)
Article
Engineering, Biomedical
Hanieh Shokrani, Amirhossein Shokrani, Farzad Seidi, Justyna Kucinska-Lipka, Balbina Makurat-Kasprolewicz, Mohammad Reza Saeb, Seeram Ramakrishna
Summary: The concept of 'making computers think like people' is supported by computer-aided concepts, cognitive algorithms, fuzzy sets, and fuzzy logic thoughts. This idea enables the development of biomaterials and biosystems with the aid of Artificial Intelligence (AI). In the field of PSA-based biomedical engineering, AI-based algorithms play an important role in improving performance and optimizing scenarios.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Physics, Multidisciplinary
Nuri Yazdani, Maryna I. Bodnarchuk, Federica Bertolotti, Norberto Masciocchi, Ina Fureraj, Burak Guzelturk, Benjamin L. Cotts, Marc Zajac, Gabriele Raino, Maximilian Jansen, Simon C. Boehme, Maksym Yarema, Ming-Fu Lin, Michael Kozina, Alexander Reid, Xiaozhe Shen, Stephen Weathersby, Xijie Wang, Eric Vauthey, Antonietta Guagliardi, Maksym V. Kovalenko, Vanessa Wood, Aaron M. Lindenberg
Summary: Understanding the electron-phonon coupling in lead halide perovskites is important for interpreting and utilizing their optical and electronic properties. This study shows that photoexcitation leads to lattice reorganization through deformation potential coupling to low-energy optical phonons. The coupling strength is stronger in FAPbBr3 due to its disordered crystal structure. The reorganizations induced by each exciton in a multi-excitonic state constructively interfere, resulting in a coupling strength that scales quadratically with the exciton number.