Adherens Junctions: Guardians of Cortical Development

Deconstructing cortical folding: genetic, cellular and mechanical determinants

(2019) Cristina Llinares-Benadero et al.   NATURE REVIEWS NEUROSCIENCE

Role of adherens junctions and apical-basal polarity of neural stem/progenitor cells in the pathogenesis of neurodevelopmental disorders: a novel perspective on congenital Zika syndrome

(2019) Felipe A. Bustamante et al.   Translational Research

Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members

(2019) Gonzalo Ortiz-Álvarez et al.   NEURON

Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor

(2019) Stephanie A. Redmond et al.   Cell Reports

Malformations of Human Neocortex in Development – Their Progenitor Cell Basis and Experimental Model Systems

(2019) Anneline Pinson et al.   Frontiers in Cellular Neuroscience

Temporal plasticity of apical progenitors in the developing mouse neocortex

(2019) Polina Oberst et al.   NATURE

Switching states: dynamic remodelling of polarity complexes as a toolkit for cell polarization

(2019) Florent Peglion et al.   CURRENT OPINION IN CELL BIOLOGY

Biallelic loss of human CTNNA2, encoding αN-catenin, leads to ARP2/3 complex overactivity and disordered cortical neuronal migration

(2018) Ashleigh E. Schaffer et al.   NATURE GENETICS

Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7

(2018) Stefania Tavano et al.   NEURON

Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex

(2018) Ilaria Vitali et al.   CELL

Distinct Interaction Sites of Rac GTPase with WAVE Regulatory Complex Have Non-redundant Functions in Vivo

(2018) Matthias Schaks et al.   CURRENT BIOLOGY

A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress

(2018) Bipul R. Acharya et al.   DEVELOPMENTAL CELL

Loss of Lgl1 Disrupts the Radial Glial Fiber-guided Cortical Neuronal Migration and Causes Subcortical Band Heterotopia in Mice

(2018) Tingting Zhang et al.   NEUROSCIENCE

Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia

(2017) Jennifer Rakotomamonjy et al.   Neural Development

Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells

(2017) Robert Beattie et al.   NEURON

Functional Actin Networks under Construction: The Cooperative Action of Actin Nucleation and Elongation Factors

(2017) Orit Siton-Mendelson et al.   TRENDS IN BIOCHEMICAL SCIENCES

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

(2017) Christian Siebold et al.   TRENDS IN CELL BIOLOGY

The Diverse Family of Arp2/3 Complexes

(2017) Javier Pizarro-Cerdá et al.   TRENDS IN CELL BIOLOGY

Cell Polarity in Cerebral Cortex Development—Cellular Architecture Shaped by Biochemical Networks

(2017) Andi H. Hansen et al.   Frontiers in Cellular Neuroscience

Signaling by Small GTPases at Cell–Cell junctions: Protein Interactions Building Control and Networks

(2017) Vania Braga   Cold Spring Harbor Perspectives in Biology

Mechanosensing and Mechanotransduction at Cell–Cell Junctions

(2017) Alpha S. Yap et al.   Cold Spring Harbor Perspectives in Biology

Neogenin Recruitment of the WAVE Regulatory Complex to Ependymal and Radial Progenitor Adherens Junctions Prevents Hydrocephalus

(2017) Conor J. O’Leary et al.   Cell Reports

The Genetic Basis of Hydrocephalus

(2016) Maria Kousi et al.   Annual Review of Neuroscience

Crucial roles of the Arp2/3 complex during mammalian corticogenesis

(2016) Pei-Shan Wang et al.   DEVELOPMENT

Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation

(2016) Manuel Carminati et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels

(2016) Maria Ángeles Martínez-Martínez et al.   Nature Communications

Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus

(2016) Raehee Park et al.   Nature Communications

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension

(2016) Natalie K. Lee et al.   Nature Communications

Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation

(2016) Manuel Carminati et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Generating Neuronal Diversity in the Mammalian Cerebral Cortex

(2015) Simona Lodato et al.   Annual Review of Cell and Developmental Biology

Cortical Folding: When, Where, How, and Why?

(2015) Georg F. Striedter et al.   Annual Review of Neuroscience

Cell Junction Pathology of Neural Stem Cells Is Associated With Ventricular Zone Disruption, Hydrocephalus, and Abnormal Neurogenesis

(2015) María Montserrat Guerra et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

WAVE binds Ena/VASP for enhanced Arp2/3 complex–based actin assembly

(2015) Svitlana Havrylenko et al.   MOLECULAR BIOLOGY OF THE CELL

The Netrin/RGM Receptor, Neogenin, Controls Adult Neurogenesis by Promoting Neuroblast Migration and Cell Cycle Exit

(2015) Conor J. O'Leary et al.   STEM CELLS

Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia

(2015) Gewei Lian et al.   Frontiers in Cellular Neuroscience

The role of adherens junctions in the developing neocortex

(2015) Adam M Stocker et al.   Cell Adhesion & Migration

The Cell Biology of Neurogenesis: Toward an Understanding of the Development and Evolution of the Neocortex

(2014) Elena Taverna et al.   Annual Review of Cell and Developmental Biology

The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton

(2014) Baoyu Chen et al.   CELL

Modeling a Genetic Risk for Schizophrenia in iPSCs and Mice Reveals Neural Stem Cell Deficits Associated with Adherens Junctions and Polarity

(2014) Ki-Jun Yoon et al.   Cell Stem Cell

Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates

(2014) J. Hatakeyama et al.   DEVELOPMENT

Neurogenesis during development of the vertebrate central nervous system

(2014) J. T. Paridaen et al.   EMBO REPORTS

Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology

(2014) Neeraj Jain et al.   EXPERIMENTAL NEUROLOGY

Cortactin Scaffolds Arp2/3 and WAVE2 at the Epithelial Zonula Adherens

(2014) Siew Ping Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proliferative Defects and Formation of a Double Cortex in Mice Lacking Mltt4 and Cdh2 in the Dorsal Telencephalon

(2014) C. Gil-Sanz et al.   JOURNAL OF NEUROSCIENCE

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

(2014) Selwin K. Wu et al.   NATURE CELL BIOLOGY

Apical Abscission Alters Cell Polarity and Dismantles the Primary Cilium During Neurogenesis

(2014) R. M. Das et al.   SCIENCE

The minimal cadherin-catenin complex binds to actin filaments under force

(2014) C. D. Buckley et al.   SCIENCE

The role of α-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration

(2014) Marie-Theres Schmid et al.   Frontiers in Cellular Neuroscience

Asymmetric Inheritance of Centrosome-Associated Primary Cilium Membrane Directs Ciliogenesis after Cell Division

(2013) Judith T.M.L. Paridaen et al.   CELL

Disruption of CDH2/N-Cadherin–Based Adherens Junctions Leads to Apoptosis of Ependymal Cells and Denudation of Brain Ventricular Walls

(2013) Cristian Oliver et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition–like mechanism

(2013) Yasuhiro Itoh et al.   NATURE NEUROSCIENCE

Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate

(2013) Marion Betizeau et al.   NEURON

GPR56 Functions Together with α3β1 Integrin in Regulating Cerebral Cortical Development

(2013) Sung-Jin Jeong et al.   PLoS One

Genetic Deletion of Afadin Causes Hydrocephalus by Destruction of Adherens Junctions in Radial Glial and Ependymal Cells in the Midbrain

(2013) Hideaki Yamamoto et al.   PLoS One

The secondary loss of gyrencephaly as an example of evolutionary phenotypical reversal

(2013) Iva Kelava et al.   Frontiers in Neuroanatomy

A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus

(2012) Esteban M Rodríguez et al.   BIOLOGICAL RESEARCH

Cadherin junctions and their cytoskeleton(s)

(2012) William M Brieher et al.   CURRENT OPINION IN CELL BIOLOGY

Rab14 and Its Exchange Factor FAM116 Link Endocytic Recycling and Adherens Junction Stability in Migrating Cells

(2012) Andrea Linford et al.   DEVELOPMENTAL CELL

A WAVE2–Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

(2012) Suzie Verma et al.   MOLECULAR BIOLOGY OF THE CELL

A Radial Glia-Specific Role of RhoA in Double Cortex Formation

(2012) Silvia Cappello et al.   NEURON

E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch

(2012) N. Borghi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells

(2012) J.-L. Maitre et al.   SCIENCE

Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination

(2011) M. Wilsch-Brauninger et al.   DEVELOPMENT

A glial origin for periventricular nodular heterotopia caused by impaired expression of Filamin-A

(2011) Aurelie Carabalona et al.   HUMAN MOLECULAR GENETICS

Oblique Radial Glial Divisions in the Developing Mouse Neocortex Induce Self-Renewing Progenitors outside the Germinal Zone That Resemble Primate Outer Subventricular Zone Progenitors

(2011) A. Shitamukai et al.   JOURNAL OF NEUROSCIENCE

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway

(2011) Eva M. Kovacs et al.   NATURE CELL BIOLOGY

Dual Roles of Notch in Regulation of Apically Restricted Mitosis and Apicobasal Polarity of Neuroepithelial Cells

(2011) Shinya Ohata et al.   NEURON

The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells

(2011) Maria K. Lehtinen et al.   NEURON

Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

(2011) Maria Pia Postiglione et al.   NEURON

Deficiency of mDia, an Actin Nucleator, Disrupts Integrity of Neuroepithelium and Causes Periventricular Dysplasia

(2011) Dean Thumkeo et al.   PLoS One

Multicomponent Analysis of Junctional Movements Regulated by Myosin II Isoforms at the Epithelial Zonula Adherens

(2011) Michael Smutny et al.   PLoS One

Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation

(2011) K.-i. Katayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells

(2010) Eurico Morais-de-Sá et al.   CELL

A Role for Intermediate Radial Glia in the Tangential Expansion of the Mammalian Cerebral Cortex

(2010) Isabel Reillo et al.   CEREBRAL CORTEX

Crumbs/DaPKC-Dependent Apical Exclusion of Bazooka Promotes Photoreceptor Polarity Remodeling

(2010) Rhian F. Walther et al.   CURRENT BIOLOGY

Structure and control of the actin regulatory WAVE complex

(2010) Zhucheng Chen et al.   NATURE

Neural Progenitor Nuclei IN Motion

(2010) Elena Taverna et al.   NEURON

The Apical Complex Couples Cell Fate and Cell Survival to Cerebral Cortical Development

(2010) Seonhee Kim et al.   NEURON

Development, specification, and diversity of callosal projection neurons

(2010) Ryann M. Fame et al.   TRENDS IN NEUROSCIENCES

Ependymal cells: biology and pathology

(2009) Marc R. Del Bigio   ACTA NEUROPATHOLOGICA

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex

(2009) Tom Kowalczyk et al.   CEREBRAL CORTEX

Adherens junction domains are split by asymmetric division of embryonic neural stem cells

(2009) Véronique Marthiens et al.   EMBO REPORTS

Disruption of the Neurogenic Niche in the Subventricular Zone of Postnatal Hydrocephalic hyh Mice

(2009) Antonio Jesús Jiménez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

(2009) Xiaoqun Wang et al.   NATURE

Mammalian Par3 Regulates Progenitor Cell Asymmetric Division via Notch Signaling in the Developing Neocortex

(2009) Ronald S. Bultje et al.   NEURON

β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche

(2009) Karine Loulier et al.   PLOS BIOLOGY

Regulation of Neurogenesis by Interkinetic Nuclear Migration through an Apical-Basal Notch Gradient

(2008) Filippo Del Bene et al.   CELL

The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development

(2008) Lilla M Farkas et al.   CURRENT OPINION IN CELL BIOLOGY

Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia

(2008) Russell J. Ferland et al.   HUMAN MOLECULAR GENETICS

Emerging roles for neogenin and its ligands in CNS development

(2008) Melissa De Vries et al.   JOURNAL OF NEUROCHEMISTRY

Neogenin and RGMa Control Neural Tube Closure and Neuroepithelial Morphology by Regulating Cell Polarity

(2008) N. Kee et al.   JOURNAL OF NEUROSCIENCE