Article
Psychiatry
Naoki Hashimoto, Hiroko Takeda, Yutaka Fujii, Yuriko Suzuki, Takahiro A. Kato, Daisuke Fujisawa, Kumi Aoyama-Uehara, Kotaro Otsuka, Nobuyuki Mitsui, Satoshi Asakura, Ichiro Kusumi
Summary: A study on 81 university teachers found that those who participated in the gatekeeper training program showed significant improvement in competence and confidence in managing suicidal students, as well as higher program satisfaction scores, compared to those who received a general mental health lecture. Active participant involvement was identified as crucial for effective suicide prevention training.
ASIAN JOURNAL OF PSYCHIATRY
(2021)
Article
Public, Environmental & Occupational Health
Carolyn Oldham, Kristie Guffey, Kim Link, Shannon Sampson, Tyler McQueen, Anna Stanton
Summary: Farmers have higher rates of psychological distress and suicide compared to workers in other industries. Gatekeeper programs, recognized as best practices for suicide prevention, train individuals to recognize warning signs of suicidal ideations. However, it remains a challenge to develop these programs in communities with stigma and taboo around mental health and suicide.
JOURNAL OF AGROMEDICINE
(2023)
Article
Psychiatry
Jacinta Hawgood, Yu Wen Koo, Jerneja Sveticic, Diego De Leo, Kairi Kolves
Summary: The Wesley LifeForce training showed positive impacts on the capabilities, attitudes, and intervention willingness of community workers, especially those without prior training. There was no significant difference in effectiveness between the half-day and full-day training formats in the short term.
FRONTIERS IN PSYCHIATRY
(2021)
Review
Psychology, Multidisciplinary
Janaina Minelli De Oliveira, Jorge-Manuel Duenas, Fabia Morales-Vives, Elena Gallardo-Nieto
Summary: The study reveals the importance of involving various educational stakeholders in suicide prevention, intervention, and postvention efforts from primary education to college level. It also highlights the different programs implemented in various countries and the gaps existing in research on suicide in the educational field. Overall, educational suicide initiatives have shown positive effects on participants' understanding and attitudes towards suicide prevention, despite some cautious findings in some studies.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychiatry
Jacinta Hawgood, Alan Woodward, Paul Quinnett, Diego De Leo
Summary: Gatekeeper training (GKT) is widely used in suicide prevention strategies, although there is a lack of research supporting its causal link to reduced suicide rates. However, studies suggest that GKT improves knowledge, skills, and confidence in helping individuals at risk of suicide.
CRISIS-THE JOURNAL OF CRISIS INTERVENTION AND SUICIDE PREVENTION
(2022)
Article
Public, Environmental & Occupational Health
Abby E. Beatty, John S. Richardson, Sonja V. Batten, Steven Weintraub, Karen Hogan, Keith Hotle
Summary: Despite public resources being invested in tackling the high suicide rates among veterans, little is known about how veterans and service members communicate suicidal thoughts during times of crisis, and what interventions they are willing to seek. This study aimed to identify communication and suicide intervention preferences among veterans and service members in crisis. The findings showed that veterans prefer to reach out to family members and military friends rather than crisis lines or veterans organizations. The preferred interventions varied based on participant demographics such as age, marital status, and veterans status. The study highlights the need for evidence-based, multimodal interventions to support veterans in need.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Maryam Masoomi, Seyedehmahboobeh Hosseinikolbadi, Fahimeh Saeed, Vandad Sharifi, Amir Hossein Jalali Nadoushan, Sheikh Shoib
Summary: Suicide and suicide attempt have a significant impact on a portion of the general population, but the stigma surrounding this issue remains a problem, particularly in lower-income countries like Iran. Help-seeking for suicidal individuals is low in Iran due to fear of stigma associated with loss of faith, severe mental illness, and unacceptable sexual relationships. Public stigma poses a greater obstacle to accessing care for suicidal thoughts or attempts, leading many individuals to miss out on support programs. This article addresses the challenges of public stigma in Iranian society and proposes culturally appropriate strategies to improve the situation.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Nursing
Elissa Dabkowski, Joanne E. Porter
Summary: This review evaluated the impact of suicide prevention programmes and found variances in the types of interventions, from single workshops to multimodal and organizational approaches. Further long-term research is needed to assess the implementation and effectiveness of suicide prevention programmes in healthcare, with a recommendation to enhance cultural awareness in suicide prevention training.
INTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING
(2021)
Article
Psychiatry
Brenda K. Ochuku, Natalie E. Johnson, Tom L. Osborn, Christine M. Wasanga, David M. Ndetei
Summary: Globally, over 800,000 people die by suicide every year, while there are even more attempts. Seeking help in moments of crisis, especially after a suicide attempt, plays a crucial role in suicide prevention. However, the criminalization of suicide in some countries obstructs help-seeking, increases stigma towards those who attempt suicide, and hinders accurate tracking of suicides. Therefore, evidence-based strategies such as means restriction, improved mental health literacy and access to psychosocial support, and responsible media coverage of suicides should be implemented.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychiatry
Chengxi Cai, Diyang Qu, Dongyu Liu, Bowen Liu, Xuan Zhang, Peiyu Chen, Dongyang Chen, Chen Yin, Shufang Sun, Yongsheng Tong, Jing An, Runsen Chen
Summary: To address the issue of contemporary suicide rates, an effective Life Gatekeeper training program was developed to educate school teachers in identifying and intervening with at-risk students. Two studies showed the program's effectiveness in improving suicide literacy, reducing stigma, and increasing willingness to intervene among gatekeepers. The practical application of the standardized video-based 'Train-the-trainer' approach proved particularly effective.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Samuel Rothman, Leo Sher
Summary: The COVID-19 pandemic has led to a rise in mental health issues such as anxiety, depression, self-harm, and suicide attempts, necessitating multi-level suicide prevention measures including universal, selective, and indicated prevention. Support from governments, banks, and other institutions can help the general population, but more targeted approaches are needed for high-risk individuals.
PREVENTIVE MEDICINE
(2021)
Article
Psychiatry
Jacinta Hawgood, Tamara Ownsworth, Kairi Kolves, Susan H. Spence, Ella Arensman, Diego De Leo
Summary: This study aims to examine the relationship between clinician characteristics and pre-training competencies in suicide risk assessment (SRA), as well as the impact of STARS training workshop on clinician competencies, and to determine the predictors of SRA training outcomes.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Health Care Sciences & Services
Amanda N. Stover, Jill E. Lavigne, Alexis Shook, Catherine MacAllister, Wendi F. Cross, Delesha M. Carpenter
Summary: This study aimed to co-design a 30-minute online training module (Pharm-SAVES) for community pharmacy staff to recognize suicide warning signs and refer at-risk individuals to appropriate care. By actively engaging stakeholders throughout the design process, researchers were able to create training content that was realistic and relevant to the needs of pharmacy staff. Currently, Pharm-SAVES is being evaluated in a pilot randomized controlled trial to assess its impact on pharmacy staff's suicide prevention communication behaviors.
HEALTH EXPECTATIONS
(2023)
Review
Psychiatry
Glenn Holmes, Amanda Clacy, Daniel F. Hermens, Jim Lagopoulos
Summary: Gatekeeper training has shown lasting effects on knowledge and self-efficacy, but knowledge may decay over time; attitudes of gatekeepers tend to return to baseline levels at follow-up; however, behavioral intention and actual behavior display weak training effects.
ARCHIVES OF SUICIDE RESEARCH
(2021)
Article
Psychology, Educational
Guy Diamond, Lawrence Ogunkua, Tita Atte, Perri Rosen, Matt Wintersteen, Robert Gallop
Summary: The study evaluated the effectiveness of the More Than Sad program in improving suicide literacy and willingness to refer at-risk youth in school personnel. Results showed a significant increase in knowledge, preparedness, self-efficacy, and likelihood to refer among trained staff, with gains maintained at the 2-month follow-up. Future research should explore the implementation feasibility and effectiveness of the pre-recorded training on DVDs.
SCHOOL MENTAL HEALTH
(2021)
Article
Clinical Neurology
Junya Matsumoto, Kenichiro Miura, Masaki Fukunaga, Kiyotaka Nemoto, Daisuke Koshiyama, Naohiro Okada, Kentaro Morita, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Satsuki Ito, Naomi Hasegawa, Yoshiyuki Watanabe, Kiyoto Kasai, Ryota Hashimoto
Summary: Patients with schizophrenia may experience intelligence decline, and previous studies have suggested that gray matter structures and functional connectivity are more relevant to this decline than white matter microstructures.
CLINICAL EEG AND NEUROSCIENCE
(2023)
Article
Psychology, Multidisciplinary
Keisuke Kokubun, Yoshinori Yamakawa, Kiyotaka Nemoto
Summary: Motivation and empathy are fundamental elements of human interaction and are associated with organizational performance, academic achievements, and the human brain. This study used GM-BHQ to evaluate the association of motivation and empathy with the whole brain and found that GM-BHQ is most sensitive to motivation levels and moderately sensitive to self-monitoring and certain subscales of empathic concern.
CURRENT PSYCHOLOGY
(2023)
Article
Geriatrics & Gerontology
Haruhiko Midorikawa, Saori Ekoyama, Hirokazu Tachikawa, Miho Ota, Masashi Tamura, Takumi Takahashi, Aya Sekine, Masayuki Ide, Asaki Matsuzaki, Miyuki Nemoto, Kiyotaka Nemoto, Tetsuaki Arai
Summary: This study examined the differences in behavioral and psychological symptoms of dementia (BPSD) between individuals living at home and those in institutional settings. The results showed that sleep disturbances were more common in patients with AD living in institutions.
Article
Neurosciences
Ryotaro Ide, Miho Ota, Yasushi Hada, Takumi Takahashi, Masashi Tamura, Kiyotaka Nemoto, Tetsuaki Arai
Summary: This study investigated the relationship between balance function and the volume of the hippocampus and its subfields. The findings suggest a positive correlation between balance function and the volume of the whole hippocampus and specific subfields in healthy elderly individuals. Therefore, balance function may be associated with hippocampal volume.
Article
Clinical Neurology
Daisuke Fujikane, Kazutaka Ohi, Kiyotaka Nemoto, Yuma Horibe, Yunako Ogawa, Runa Taguchi, Riko Toba, Toshiki Shioiri
Summary: This study investigates the genetic factors associated with anxiety disorders and their impact on cortical alterations. The findings suggest a shared genetic etiology between anxiety disorders and structural features of the anterior cingulate gyrus, which may contribute to the pathogenesis of anxiety disorders. The study also highlights the potential usefulness of polygenic risk scores in reducing pathological heterogeneity among anxiety disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Neurosciences
Hitoshi Iida, Tsuyoshi Okada, Kiyotaka Nemoto, Naomi Hasegawa, Shusuke Numata, Kazuyoshi Ogasawara, Kenichiro Miura, Junya Matsumoto, Hikaru Hori, Jun-ichi Iga, Kayo Ichihashi, Naoki Hashimoto, Hisashi Yamada, Kazutaka Ohi, Norio Yasui-Furukori, Kentaro Fukumoto, Takashi Tsuboi, Masahide Usami, Ryuji Furihata, Yoshikazu Takaesu, Akitoyo Hishimoto, Hiroyuki Muraoka, Eiichi Katsumoto, Tatsuya Nagasawa, Shinichiro Ochi, Hiroshi Komatsu, Saya Kikuchi, Masahiro Takeshima, Toshiaki Onitsuka, Shinichiro Tamai, Chika Kubota, Ken Inada, Koichiro Watanabe, Hiroaki Kawasaki, Ryota Hashimoto
Summary: The EGUIDE project was launched in 2016 to disseminate, educate, and validate psychiatric clinical practice guidelines. This study compared the effectiveness of web-based courses and face-to-face courses offered by the project. The results showed that web-based courses were rated as more satisfying than expected and there were no significant differences in satisfaction and clinical knowledge between the two formats. This suggests that web-based courses could be widely adopted alongside face-to-face courses after the COVID-19 pandemic.
NEUROPSYCHOPHARMACOLOGY REPORTS
(2023)
Article
Health Care Sciences & Services
Kenta Yoshii, Daiki Kimura, Akihiro Kosugi, Kaoru Shinkawa, Toshiro Takase, Masatomo Kobayashi, Yasunori Yamada, Miyuki Nemoto, Ryohei Watanabe, Miho Ota, Shinji Higashi, Kiyotaka Nemoto, Tetsuaki Arai, Masafumi Nishimura
Summary: This study found that prosodic and acoustic features from conversations with a humanoid robot can be used to detect mild cognitive impairment (MCI) at an early stage with the same level of accuracy as the Mini-Mental State Examination (MMSE). This is significant for reducing the workload of elderly care.
JMIR FORMATIVE RESEARCH
(2023)
Article
Neurosciences
Hirofumi Tomiyama, Keitaro Murayama, Kiyotaka Nemoto, Mayumi Tomita, Kenta Kato, Akira Matsuo, Aikana Ohno, Mingi Kang, Osamu Togao, Kousei Ishigami, Tomohiro Nakao
Summary: Previous studies have shown that specific fronto-striatal circuits are related to impaired motor response inhibition in patients with OCD and their relatives. However, no study has investigated the resting-state network associated with motor response inhibition in unaffected first-degree relatives. This study found group differences in the functional connectivity between the pre-SMA and inferior parietal lobule, and reduced connectivity was associated with longer stop-signal reaction time in relatives. Additionally, altered connectivity in the sensorimotor region was observed in relatives, similar to OCD patients.
Article
Neurosciences
Hirofumi Tomiyama, Keitaro Murayama, Kiyotaka Nemoto, Kenta Kato, Akira Matsuo, Aikana Ohno, Mingi Kang, Osamu Togao, Kousei Ishigami, Tomohiro Nakao
Summary: Gyrification patterns are indicative of early neurodevelopment and may have a strong heritable component. Although findings have been inconsistent, it has been consistently observed that patients with obsessive-compulsive disorder exhibit altered gyrification patterns in the orbitofrontal cortex. However, no studies have yet examined gyrification alterations in unaffected first-degree relatives of these patients.
Article
Neurosciences
Daiki Sasabayashi, Tsutomu Takahashi, Yoichiro Takayanagi, Kiyotaka Nemoto, Maya Ueno, Atsushi Furuichi, Yuko Higuchi, Yuko Mizukami, Haruko Kobayashi, Yusuke Yuasa, Kyo Noguchi, Michio Suzuki
Summary: This study investigated the disrupted functional connectivity of the default mode network in schizophrenia patients and individuals at-risk mental state (ARMS) using resting-state functional MRI. The results showed that schizophrenia patients had increased connectivity within the default mode network and with other brain regions, while ARMS individuals had increased connectivity only between the default mode network and occipital cortex. In schizophrenia, the functional connectivity of the lateral parietal cortex with the superior temporal gyrus was positively correlated with negative symptoms, while in ARMS, the functional connectivity of the lateral parietal cortex with the interparietal sulcus was negatively correlated with general cognitive impairment. These findings suggest that the increased connectivity between the default mode network and visual network seen in schizophrenia and ARMS subjects may reflect a general vulnerability to psychosis, and the connectivity changes related to the lateral parietal cortex may underpin the clinical characteristics of ARMS and schizophrenia subjects.
Article
Computer Science, Artificial Intelligence
Yasunori Yamada, Kaoru Shinkawa, Miyuki Nemoto, Kiyotaka Nemoto, Tetsuaki Arai
Summary: Speech analysis can be used as a screening tool for early detection of Alzheimer's disease (AD) and mild cognitive impairment (MCI). Automatic speech analysis, including speech recognition, can accurately classify AD, MCI, and cognitively normal (CN) groups with an accuracy of 78.6%.
COMPUTER SPEECH AND LANGUAGE
(2023)
Article
Psychiatry
Haruhiko Midorikawa, Hirokazu Tachikawa, Natsuho Kushibiki, Keiko Wataya, Sho Takahashi, Yuki Shiratori, Kiyotaka Nemoto, Shinichiro Sasahara, Shotaro Doki, Daisuke Hori, Ichiyo Matsuzaki, Testuaki Arai, Kunihiro Yamagata
Summary: This study aimed to investigate the relationship between fear of COVID-19, resilience, and psychological distress among healthcare workers treating COVID-19 patients. The findings revealed that occupation, fear of COVID-19, and resilience were important factors influencing psychological distress. Therefore, creating consultation services for healthcare workers to discuss their concerns and strengthening their resilience are crucial for providing mental healthcare during a pandemic.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Biochemistry & Molecular Biology
Junya Matsumoto, Masaki Fukunaga, Kenichiro Miura, Kiyotaka Nemoto, Naohiro Okada, Naoki Hashimoto, Kentaro Morita, Daisuke Koshiyama, Kazutaka Ohi, Tsutomu Takahashi, Michihiko Koeda, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Satsuki Ito, Ryuichi Yamazaki, Naomi Hasegawa, Hisashi Narita, Satoshi Yokoyama, Ryo Mishima, Jun Miyata, Yuko Kobayashi, Daiki Sasabayashi, Kenichiro Harada, Maeri Yamamoto, Yoji Hirano, Takashi Itahashi, Masahito Nakataki, Ryu-ichiro Hashimoto, Khin K. Tha, Shinsuke Koike, Toshio Matsubara, Go Okada, Reiji Yoshimura, Osamu Abe, Theo G. M. van Erp, Jessica A. Turner, Neda Jahanshad, Paul M. Thompson, Toshiaki Onitsuka, Yoshiyuki Watanabe, Koji Matsuo, Hidenori Yamasue, Yasumasa Okamoto, Michio Suzuki, Norio Ozaki, Kiyoto Kasai, Ryota Hashimoto
Summary: According to operational diagnostic criteria, psychiatric disorders such as schizophrenia, bipolar disorder, major depressive disorder, and autism spectrum disorder are classified based on symptoms. This study explored the similarities and differences in cortical structural neuroimaging features among these disorders. The findings revealed common patterns of cortical thickness and surface area alterations among schizophrenia, bipolar disorder, and major depressive disorder.
MOLECULAR PSYCHIATRY
(2023)
Article
Biochemistry & Molecular Biology
Naohiro Okada, Masaki Fukunaga, Kenichiro Miura, Kiyotaka Nemoto, Junya Matsumoto, Naoki Hashimoto, Masahiro Kiyota, Kentaro Morita, Daisuke Koshiyama, Kazutaka Ohi, Tsutomu Takahashi, Michihiko Koeda, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Naomi Hasegawa, Hisashi Narita, Satoshi Yokoyama, Ryo Mishima, Takahiko Kawashima, Yuko Kobayashi, Daiki Sasabayashi, Kenichiro Harada, Maeri Yamamoto, Yoji Hirano, Takashi Itahashi, Masahito Nakataki, Ryu-ichiro Hashimoto, Khin K. Tha, Shinsuke Koike, Toshio Matsubara, Go Okada, Theo G. M. van Erp, Neda Jahanshad, Reiji Yoshimura, Osamu Abe, Toshiaki Onitsuka, Yoshiyuki Watanabe, Koji Matsuo, Hidenori Yamasue, Yasumasa Okamoto, Michio Suzuki, Jessica A. Turner, Paul M. Thompson, Norio Ozaki, Kiyoto Kasai, Ryota Hashimoto
Summary: This article discusses the difficulties in differential diagnosis in practical psychiatric settings and the prospect of creating a novel diagnostic system using objective biomarkers. Neuroimaging studies have shown that subcortical brain structures are associated with various psycho-behavioral functions, but there are currently no neuroimaging data-driven clinical criteria that can overcome the limitations of the current diagnostic system in reflecting cognitive/social functioning. The authors conducted a large-scale study and found volumetric and lateralization alterations in several psychiatric disorders, which were associated with cognitive/social functioning.
MOLECULAR PSYCHIATRY
(2023)
Article
Geriatrics & Gerontology
Miho Ota, Kiyotaka Nemoto, Miyuki Nemoto, Yuriko Numata, Ayako Kitabatake, Yasunori Yamada, Kaoru Shinkawa, Masatomo Kobayashi, Tetsuaki Arai
Summary: This study uses magnetic resonance imaging to investigate the alterations in cerebral networks in the early stages of Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). The results suggest that changes in the degree of connectivity in specific brain regions may serve as potential biomarkers for the early detection of AD and DLB.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
(2023)
