Bioengineered Platforms for Chronic Wound Infection Studies: How Can We Make Them More Human-Relevant?

Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion

(2019) Ajitha Thanabalasuriar et al.   Cell Host & Microbe

Neutrophils Facing Biofilms: The Battle of the Barriers

(2019) Venizelos Papayannopoulos   Cell Host & Microbe

Fabrication of Microfluidic Chip for Investigation of Wound Healing Processes

(2018) Hani Go et al.   BioChip Journal

Monitoring of bacteria biofilms forming process by in-situ impedimetric biosensor chip

(2018) Lulu Liu et al.   BIOSENSORS & BIOELECTRONICS

Development and Characterisation of a Human Chronic Skin Wound Cell Line—Towards an Alternative for Animal Experimentation

(2018) Matthew Caley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Validation of biofilm formation on human skin wound models and demonstration of clinically translatable bacteria-specific volatile signatures

(2018) Mohammed Ashrafi et al.   Scientific Reports

Development of a High-Throughput ex-Vivo Burn Wound Model Using Porcine Skin, and Its Application to Evaluate New Approaches to Control Wound Infection

(2018) Diana R. Alves et al.   Frontiers in Cellular and Infection Microbiology

Interaction between Staphylococcus aureus and Pseudomonas aeruginosa is beneficial for colonisation and pathogenicity in a mixed biofilm

(2018) Patrícia M Alves et al.   Pathogens and Disease

The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Pro-wound Healing Phenotypes

(2018) Paulina Krzyszczyk et al.   Frontiers in Physiology

The Interplay Between Keratinocytes and Immune Cells in the Pathogenesis of Psoriasis

(2018) Cristina Albanesi et al.   Frontiers in Immunology

Mechanical Forces in Cutaneous Wound Healing: Emerging Therapies to Minimize Scar Formation

(2018) Leandra A. Barnes et al.   Advances in Wound Care

Fungi in the Wound Microbiome

(2018) Lindsay Kalan et al.   Advances in Wound Care

NOVEL ASSAY TO CHARACTERIZE NEUTROPHIL RESPONSES TO ORAL BIOFILMS

(2018) Morvarid Oveisi et al.   INFECTION AND IMMUNITY

Development, standardization and testing of a bacterial wound infection model based on ex vivo human skin

(2017) Christoph Schaudinn et al.   PLoS One

Mechanosensing of shear byPseudomonas aeruginosaleads to increased levels of the cyclic-di-GMP signal initiating biofilm development

(2017) Christopher A. Rodesney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Porcine Models of Biofilm Infections with Focus on Pathomorphology

(2017) Louise K. Jensen et al.   Frontiers in Microbiology

The health economic burden that acute and chronic wounds impose on an average clinical commissioning group/health board in the UK

(2017) J. F. Guest et al.   Journal of Wound Care

The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

(2017) M. Malone et al.   Journal of Wound Care

nBio Chip, a Lab-on-a-Chip Platform of Mono- and Polymicrobial Biofilms for High-Throughput Downstream Applications

(2017) Anand Srinivasan et al.   mSphere

Bacterial biofilm under flow: First a physical struggle to stay, then a matter of breathing

(2017) Philippe Thomen et al.   PLoS One

Development of a Novel Collagen Wound Model To Simulate the Activity and Distribution of Antimicrobials in Soft Tissue during Diabetic Foot Infection

(2016) Bianca L. Price et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Development and characterisation of a novel three-dimensional inter-kingdom wound biofilm model

(2016) Eleanor M. Townsend et al.   BIOFOULING

Growth of MRSA andPseudomonas aeruginosain a fine-celled foam model containing sessile commensal skin bacteria

(2016) Angela Oates et al.   BIOFOULING

Transition from inflammation to proliferation: a critical step during wound healing

(2016) Ning Xu Landén et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Diffusion Barriers, Mechanical Forces, and the Biophysics of Phagocytosis

(2016) Philip P. Ostrowski et al.   DEVELOPMENTAL CELL

Angiogenesis and wound repair: when enough is enough

(2016) Luisa A. DiPietro   JOURNAL OF LEUKOCYTE BIOLOGY

Antibiofilm efficacy of honey and bee-derived defensin-1 on multispecies wound biofilm

(2016) Martin Sojka et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Microsensor and transcriptomic signatures of oxygen depletion in biofilms associated with chronic wounds

(2016) Garth A. James et al.   WOUND REPAIR AND REGENERATION

Redefining the Chronic-Wound Microbiome: Fungal Communities Are Prevalent, Dynamic, and Associated with Delayed Healing

(2016) Lindsay Kalan et al.   mBio

The Role of Matrix Metalloproteinases in Diabetic Wound Healing in relation to Photobiomodulation

(2016) Sandra Matabi Ayuk et al.   Journal of Diabetes Research

Extracellular Matrix and Dermal Fibroblast Function in the Healing Wound

(2016) Lauren E. Tracy et al.   Advances in Wound Care

Tobramycin and bicarbonate synergise to kill planktonic Pseudomonas aeruginosa, but antagonise to promote biofilm survival

(2016) Karishma S Kaushik et al.   npj Biofilms and Microbiomes

Prototype Development of the Intelligent Hydrogel Wound Dressing and Its Efficacy in the Detection of Model Pathogenic Wound Biofilms

(2015) N. T. Thet et al.   ACS Applied Materials & Interfaces

On-chip assay of the effect of topographical microenvironment on cell growth and cell-cell interactions during wound healing

(2015) Yanfei An et al.   Biomicrofluidics

Soluble factors from biofilms of wound pathogens modulate human bone marrow-derived stromal cell differentiation, migration, angiogenesis, and cytokine secretion

(2015) Catherine L Ward et al.   BMC MICROBIOLOGY

Porcine Models of Cutaneous Wound Healing

(2015) M. Seaton et al.   ILAR JOURNAL

The spatial profiles and metabolic capabilities of microbial populations impact the growth of antibiotic-resistant mutants

(2015) K. S. Kaushik et al.   Journal of the Royal Society Interface

Infection and immunity on a chip: a compartmentalised microfluidic platform to monitor immune cell behaviour in real time

(2015) N. Gopalakrishnan et al.   LAB ON A CHIP

Chronic Wound Biofilms: Pathogenesis and Potential Therapies

(2015) Allie Clinton et al.   Labmedicine

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

(2015) Ana Perestrelo et al.   SENSORS

Reactive oxygen species (ROS) and wound healing: the functional role of ROS and emerging ROS-modulating technologies for augmentation of the healing process

(2015) Christopher Dunnill et al.   International Wound Journal

Health economic burden that wounds impose on the National Health Service in the UK

(2015) Julian F Guest et al.   BMJ Open

Chronic Wound Biofilms: Pathogenesis and Potential Therapies

(2015) Allie Clinton et al.   LABORATORY MEDICINE

Chronic Wound Biofilm Model

(2015) Kasturi Ganesh et al.   Advances in Wound Care

Secreted biofilm factors adversely affect cellular wound healing responses in vitro

(2015) Robert Jeffery Marano et al.   Scientific Reports

Biofilms: Five-Star Accommodations for the Aerobically Challenged

(2014) Robert A. Cramer   CURRENT BIOLOGY

Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexity

(2014) Robert Nunan et al.   Disease Models & Mechanisms

Synergistic Interactions of Pseudomonas aeruginosa and Staphylococcus aureus in anIn VitroWound Model

(2014) Stephanie DeLeon et al.   INFECTION AND IMMUNITY

Early effects of Staphylococcus aureus biofilm secreted products on inflammatory responses of human epithelial keratinocytes

(2014) Amy Tankersley et al.   Journal of Inflammation-London

A Novel Model of Chronic Wounds: Importance of Redox Imbalance and Biofilm-Forming Bacteria for Establishment of Chronicity

(2014) Sandeep Dhall et al.   PLoS One

Wound healing: an update

(2014) Elizabeth R Zielins et al.   Regenerative Medicine

The effects of pH on wound healing, biofilms, and antimicrobial efficacy

(2014) Steven L. Percival et al.   WOUND REPAIR AND REGENERATION

Immunology and Skin in Health and Disease

(2014) J. M. Richmond et al.   Cold Spring Harbor Perspectives in Medicine

Effects of biofilm treatments on the multi-species Lubbock chronic wound biofilm model

(2014) S.E. Dowd et al.   Journal of Wound Care

Propagation of anaerobic bacteria within an aerobic multi-species chronic wound biofilm model

(2014) Y. Sun et al.   Journal of Wound Care

Dynamic interactions of neutrophils and biofilms

(2014) Josefine Hirschfeld   Journal of Oral Microbiology

Inflammatory and Antimicrobial Responses to Methicillin-Resistant Staphylococcus aureus in an In Vitro Wound Infection Model

(2013) Elisabeth M. Haisma et al.   PLoS One

Development of a novel ex vivo porcine skin explant model for the assessment of mature bacterial biofilms

(2013) Qingping Yang et al.   WOUND REPAIR AND REGENERATION

Neutrophils and Wound Repair: Positive Actions and Negative Reactions

(2013) Traci A. Wilgus et al.   Advances in Wound Care

Biofilms and Inflammation in Chronic Wounds

(2013) Ge Zhao et al.   Advances in Wound Care

The Wound Microbiome: Modern Approaches to Examining the Role of Microorganisms in Impaired Chronic Wound Healing

(2013) Ana M. Misic et al.   Advances in Wound Care

Biophysical Technologies for Management of Wound Bioburden

(2013) Holly Korzendorfer et al.   Advances in Wound Care

Innate and Adaptive Immune Responses in Wound Epithelialization

(2013) Natasa Strbo et al.   Advances in Wound Care

Hypoxia Increases Antibiotic Resistance in Pseudomonas aeruginosa through Altering the Composition of Multidrug Efflux Pumps

(2012) Bettina Schaible et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Soft tissue mechanotransduction in wound healing and fibrosis

(2012) Victor W. Wong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Differential effects of planktonic and biofilm MRSA on human fibroblasts

(2012) Kelly R. Kirker et al.   WOUND REPAIR AND REGENERATION

Role of different negative pressure values in the process of infected wounds treated by vacuum-assisted closure: an experimental study

(2012) Min Zhou et al.   International Wound Journal

Oxygen: Implications for Wound Healing

(2012) Diego M. Castilla et al.   Advances in Wound Care

Clinically Addressing Biofilm in Chronic Wounds

(2012) Christopher Attinger et al.   Advances in Wound Care

Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, mapk phosphorylation, and cytokine production in human keratinocytes

(2011) Patrick R Secor et al.   BMC MICROBIOLOGY

A Review of the Role of Mechanical Forces in Cutaneous Wound Healing

(2011) Riaz Agha et al.   JOURNAL OF SURGICAL RESEARCH

Role of shear stress and stretch in vascular mechanobiology

(2011) D. Lu et al.   Journal of the Royal Society Interface

An In Vivo Polymicrobial Biofilm Wound Infection Model to Study Interspecies Interactions

(2011) Trevor Dalton et al.   PLoS One

Chronic wound fluid-thinking outside the box

(2011) Alan David Widgerow   WOUND REPAIR AND REGENERATION

Anin vitromodel of bacterial infections in wounds and other soft tissues

(2010) MARIA WERTHÉN et al.   APMIS

Factors Affecting Wound Healing

(2010) S. Guo et al.   JOURNAL OF DENTAL RESEARCH

Neutrophil kinetics in health and disease

(2010) Charlotte Summers et al.   TRENDS IN IMMUNOLOGY

In vitro multispecies Lubbock chronic wound biofilm model

(2010) Yan Sun et al.   WOUND REPAIR AND REGENERATION

A novel human skin chamber model to study wound infection ex vivo

(2009) Lars Steinstraesser et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

The Role of Doxycycline as a Matrix Metalloproteinase Inhibitor for the Treatment of Chronic Wounds

(2009) J. Stechmiller et al.   Biological Research for Nursing

Use of Tissue-Engineered Skin to Study In Vitro Biofilm Development

(2009) Carlos A. Charles et al.   DERMATOLOGIC SURGERY

Nonrandom Distribution of Pseudomonas aeruginosa and Staphylococcus aureus in Chronic Wounds

(2009) M. Fazli et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Wound healing essentials: Let there be oxygen

(2009) Chandan K. Sen   WOUND REPAIR AND REGENERATION

Loss of viability and induction of apoptosis in human keratinocytes exposed toStaphylococcus aureusbiofilms in vitro

(2009) Kelly R. Kirker et al.   WOUND REPAIR AND REGENERATION

Wound Healing Assays in Well Plate–Coupled Microfluidic Devices with Controlled Parallel Flow

(2009) Carolyn G. Conant et al.   Journal of the Association for Laboratory Automation.

The phagocytes: neutrophils and monocytes

(2008) D. C. Dale et al.   BLOOD

Differential innate immune responses of a living skin equivalent model colonized by Staphylococcus epidermidis or Staphylococcus aureus

(2008) Diana B. Holland et al.   FEMS MICROBIOLOGY LETTERS

Microbial colonization of anin vitromodel of a tissue engineered human skin equivalent – a novel approach

(2008) Diana B. Holland et al.   FEMS MICROBIOLOGY LETTERS

Distribution, Organization, and Ecology of Bacteria in Chronic Wounds

(2008) K. Kirketerp-Moller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing

(2008) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION

Biofilms in chronic wounds

(2008) Garth A. James et al.   WOUND REPAIR AND REGENERATION

The hypothesis of ‘biophysical matrix contraction’: wound contraction revisited

(2008) Ramin Mostofizadeh Farahani et al.   International Wound Journal

Fragments of extracellular matrix as mediators of inflammation

(2007) T ADAIRKIRK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY