Oral Administration of Fucoidan Can Exert Anti-Allergic Activity after Allergen Sensitization by Enhancement of Galectin-9 Secretion in Blood

A review about the development of fucoidan in antitumor activity: Progress and challenges

(2016) Lei Wu et al.   CARBOHYDRATE POLYMERS

F-fucoidan from Saccharina japonica is a novel inducer of galectin-9 and exhibits anti-allergic activity

(2016) Yuka Tanino et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

A novel in vitro co-culture model comprised of Caco-2/RBL-2H3 cells to evaluate anti-allergic effects of food factors through the intestine

(2016) Sae Yamashita et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antithrombotic activity of oral administered low molecular weight fucoidan from Laminaria Japonica

(2016) Xue Zhao et al.   THROMBOSIS RESEARCH

n-3 Polyunsaturated fatty acids inhibit Fc ε receptor I-mediated mast cell activation

(2015) Xiaofeng Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Galectin-9 Increases Tim-3+ Dendritic Cells and CD8+ T Cells and Enhances Antitumor Immunity via Galectin-9-Tim-3 Interactions

(2014) K. Nagahara et al.   JOURNAL OF IMMUNOLOGY

The beneficial properties of marine polysaccharides in alleviation of allergic responses

(2014) Thanh-Sang Vo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Galectin-9 Enhances Cytokine Secretion, but Suppresses Survival and Degranulation, in Human Mast Cell Line

(2014) Reiji Kojima et al.   PLoS One

Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown alga Laminaria japonica in human subjects

(2013) Rendong Ren et al.   BRITISH JOURNAL OF NUTRITION

Brown seaweed fucoidan: Biological activity and apoptosis, growth signaling mechanism in cancer

(2013) Kalimuthu Senthilkumar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Galectin-9 induced by dietary synbiotics is involved in suppression of allergic symptoms in mice and humans

(2012) S. Kivit et al.   ALLERGY

IgE and mast cells in allergic disease

(2012) Stephen J Galli et al.   NATURE MEDICINE

Cell Surface Galectin-9 Expressing Th Cells Regulate Th17 and Foxp3+ Treg Development by Galectin-9 Secretion

(2012) Souichi Oomizu et al.   PLoS One

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine

(2011) X. Chen et al.   ALLERGY

Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo

(2011) Marcel Tutor Ale et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Galectin-9 Protein Expression in Endothelial Cells Is Positively Regulated by Histone Deacetylase 3

(2011) Saydul Alam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunomodulatory dietary polysaccharides: a systematic review of the literature

(2010) Jane E Ramberg et al.   Nutrition Journal

Peritoneal injection of fucoidan suppresses the increase of plasma IgE induced by OVA-sensitization

(2009) Yuhki Yanase et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Morin inhibits Fyn kinase in mast cells and IgE-mediated type I hypersensitivity response in vivo

(2009) Jie Wan Kim et al.   BIOCHEMICAL PHARMACOLOGY

Galectin-9 Is a High Affinity IgE-binding Lectin with Anti-allergic Effect by Blocking IgE-Antigen Complex Formation

(2009) Toshiro Niki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Fucoidan: Structure and Bioactivity

(2008) Bo Li et al.   MOLECULES

The development of allergic inflammation

(2008) Stephen J. Galli et al.   NATURE